A5030964229- Genital Health and Disease
- Neuroendocrine Tumor Research Advances
- Helicobacter pylori-related gastroenterology studies
- Cancer-related Molecular Pathways
- Oral and Maxillofacial Pathology
- Thyroid Cancer Diagnosis and Treatment
- Medical Imaging and Pathology Studies
- Urological Disorders and Treatments
- Cancer, Hypoxia, and Metabolism
- Head and Neck Cancer Studies
- Salivary Gland Tumors Diagnosis and Treatment
- Glycosylation and Glycoproteins Research
- Gastric Cancer Management and Outcomes
- Lymphoma Diagnosis and Treatment
- Lung Cancer Research Studies
- Cancer Cells and Metastasis
- Neuroblastoma Research and Treatments
- Genetic factors in colorectal cancer
- Nasolacrimal Duct Obstruction Treatments
- Ocular Oncology and Treatments
- Anesthesia and Neurotoxicity Research
- Cardiac Structural Anomalies and Repair
- Vascular Tumors and Angiosarcomas
- Caveolin-1 and cellular processes
- Esophageal Cancer Research and Treatment
University of Opole
2018-2023
Medical University of Silesia
2010-2022
Weatherford College
2022
Górnośląskie Centrum Medyczne
2012-2017
Wojewódzki Szpital Specjalistyczny nr 4 w Bytomiu
2009
Silesian Center for Heart Disease
1999-2004
New York Academy of Medicine
2004
Children's Memorial Health Institute
2000
Glutathione peroxidase 2 (Gpx-2) is a selenoenzyme with antioxidant capabilities that may play role in cancer development. Hence, we investigated the immunohistochemical expression of Gpx-2 protein colon adenocarcinoma samples derived from patients who did not receive any form treatment prior to surgical procedure. The associations between and clinical parameters were analysed using Chi2 test Fisher's exact test. A Kaplan-Meier analysis log-rank used verify relationship intensity 5-year...
Introduction: Lichen sclerosus (LS) is a chronic skin and mucosa inflammatory disease. It affects mainly the female anogenital area especially in postmenopausal period. The main symptoms include pruritus, burning, pain, sometimes urinary problems, or difficulties defecation. Usually, porcelain-white plaques are seen mucosa. etiology pathogenesis of LS still uncertain. There some research studies on possible genetic predisposition, yet autoimmune, hormonal, infectious factors not excluded....
There is sufficient evidence that blood group related Lewis antigens are tumor-associated molecules. We have conducted immunohistochemical analysis of the expression in breast cancer tissue as an indicator degree malignancy and a prognostic factor. The studies were performed by examining 43 female patients diagnosed with invasive ductal carcinoma breast. Postoperative specimens stained immunohistochemically using panel monoclonal antibodies (MAbs) specific for antigens: sialosyl LewisA,...
The aim of this study is to assess late results surgical treatment for primary non-Hodgkin lymphoma (PNHL), thyroid sarcomas (TS) and tumour metastases (TM) the gland.Between January 1st, 1990 December 31st, 2005, 12725 patients were surgically treated various types goitre. Malignant was diagnosed in 617 (4.9%) cases, consisting 597 (96.8%) with carcinoma 20 (3.2%) other tumours, which included 9 (1.5%) cases PNHL, TM 2 (0.2%) who showed TS.In group variant B-cell predominated (77.8%), renal...
Colorectal cancer (CRC) is the third and second most commonly diagnosed worldwide in males females, respectively. Despite prominent progress diagnosis treatment, recurrence rates are still high. A tumour hypoxic environment leads to an increase glycolytic metabolism. The crucial intermediate component of glycolysis, glyceraldehyde-3-phosphate dehydrogenase (GAPDH), could play a significant role progression. An increased level GAPDH has been described oncogene-induced transformation...
There are differences in the histological diagnostic criteria for early stage gastrointestinal carcinoma between Western and Japanese pathologists. of "presence stromal invasion neoplastic cells", while "the degree cytological structural abnormality cells, regardless invasion". The aim present study is to clarify review status esophageal squamous cell (SCC) also their significance accuracy.Twenty-nine Polish, German, pathologists participated this study. A total 18 slides biopsy, endoscopic...
Abstract Primary melanomas in the gastrointestinal tract are extremely rare, with an estimated prevalence of 0.5 to 1 case per million. mucosal gastric origin account for approximately 1–3% all primary tract. We present a patient who underwent surgery due melanoma.
In the process of evolution a number complicated mechanisms have developed to protect gastric mucous membrane, e.g., angiogenesis and stimulation mucosal growth. The aim this study was determine role vascular endothelial growth factor (VEGF) administered intraperitoneally in gastroprotective response stress-induced acute ulcers rats. A dramatic increase blood vessels observed when VEGF injected 24 h before stress exposure. Gastric secretion, depth ulceration index decreased significantly...
Background.Disturbances in pancreatic microcirculation, beginning with vasoconstriction, are crucial early pancreatitis and progression to necrotizing pancreatitis.Thus, vascular-targeted treatment aiming restore a sufficient level of microcirculation through vasodilation would possibly reduce the severity pancreatitis.Lidocaine is an anti-arrhythmic local anesthetic drug, which also acts as vasodilator at higher concentrations. Objectives.To evaluate efficacy intra-arterial infusion...
The synchronous primary lung tumors is a rare condition and presented patient the first reported case of simultaneous two distinct neuroendocrine cancer lesions in same lobe. We present 55-year-old woman with right upper Initially she showed no signs or symptoms related to was admitted Thoracic Surgery Ward for investigation oval, solitary pulmonary nodules (11 19 mm diameter) detected on chest X-ray performed three months earlier. radiological imaging variability growth both (smaller tumor...
Abstract IThe present study outlines the case of a 30-year-old patient with central odontogenic fibroma. The tumour developed in alveolar process maxilla area 13–15. describes clinical symptoms, radiological image, treatment method and histopathological image tumour. also presents one-year period post-surgical observation.
(1) Background: Colorectal cancer (CRC) is the third most common in terms of incidence and mortality. Approximately 90% all colorectal cases are adenocarcinomas, originating from epithelial cells mucosa. Upregulated gene 4 (URG4) an oncogene involved development. The aim study was to assess immunohistochemical expression URG4 protein Polish patients with colon adenocarcinoma who were not treated any therapy before radical surgery. (2) Methods: used tissue samples taken people a confirmed...
The coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), evolved into a global pandemic. As ACE2 on the surface of alveolar cells lung epithelium is one potential target receptors for SARS-CoV-2, respiratory symptoms are most common presentation COVID-19. aim our study was to investigate morphological findings in tissue after being infected SARS-CoV-2 and compare histopathologic changes patients with COVID-19 infection history who died...
Immunohistochemical assessment of proliferation marker – Ki67 in nasal polyps tissue and healthy mucosa was performed. There no statistically significant difference between percentage positive cells mucosa. These were observed mainly epithelial layer few subepithelial layer. In examined group expression higher planoepithelial metaplasia. Assessment processes could be sensitive early indicator neoplasmatic transformation. Examined subgroup which also higher, with eosinophilic infiltrations....
Introduction: Bronchopulmonary (BP) carcinoids are low and intermediate grade tumors, seen in adults between fourth to sixth decade, where no clear association with tobacco smoking is established. Most often they sporadic lesions (95%). Half of patients have symptoms the tumor incidentally found on a chest x- ray. BP good prognostic, however there risk distant metastasis recurrences frequent. Therefore crucial role vigilant follow- up, extending far beyond 5 years. Case presentation: We...
Adenomatous polyps (AP) of the gastrointestinal tract in children are very rare. Because their potential malignancy, they great clinical importance. There is little experience management with AP. The immunohistochemical expression Lewis blood group antigens (BGA) (sialosyl-Lea, Lea, Leb, Lex, and Ley) number activated nucleoli silver staining method for nucleolar organizer regions (AgNORs) were studied two In a girl isolated AP stomach colon, it was found that Leb s-Lea expressed extensively...