A5022131042- Head and Neck Cancer Studies
- Immune Cell Function and Interaction
- Cancer-related Molecular Pathways
- Immunotherapy and Immune Responses
- Ear Surgery and Otitis Media
- RNA modifications and cancer
- Medical Imaging Techniques and Applications
- Sinusitis and nasal conditions
- Cancer Immunotherapy and Biomarkers
- Cancer Diagnosis and Treatment
- Tracheal and airway disorders
- Radiomics and Machine Learning in Medical Imaging
- Reconstructive Surgery and Microvascular Techniques
- Ear and Head Tumors
- Cancer-related gene regulation
- Reconstructive Facial Surgery Techniques
- Head and Neck Surgical Oncology
- Lymphoma Diagnosis and Treatment
- Immune cells in cancer
- Bone health and treatments
- Multiple and Secondary Primary Cancers
- Cell death mechanisms and regulation
- Voice and Speech Disorders
- Vascular Anomalies and Treatments
- Cancer-related molecular mechanisms research
Medical University of Lublin
2013-2024
Centrum Słuchu i Mowy
2020
Institute of Physiology and Pathology of Hearing
2020
Medical University of Lodz
2020
Polskie Towarzystwo Gastroenterologii
2013
Instytut Medycyny Wsi im. Witolda Chodźki
1991-2011
Lublin Oncology Center
2004
University of Economics and Innovation
1998
Pathology of the external and middle ear is most frequent reason to prescribe antibiotics perform surgery in children young adults. In majority cases imaging studies are not performed; need for comes when complications suspected or treatment effective. This paper discusses indications temporal bone presents pathological conditions, together with differential diagnosis, clinical symptoms methods treatment.This pictorial review describes major diseases, special regard findings appropriate...
Hereditary hemorrhagic telangiectasia (HHT) is a rare systemic fibrovascular dysplasia also known as Rendu-Osler-Weber disease. Epistaxis often the first and foremost symptom of disease recurrent epistaxis main complaint.Evaluation effectiveness safety endovascular treatment in HHT patients.Between June 2004 January 2008, 14 patients with underwent embolization external carotid artery (ECA) branches due to severe epistaxis. There were eight men six women aged 27-42 years. Patients referred...
(1) Background: the purpose of study was to assess relationship between cancer stage, selected immunological parameters, Epstein–Barr virus (EBV) infection, and total serum content iron, zinc, copper in patients with laryngeal (LC). (2) Methods: Fe, Zn, Cu were measured 40 LC 20 controls. Immunophenotyping peripheral blood lymphocytes performed by flow cytometry using fluorescent antibodies against CD3, CD4, CD8, CD19, CD25, CD69, PD-1. Tumor lymph node analyzed cytometry. EBV DNA quantified...
Naturally occurring coumarins are bioactive compounds widely used in Asian traditional medicine. They have been shown to inhibit proliferation, induce apoptosis, and/or enhance the cytotoxicity of currently drugs against a variety cancer cell types. The aim our study was examine antiproliferative activity different linear furanocoumarins on human rhabdomyosarcoma, lung, and larynx lines, dissolve their cellular mechanism action. were isolated from fruits Angelica archangelica L. or Pastinaca...
To present outcomes of extensive surgery: lateral, subtotal, total petrosectomies in patients with temporal bone invasion resulting from specific primary cancers.Retrospective case review.Four tertiary referral centers.89 cancer the treated between January 2006 and December 2010.Multidisciplinary team approach including surgical resection, reconstruction, postoperative radiotherapy.Disease-specific survival, overall survival.In 27.0% patients, relapse was reported, an average 6.3 months...
Abstract Purpose Evaluation of the utility free anterolateral thigh flap reconstruction defects resulting from radical temporal bone resection in management lateral skull base malignancies a single institution. Methods An analysis 17 en bloc subtotal petrosectomies for removal malignant tumours was performed. There were 12 squamous cell carcinomas, 4 basal carcinomas and 1 adenoid cystic carcinoma. The staged with University Pittsburgh TNM system. In all patients, preservation petrous apex...
Homeostasis in the body is maintained by multiple processes, including balance between formation of new cells and their dying. This paper describes mechanism pathways apoptotic cell death, phenomenon necrosis autophagy. Furthermore, it rarely presented types namely mitotic catastrophe, oncosis pyroptosis. The course these processes varies, as emphasized paper, on one hand connected with maintaining stability tissues physiological but other death are induction progression pathological...
A quick and reliable method for the evaluation classification of two types tissues is presented. Several chemometric methods were applied to evaluate multivariate data tissue samples with respect content trace elements. The Pb, Al, Zn, Cd, Cu, Ni Co was determined in healthy cancerous obtained from 26 patients. Determination done at milligram/kilogram level inductively coupled plasma optical emission spectrometry (ICP-OES) atomic absorption spectroscopy (AAS) techniques. Contents metals...
<b>Introduction:</b> Head and neck cancer (HNC) incidence mortality have increased significantly among the elderly in Poland over last two decades. This trend reflects challenges of an aging population underscores need for specialized care seniors.<b>Aim:</b> The study aimed to analyze morbidity HNC (ages 60–69, 70–79, 80+) between 1999 2021, predict trends until 2035, emphasizing dynamics 80+ age group.<b>Material methods:</b> Data from Polish National...
Multislice computed tomography (MSCT) virtual endoscopy was useful in evaluating mainly post-traumatic and postoperative cases. In other pathological conditions axial images MPR reformations were most useful.Evaluation of cross-sectional images, multiplanar 2-D reformations, 3-D reconstructions (VE) assessment the middle ear inflammatory diseases, trauma, otosclerosis tumours. Comparison each method correlation with surgical findings.Investigations carried out 80 patients pathology. case...
To assess the usefulness of delayed post-contrast computed tomography (CT) examination for detection residual or recurrent cholesteatoma after canal wall up tympanoplasty.This prospective, non-randomized study, set within an academic medical centre, included 17 consecutive patients who had undergone tympanoplasty cholesteatoma, with possible recurrence. Pre-contrast CT scans and images were compared second look surgical findings.A was found in eight at revision surgery correctly diagnosed on...
Background/Aim: The aim of this study was to analyze whether inhibition cyclooxygenase-2 by celecoxib and the subsequent enhancement in proliferation natural killer T (NKT) cells could play a role dendritic cell (DC)-based laryngeal cancer (LC) immunotherapy. Patients Methods: Peripheral blood mononuclear were obtained from 48 male patients diagnosed with LC 30 control without disease. Neoplastic lysate preparations made tissues after surgery used for vitro DCs generation. NKT assay...
The aim of this study was to assess head and neck squamous cell cancer surrounding tissue in computed tomography contrast enhanced perfusion studies, examine the role imaging depiction infiltration.We prospectively evaluated 43 primary malignant tumors, using standard CT followed by perfusion. Blood flow, blood volume, mean transit time, permeability values were obtained regions interest (ROIs) over lesions tissue. Results compared with histological analysis resected Sensitivity,...
Graves’ disease (GD) is an autoimmune that affects the thyroid. The development of autoimmunity associated with innate immune responses where prominent role plays Toll-like receptors (TLRs). aim our study was to assess relationship between expression levels TLR-2 and TLR-4 on CD4+ CD8+ T as well CD19+ B lymphocytes in patients GD selected clinical parameters. group consisted 32 women GD, control 20 healthy women. Immunophenotyping performed using flow cytometry cytokines concentrations were...
Multicenter evaluation of the quality life and hearing after Nucleus® cochlear implant placement in patients over 60 years age.Evaluation was performed receiving implants age as a part Cochlear-Implanted Recipient Observational Study (Cochlear-IROS). This study is prospective, international long-term assessment which enables observation recipients for up to three implantation. Data regarding subjective were gathered before first switch-on sound processor one year afterwards. Standardized...