Maciej Misiołek

ORCID: 0000-0002-8476-9153
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About
Contact & Profiles
Research Areas
  • Tracheal and airway disorders
  • Voice and Speech Disorders
  • Sinusitis and nasal conditions
  • Head and Neck Cancer Studies
  • Head and Neck Surgical Oncology
  • Salivary Gland Tumors Diagnosis and Treatment
  • Head and Neck Anomalies
  • Oral and Maxillofacial Pathology
  • Airway Management and Intubation Techniques
  • Cancer Diagnosis and Treatment
  • Dysphagia Assessment and Management
  • Nasal Surgery and Airway Studies
  • Vestibular and auditory disorders
  • Meningioma and schwannoma management
  • Asthma and respiratory diseases
  • Hearing, Cochlea, Tinnitus, Genetics
  • Neuroscience of respiration and sleep
  • Urticaria and Related Conditions
  • Obstructive Sleep Apnea Research
  • RNA modifications and cancer
  • Hearing Loss and Rehabilitation
  • Nutrition and Health Studies
  • Noise Effects and Management
  • Allergic Rhinitis and Sensitization
  • Bone Tumor Diagnosis and Treatments

Medical University of Silesia
2016-2025

University of Silesia in Katowice
2016-2025

The Maria Sklodowska-Curie National Research Institute of Oncology
2016-2023

Creative Commons
2023

Górnośląskie Centrum Medyczne
2007-2020

Jan Długosz University
2013

Centrum Onkologii
2012

Silesian Center for Heart Disease
1994-2010

Ente (Poland)
2009

Szpital Kliniczny Dzieciątka Jezus
2002-2007

Abstract Background Chronic spontaneous urticaria (CSU) is an immune-inflammatory disease, characterized by acute phase response (APR) and immune activation. There has been increasing evidence showing that vitamin D deficiency/insufficiency associated with increased incidence and/or severity of disorders. Aim To assess relationship between status C-reactive protein (CRP), a nonspecific inflammatory marker CSU activity. Methods Concentrations CRP 25-hydroxyvitamin [25(OH)D], biomarker were...

10.1186/1476-9255-11-2 article EN cc-by Journal of Inflammation 2014-02-03

AbstractThe efficacy and safety of amoxycillin/clavulanic acid (AMX/CA) (875/125mg b.i.d. for 14 days) were compared with that cefuroxime axetil (500mg in a multicenter, open, parallel-group, randomized clinical trial 206 adults chronic or acute exacerbation sinusitis. Clinical response was similar, 95% AMX/CA-, 88% cefuroxime-treated, clinically evaluable patients cured (95% confidence interval; -0.6% to +15%). In bacteriologically patients, cure rates, defined as eradication the original...

10.1179/joc.2002.14.5.508 article EN Journal of Chemotherapy 2002-01-01

Chronic spontaneous urticaria (CU) is associated with activation of the acute phase response (APR). Nevertheless, APR-associated proteins have not been well characterized as potential biomarkers disease severity. To assess pattern complement C3 and C4 – reactants in patients CU. C3, CRP concentrations were measured serum 70 showing different degrees urticarial severity 33 healthy subjects. Serum significantly increased CU compared subjects exceed normal lab range by about 5% 10%,...

10.1186/1476-9255-10-22 article EN cc-by Journal of Inflammation 2013-01-01

Background . The platelet parameters and C-reactive protein (CRP) are markers reflecting a systemic inflammatory response. Among those, CRP is one of the major proteins helpful in determination severity/activity chronic spontaneous urticaria (CSU). Aim To determine relationships between activation indices serum concentration CRP, best marker acute phase response, their potential clinical use CSU patients. Methods Mean volume (MPV), distribution width (PDW), count as well were measured...

10.1155/2014/650913 article EN BioMed Research International 2014-01-01

Our previous findings showed the importance of analysing peripheral markers acute phase response (APR) activation, C-reactive protein (CRP) and IL-6 in context urticaria activity severity. However, these biomarkers do not reliably differentiate between APR to infectious disease severity.In order investigate a possible association immune-inflammatory activation CRP procalcitonin (PCT).Serum PCT concentrations were measured patients with CU varying severity as well healthy subjects.Serum...

10.1007/s00011-012-0580-1 article EN cc-by Inflammation Research 2012-12-02

Local allergic rhinitis (LAR) is found in some patients with typical symptoms but who have negative skin prick tests and IgE to aeroallergens while presenting positive nasal provocation for proper allergens. Little information about the clinical characteristics prevalence of LAR has been published. The aim this study was determine chronic rhinitis.In total, 680 out 3400 pre-screened subjects were at least 5 years old included from 17 sites Poland protocol. following medical history...

10.4193/rhin18.137 article EN Rhinology Journal 2019-02-01

The purpose of the study was to assess burnout levels in nurses ( N = 161) versus physicians 373). were evaluated by Polish adaptation Spanish Burnout Inventory (Cronbach’s alpha > .70). High level found 18.63 percent and 12.06 anesthesiologists, critical 3.74 5.90 anesthetists. There statistically significant differences global score, Enthusiasm toward job, Psychological exhaustion, Indolence subscales between physicians. No sexes any variable.

10.1177/1359105315604377 article EN Journal of Health Psychology 2015-10-02

The study was a prospective, double-blind, placebo-controlled trial with patients diagnosed LAR to HDMs and concomitant asthma who underwent 12-month treatment course of SLIT for HDM allergies. Seventeen were randomized the use allergen extracts D. pteronyssinus farinae (50/50%) in SQ-HDM tablets 15 placebo group. total rhinitis score (TRSS), symptom (TASS), combined (TSS), medication (TMS), FEV1 analyzed.Results: In final analysis, 16 received 14 completed protocol included. Significant...

10.1080/02770903.2021.1971701 article EN Journal of Asthma 2021-08-25

Active chronic urticaria, identified as a mast cell- and basophil-dependent inflammatory disorder of the skin is able to elicit acute phase response (APR). However, systemic in different types urticaria poorly characterized.To determine APR pattern clearly defined group patients with and/or angioedema - induced by NSAIDs.Plasma IL-6 serum C-reactive protein (CRP) concentrations were studied 17 NSAIDs-induced urticaria/angioedema (NSAIDsAU) 20 healthy controls. Eleven who used NSAIDs...

10.1111/j.1468-3083.2012.04486.x article EN Journal of the European Academy of Dermatology and Venereology 2012-02-21

Low grade inflammation is associated with both chronic spontaneous urticaria (CSU) and atherosclerosis. Data regarding an association between urticarial atherosclerosis subsequent cardiovascular events are scarce. It has been demonstrated that matrix GLA protein (MGP), a biomarker of arterial calcification, increased in patients To evaluate circulating levels markers calcification acute phase response (APR) CSU. Concentrations MGP IL-6 were measured venous blood samples long-lasting...

10.1684/ejd.2014.2474 article EN European Journal of Dermatology 2015-01-01

There is still controversy regarding the influence of aging on medial olivocochlear (MOC) system function. The main objective this study to measure age-related changes MOC function in people with normal hearing thresholds.Bilateral assessment effect for click-evoked otoacoustic emissions (CEOAEs; at 70±3 dB peak sound pressure level [pSPL], click 50/second, 260 repeats, 2.5-20 millisecond window) and distortion product (DPOAEs; [frequencies] f2/f1=1.22, [levels primary tones] L1=65 SPL L2=55...

10.2147/cia.s61934 article EN cc-by-nc Clinical Interventions in Aging 2014-06-01
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