A5063528727- Head and Neck Cancer Studies
- Voice and Speech Disorders
- Tracheal and airway disorders
- Ear and Head Tumors
- Cancer-related molecular mechanisms research
- Asthma and respiratory diseases
- Sinusitis and nasal conditions
- Salivary Gland Tumors Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Dysphagia Assessment and Management
- Protease and Inhibitor Mechanisms
- Respiratory and Cough-Related Research
- Cancer-related Molecular Pathways
- RNA modifications and cancer
- Peptidase Inhibition and Analysis
- Allergic Rhinitis and Sensitization
- Ferroptosis and cancer prognosis
- Otitis Media and Relapsing Polychondritis
- DNA Repair Mechanisms
- Cancer, Lipids, and Metabolism
- Ear Surgery and Otitis Media
- Tumors and Oncological Cases
- Olfactory and Sensory Function Studies
- COVID-19 and healthcare impacts
- Kruppel-like factors research
Medical University of Lodz
2016-2025
Uniwersytecki Szpital Kliniczny w Opolu
2005-2018
Polskie Towarzystwo Gastroenterologii
2013
As online health information-seeking surges, concerns mount over the quality and safety of accessible content, potentially leading to patient harm through misinformation. On one hand, emergence Artificial Intelligence (AI) in healthcare could prevent it; on other questions raise regarding medical information provided. laryngeal cancer is a prevalent head neck malignancy, this study aims evaluate utility three large language models (LLMs) as sources about cancer.
Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes implicated in the invasion and metastasis many kinds cancer because their ability to degrade components extracellular matrix. Specific tissue inhibitors matrix (TIMPs) regulate activity. MMPs TIMPs were identified neoplasm, including cancers head neck, lung, breast colon cancer. In most researches strong relation between expression clinical course disease was observed, although there discrepancies authors. The aim this...
The incidence of head and neck cancer (HNC) has significantly increased over the past two decades. Material methods: This study analyzed trends in HNC mortality using data from Polish Cancer Register (1999–2021) across three age cohorts (60–69, 70–79, 80+) projected through to 2035. Statistical analyses included regression, correlation, parallelism tests, with significance levels α = 0.05 Bonferroni correction applied (αc ≈ 0.017). Results: In 60–69 cohort, rates faster than (p < 0.001),...
Background: This study aimed to investigate the relationships between kymographic parameters derived from high-speed videoendoscopy (HSV) and simultaneously recorded acoustic signals. The research provides insights into vibratory dynamics of various glottal pathologies, assessed across different widths, their mutual relations with audio data. Methods: included 192 participants categorized as normophonic or having functional organic lesions (benign, premalignant, malignant). Parameters...
Advancements in dynamic laryngeal imaging, particularly high-speed videoendoscopy (HSV), have addressed several limitations of laryngovideostroboscopy (LVS). This study aimed to compare the success rates LVS and HSV generating recordings suitable for objective functional assessment vocal fold movements. Methods: included 200 patients with voice disorders (123 benign glottal lesions, 56 malignant 21 disorders) 47 normophonic individuals. All participants underwent followed by HSV. Kymographic...
Head and neck cancer (HNC) shows a "diverging scissors" pattern, with incidence mortality linked to regional economic status. We aim investigate whether socioeconomic disparities between regions correlate widening gaps in HNC rates, particular emphasis on age-related patterns among elderly populations. Cross-sectional study. Data from the National Cancer Registry for females 2003 2019. 76 649 patients, 49 858 males, 26 791 2019 age cohorts: 60-69, 70-79, 80+, covering all voivodeships...
Abstract Background The genes of base excision repair (BER) pathway have been extensively studied in the association with various human cancers. We performed a case-control study to test between two common single nucleotide polymorphisms (SNPs) XRCC1 gene head and neck squamous cell carcinoma (HNSCC). Methods genotype analysis Arg194Trp Arg399Gln for 92 HNSCC patients 124 controls cancer free subjects, Polish population were using PCR-based restriction fragment length polymorphism (PCR-RFLP)...
Abstract Purpose The study aimed to assess the relevance of objective vibratory parameters derived from high-speed videolaryngoscopy (HSV) as a supporting tool, assist clinicians in establishing initial diagnosis benign and malignant glottal organic lesions. Methods HSV examinations were conducted 175 subjects: 50 normophonic, 85 subjects with vocal fold lesions, 40 early glottic cancer; lesions confirmed by histopathologic examination. parameters, kymography: amplitude, symmetry, dynamic...
The management of Vocal Fold Leukoplakia (VFL) remains problematic. There is no consensus on the indications or timing for surgery. objective was to select most accurate classification predicting low- and high-risk VFL in White Light Imaging (WLI) Narrow Band (NBI) establish a diagnostic algorithm with timely referral treatment. A total 259 patients were included study; 186 lesions classified as low-grade 110 high-grade dysplasia. results WLI acc. two-tier three-tier Chen 2019...
Abstract The paper aims to define the variables that elevate risk of VFL recurrence after adequate primary treatment, and present Recurrence Risk Model with practical conclusions handle pVFL rVFL. Out 207 patients vocal fold leukoplakia (pVFL), in 41 (19.8%) recurrent (rVFL) was diagnosed. All were assessed by using a trans-nasal flexible video-endoscope white light, NBI. measure our study investigate whether morphological features WL, vascular pattern NBI, histological findings could...
The accessory parotid gland (APG, Vth level) differs in histological structure from main tissue. This gives rise to the hypothesis, mirrored clinical observations, that representation of tumours is different than rest gland. aim study was analyse epidemiological and differences located regions I–V, with particular emphasis on distinctiveness region V. To define factors will indicate risk malignancy clinically benign appearance, multicentre prospective studies conducted between 2017–2021 by...
Allergic rhinitis (AR) is the most common form of allergy, which - as epidemiological research has shown applies to nearly 25% population. AR significantly affects quality life patient, and more severe disease, greater risk developing bronchial asthma. One factors affecting severity symptoms degree their control air pollution. In some patients, despite proper treatment, persistence or only partial remission (uncontrolled allergic rhinitis) observed. This can lead an increase in comorbidities...
Introduction: One of the most recent methods used in imaging larynx is narrow band (NBI). NBI enables us to detect specific patterns pathological angiogenesis suggestive premalignant or neoplastic lesions. The aim study was compare laryngeal lesions white light endoscopy (WLE) and relation histopathological examination. Material methods: 333 patients with underwent endoscopic evaluation WLE NBI. Sensitivity, specificity, positive negative predictive value (PPV, NPV) for were calculated....
This is the first study assessing clinical management of severe, isolated dysphonia during post-COVID-19 syndrome. One hundred and fifty-eight subjects met inclusion criteria for condition as specified by WHO. Six patients were diagnosed with severe dysphonia, constituting 3.8% initial group. The pre- post-examination protocol consisted subjective voice self-assessment routine laryngological examination, followed an instrumental examination means Laryngovideostroboscopy (LVS) High-Speed...
To present outcomes of extensive surgery: lateral, subtotal, total petrosectomies in patients with temporal bone invasion resulting from specific primary cancers.Retrospective case review.Four tertiary referral centers.89 cancer the treated between January 2006 and December 2010.Multidisciplinary team approach including surgical resection, reconstruction, postoperative radiotherapy.Disease-specific survival, overall survival.In 27.0% patients, relapse was reported, an average 6.3 months...
Introduction: Standard treatment for pleomorhic adenoma (PA) of the parotid gland is complete surgical excision. Radiotherapy (RT) as a primary method controversial and generally not applied. However RT might be considered an adjuvant therapy in some selected cases. Aim: Aim this work was to define recommendations patients with PA after Methods: Based on results currently published literature authors' own experiences from leading Polish laryngological oncological clinical centers dealing...