A5023763499- Endometriosis Research and Treatment
- Reproductive Biology and Fertility
- Ovarian function and disorders
- Spinal Dysraphism and Malformations
- Selenium in Biological Systems
- Gynecological conditions and treatments
- Endometrial and Cervical Cancer Treatments
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Genital Health and Disease
- TGF-β signaling in diseases
- Grief, Bereavement, and Mental Health
- Vitamin D Research Studies
- Pelvic floor disorders treatments
- Biomarkers in Disease Mechanisms
- Male Breast Health Studies
- Data-Driven Disease Surveillance
- Urinary and Genital Oncology Studies
- Assisted Reproductive Technology and Twin Pregnancy
- Adipokines, Inflammation, and Metabolic Diseases
- Anorectal Disease Treatments and Outcomes
- Hypothalamic control of reproductive hormones
- Teratomas and Epidermoid Cysts
- Sexual Differentiation and Disorders
- Heavy Metal Exposure and Toxicity
- Cancer Cells and Metastasis
Medical University of Silesia
2013-2024
Medical University of Lublin
2021
Wroclaw Medical University
2020-2021
The Maria Sklodowska-Curie National Research Institute of Oncology
2020
Wojewódzki Szpital Specjalistyczny nr 4 w Bytomiu
2013
Anti-Müllerian hormone (AMH) is considered to be one of the most significant indicators women's fertility. Many studies have shown that vitamin D may modify human reproductive functions; however, results are conflicting. The composition follicular fluid (FF) creates biochemical environment oocyte and affects its quality, which later determines embryo quality. In this study, we aimed revise with advanced statistical techniques relationship between AMH in FF.The study was designed as a...
A population-based organised cervical cancer screening programme (OCCSP) was introduced in Poland 2006. In this study we have aimed to analyse whether selected parameters related invasive (ICC) of patients diagnosed two distant gynaecological oncology centres changed after the first round run between 2006–2008. We a retrospective cross-sectional analysis 189 women with ICC 2002–2005 (directly before introduction programme) and 165 2009–2012 (just compared their age at diagnosis, histology,...
Background . Oxidative stress appears to be involved in oocyte growth and maturation that when impaired results poor embryo quality lower potential implant. The biochemical microenvironment of the (follicular fluid (FF)) consists hormones other various substances regulating balance between oxidants antioxidants. Aim aim this study was examine possible impact selected biomarkers (“every day,” hormonal biomarkers, enzymatic nonenzymatic antioxidants, also oxidative markers) serum FF, on...
Myelomeningocele (MMC) constitutes the most common congenital defect of central nervous system, with no satisfactory alternative to postnatal treatment. Prenatal repair MMC is aimed at protecting from a Chiari type II malformation. The main goal fetal improve development and quality life in children Management Study (MOMS), which was published 2011, confirmed effectiveness prenatal surgery. In this paper, we compared MOMS results our own clinical experience. Owing high significant...
Environmental factors may negatively contribute to a progressive worsening of semen quality, and differences in quality result from different environmental exposures (regional differences) or lifestyle differences. Heavy metals are with confirmed negative influence on male fertility. Among them, lead cadmium commonly found human surroundings. Thus, we analyzed parameters (according the World Health Organization 2010 recommendations) concentrations 188 men two regions Poland, typical...
Vulvar cancer accounts for about 3-5% of all female genital carcinomas.TGF-` protein is a member superfamily cytokines that regulate cell functions.A correlation between this and many neoplastic processes was reported. Objectives: In our study we analyzed TGF-` expression in vulvar tumor among patients with diagnosed squamous carcinoma (with without inguinal nodes metastases).Material methods: Paraffin embedded blocks obtained from tissues (from 31 FIGO II-IV) were prepared.Next, the...
Fetal and maternal risks associated with open fetal surgery (OFS) in the management of meningomyelocele (MMC) are considerable necessitate improvement. A modified technique hysterotomy (without a uterine stapler) magnesium-free tocolysis (with Sevoflurane as only muscle relaxant) was implemented our new classical (MgFTCH) protocol. The aim study to assess introduction MgFTCH protocol reducing complications. prospective cohort (SC) included 64 OFS performed at Surgery Centre Bytom (FSCB)...
1. Nowak I, Bylińska A, Wilczyńska K, et al. The methylenetetrahydrofolate reductase c.c.677 C>T and c.c.1298 A>C polymorphisms in reproductive failures: Experience from an RSA RIF study on a Polish population. PLoS One. 2017 Oct 26;12(10):e0186022. doi:10.1371/journal.pone.0186022. CrossRef Google Scholar
Identifying patients at high risk of in-hospital mortality within the early days admission is crucial for guiding medical decisions and allocating resources effectively. This study aimed to explore whether changes in routinely conducted tests were associated with sudden death among (all causes) Regional Hospital Racibórz, Poland. The first laboratory ten biomarkers from 7,827 unique examined, January 1 December 31, 2023. Associations between factors all-cause outcomes estimated using Cox...
The purpose of our study was to determine the influence lead and cadmium in concentrations commonly found environment on redox system follicular fluid (FF) results assisted reproduction. A prospective 113 patients with unexplained infertility who qualified for intracytoplasmic sperm injection (ICSI). Patients moderate or severe endometriosis poor ovarian reserve were excluded from study. Biochemical analyses heavy metal assays serum (blood) followed by statistical dependencies between...
Introduction: Changes in sex hormone secretions during the menstrual cycle may affect fertility. It has been shown that a prematurely raised progesterone (P4) level after therapeutic injection of human chorionic gonadotropin caused changes endometrial gene expression and lowered pregnancy rate. The aim present study was to investigate complete patterns P4 together with its derivatives testosterone (T) oestradiol (E2) subfertile women their natural cycles. Material methods: Daily serum levels...
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Olejek A, Kozak-Darmas I, Olszak-Wąsik K. Evaluation of concentration thyroid antibodies, antinuclear antibody titers and presence Borrelia burgdorferi antibodies in patients with vulvar lichen sclerosus treated photodynamic therapy. Menopause Review/Przegląd Menopauzalny. 2012;11(4):275-280. doi:10.5114/pm.2012.30229. APA Olejek, A., Kozak-Darmas, I., & Olszak-Wąsik, (2012). Menopauzalny, 11(4), 275-280....
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Olejek A, Olszak-Wąsik K, Stęplewska et al. Efficacy of PDT in vulvar LS treatment based on immunohistochemical analysis CD3, CD4, CD8, CD57, Granzyme B and Fascin expression. Menopause Review/Przegląd Menopauzalny. 2013;12(2):155-158. doi:10.5114/pm.2013.35075. APA Olejek, A., Olszak-Wąsik, K., Stęplewska, Horák, S., Zamłyński, J., & Kozak-Darmas, I. (2013). Menopauzalny, 12(2), 155-158....
Rak pochwy jest rzadkim nowotworem i w 65%-90% przypadków to przerzut innego nowotworu.Rak diagnozowany przede wszystkim wśród pacjentek 60-70 letnich, chociaż opisywany także grupie kobiet młodszych.Najczęstszym stwierdzanym typem histopatologicznym rak płaskonabłonkowy.Uważa się, że czynniki rozwoju raka są zbliżone do czynników ryzyka
Abstract Background In this paper we focus on 46, XY pure gonadal dysgenesis-Swyer syndrome. MethodsWe present the case of a 33-year old patient and medical procedures enabling to achieve pregnancy in couple struggling with infertility.We analyzed patient’s history, scheduled further diagnostic therapeutic that included genetic tests consultations, MRI (magnetic resonance imaging), laparoscopy, oncological risk assesment possibilities pregnancy.Results Patients history revealed her last...
The aim of the present study was to create spatial and spatio-temporal patterns cutaneous malignant melanoma (MM) incidence in Upper Silesia, Poland, using largest MM database (<4K cases) Central Europe, focusing on agricultural sector. data comprised all registered cancer cases (C43, according International Classification Diseases after 10th Revision) between years 2004-2013 by Regional Cancer Registries (RCRs) Opole Gliwice. standardized ratios (SIRs), growth rates (GRs), disease cluster...