It is crucial to find a balance between functional and oncological outcome when choosing an adequate method for the management of vocal fold leukoplakia. Therefore, detailed examination milestone in decision-making process.To examine whether narrow-band imaging (NBI) can be helpful assessment case leukoplakia how overcome "umbrella effect"- understood as submucosal vascular pattern hidden under plaque.Prospective cohort 41 consecutive patients. Inclusion criteria: leukoplakia, no previous...

The management of Vocal Fold Leukoplakia (VFL) remains problematic. There is no consensus on the indications or timing for surgery. objective was to select most accurate classification predicting low- and high-risk VFL in White Light Imaging (WLI) Narrow Band (NBI) establish a diagnostic algorithm with timely referral treatment. A total 259 patients were included study; 186 lesions classified as low-grade 110 high-grade dysplasia. results WLI acc. two-tier three-tier Chen 2019...

Abstract The paper aims to define the variables that elevate risk of VFL recurrence after adequate primary treatment, and present Recurrence Risk Model with practical conclusions handle pVFL rVFL. Out 207 patients vocal fold leukoplakia (pVFL), in 41 (19.8%) recurrent (rVFL) was diagnosed. All were assessed by using a trans-nasal flexible video-endoscope white light, NBI. measure our study investigate whether morphological features WL, vascular pattern NBI, histological findings could...

Trans-oral laser microsurgery is an established technique for the treatment of early and moderately advanced laryngeal cancer.The authors intend to test usefulness narrow-band imaging in intraoperative assessment larynx mucosa terms specifying surgical margins.Forty-four consecutive T1-T2 glottic cancers treated with trans-oral Type I-VI cordectomy were presented. Suspected areas (90 samples/44 patients) biopsied under guidance white light sent frozen section.Our study revealed that 75 90...

Recurrent respiratory papillomatosis (RRP) is a benign disease caused by human papillomavirus 6 and 11. The characteristic feature of this are wart-like lesions covering the epithelium with predilection for larynx. There no curative treatment disease. goal total surgical removal papillomatous in order to reduce number relapses. Therefore, good visualization method papillomas crucial during surgery. aim study was compare accuracy narrow band imaging (NBI) use white light alone detecting...

Background The prognostic value of positive surgical margins after transoral laser microsurgery (TOLM) is still under debate. In case superficial margins, some experts recommend a second-look surgery (SL) and wait watch approach with close observation. Narrow band imaging (NBI) an advanced system used to enhance visualization mucosal vascular pattern. laryngology, NBI improve the detection premalignant, dysplastic malignant lesions. Aim To assess usefulness in guiding clinical decision...

<b>Introduction:</b> A Polish National Major Salivary Gland Benign Tumors Registry (SGR) is a report of benign salivary gland neoplasms (SGNs) from 26 different centres in Poland, introduced 2014. The aim this study to analyze demographic characteristics and clinico-pathological factors SGNs treated large tertiary institutions determine possible correlations between selected variables. <br><b>Material method:</b> Analysis 585 patients recorded SGR operated on...

Abstract Laryngeal granulomas belong to common complications following trans-oral laser microsurgery (TLM). The aim of this study was evaluate NBI in the differentiation between granuloma-like lesions and local tumor recurrence. 154 consecutive patients after TLM due early laryngeal cancer were enrolled. In group, a monthly follow-up including endoscopy performed. Moderate severe dysplasia, carcinoma situ invasive defined as positive histology, granuloma other benign negative histology...

The miRNA-196a2 has shown significance in the development of various neoplasms, including head and neck squamous cell carcinoma (HNSCC). oncogenic functionality this miRNA is mediated via its potential to target annexin A1 mRNA, a tumor suppressor gene involved inhibition NF-κB pathway. Interestingly, recent data indicate susceptibility for aforementioned neoplasms patients with CC genotype vs CT TT genotypes rs11614913 SNP located within DNA sequence miR-196a2 that results elevated...

Objective The main goal was to compare the clinical data of patients with T1 and T2 glottic cancer treated CO 2 transoral laser microlaryngoscopy (TLM) in Tertiary Referral University Department Otolaryngology, Head Neck Surgery, Poznan local Oncology Maxillofacial Bydgoszcz. Material Methods Unified databases for 7‐year period January 2005–December 2011 were created these two cohorts. database contained 341 patients: 231 from tertiary center 110 department, which 298 (87%) men, 43 (13%)...

Discerning the preoperative nature of vocal fold leukoplakia (VFL) with a substantial degree certainty is fundamental, seeing that histological diagnosis VFL includes wide spectrum pathology and there no consensus on an appropriate treatment strategy or frequency surveillance. The goal our study was to establish clear schedule diagnostics decision-making in which timing necessity surgical intervention are crucial not miss this cancer hidden underneath white plaque.We define as combination...

Background Surgery, the treatment of choice for parotid pleomorphic adenoma (PA), is associated with facial nerve palsy and decreased quality life. Re-operation PA recurrence (rPA) significantly increases these risks constitutes a dilemma both patient surgeon. Factors influencing success re-operation, as well self-reported satisfaction sides, have yet to be addressed in literature. This study aims improve upon decision-making schedule re-operations, based on expectations, imaging,...

Recurrent respiratory papillomatosis is a long-term disease caused by HPV 6 and 11, but there still noconsensus on the factors that may influence its course.

<b><br>Introduction:</b> Immune checkpoint inhibitors (ICIs) and T-cell therapies are a modern, well-established cancer treatment. The priority of oncological treatment is to cure cancer. However, treatment-related toxicities, i.e. immune-related adverse events (irAEs), continue emerge not that well understood yet. ICIs can cause profound, multiple, diverse irAEs - the sequelae unknown mechanisms. One organs susceptible collateral damage hearing organ. Complications related...

To investigate the impact on local relapse rate (LRR) and disease specific survival (DSS) of intraoperative margins (FS) obtained by circumferential sampling method, corresponding to lesion shape marked using clock-face orientation combined with narrow band imaging (NBI) in head neck squamous cell carcinoma Materials Methods: 147 consecutive patients who underwent primary surgery radical intent for oral oropharyngeal cancer between 2011 2016 were prospectively enrolled. Patients assigned 3...

The coincidence of an idiopathic unilateral vocal fold paresis and hereditary hemorrhagic telenagiectasia (HHT) is extremely rare has not been described in the available literature yet.A 55-year-old female was admitted to hospital due acute onset hoarseness, voice fatigue, effort dyspnea. In past, patient diagnosed with HHT on admission presented characteristic vascular lesions oral cavity. She reported also experiencing a moderate epistaxis at least once per month.The otolaryngological...

<br><b>Introduction:</b> The taxonomy of vocal fold lesions has been refined, and it serves as a common descriptive language for diagnosis, treatment algorithms, reporting outcomes. However, we observe rare cases when numerous pathologies overlap, resulting in an unclear complicated clinical presentation the glottis.</br> <br><b>Aim:</b> aim this paper is to present overlapping etiopathological factors which poses challenge making diagnosis referring...

<br><b>Introduction:</b> Bell's palsy is still the diagnosis of exclusion. In most patients it does not progress, unilateral, and selflimiting. Additionally, majority recover spontaneously within 3 weeks. It well known that all with irreversible facial nerve paresis (FNP) need further examinations to exclude organic, infectious, metabolic, autoimmunological causes palsy. The goal study was assess frequency malignancies hidden under "Bell's palsy".</br>...

Cholesteatoma is a pathological tissue that may extend into all parts of temporal bone and rarely, as this study highlights, beyond its structures. Nevertheless, the spread outside mastoid tip soft tissues neck or parotid space very rare. The case 23-year-old male with right mass presented. patient had history (2006, 2009, 2012) three tympanoplastics for recurrent ear cholesteatoma. tumor was revealed incidentally in magnetic resonance imaging January 2016, but inconclusive. After 6 months,...