A5086068979- Immune Cell Function and Interaction
- Immune Response and Inflammation
- Immunodeficiency and Autoimmune Disorders
- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Chronic Lymphocytic Leukemia Research
- Helicobacter pylori-related gastroenterology studies
- Gut microbiota and health
- T-cell and B-cell Immunology
- Cancer Immunotherapy and Biomarkers
- Lymphoma Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
- Antimicrobial Peptides and Activities
- Pressure Ulcer Prevention and Management
- Oral microbiology and periodontitis research
- IL-33, ST2, and ILC Pathways
- Immunotherapy and Immune Responses
- Dental Implant Techniques and Outcomes
- Wound Healing and Treatments
- Renal Diseases and Glomerulopathies
- Lung Cancer Research Studies
- Burn Injury Management and Outcomes
- Cutaneous lymphoproliferative disorders research
- Ferroptosis and cancer prognosis
- Iron Metabolism and Disorders
Medical University of Lublin
2021-2024
Endometriosis is a chronic, hormone-dependent disease characterized by the presence of endometrial tissue in ectopic locations. Since treatment options for this are still limited, and cure rate unsatisfactory, search ways to treat symptoms modify course key importance improving quality life patients with endometriosis. So far, literature has shown that nutrition can influence endometriosis through hormonal modification altering inflammatory or oxidative response. subject scientific research,...
The immune system protects against pathogens, and its dysfunction leads to primary secondary immunodeficiencies, increasing infection susceptibility. Epstein-Barr virus (EBV) reactivation is linked homeostasis disorders, particularly in common variable immunodeficiency (CVID) chronic lymphocytic leukemia (CLL). Toll-like receptor (TLR) pathways play a crucial role innate immunity, their deregulation may contribute dysfunction. This study aimed assess the impact of EBV on homeostasis,...
Objectives: This study aimed to assess the systemic and local inflammatory responses in patients with periimplantitis, focusing on key immune markers clinical parameters. The further explores relationship between markers, indices, dysregulation, particularly regarding T-cell exhaustion inflammation. Methods: A cohort of classified into moderate advanced stages, was compared a control group healthy individuals dental implants. Clinical parameters, including plaque index (API), bleeding...
Thyroid dysfunction and toxic metal exposure have been linked to the increased risk of autism spectrum disorders (ASD); however, relationship between those factors remains unclear. We aimed evaluate serum level hormones, namely thyroid-stimulating hormone (TSH), free triiodothyronine (fT3), thyroxine (fT4), urinary cadmium (U-Cd) manganese (U-Mn), in patients with ASD. The study group consisted 129 adolescents ASD, control 86 healthy persons. Ion chromatography spectrophotometric detection...
(1) Background: the purpose of study was to assess relationship between cancer stage, selected immunological parameters, Epstein–Barr virus (EBV) infection, and total serum content iron, zinc, copper in patients with laryngeal (LC). (2) Methods: Fe, Zn, Cu were measured 40 LC 20 controls. Immunophenotyping peripheral blood lymphocytes performed by flow cytometry using fluorescent antibodies against CD3, CD4, CD8, CD19, CD25, CD69, PD-1. Tumor lymph node analyzed cytometry. EBV DNA quantified...
Background: Non-small-cell lung cancer (NSCLC) is one of the most frequently diagnosed diseases among all types cancer. Infectious contribute to morbidity and mortality by delaying appropriate anti-cancer therapy in patients with NSCLC. Methods: The study aimed evaluate effectiveness vaccination 13-valent pneumococcal conjugate vaccine (PCV13) 288 newly NSCLC patients. analysis post-vaccination response was performed after assessing frequency plasmablasts via flow cytometry concentration...
(1) Background: Non-small-cell lung cancer (NSCLC) represents a significant global health challenge, contributing to numerous deaths. Despite advances in diagnostics and therapy, identifying reliable biomarkers for prognosis therapeutic stratification remains difficult. Toll-like receptors (TLRs), crucial innate immunity, now show potential as contributors development progression. This study aims investigate the role of TLR expression progression NSCLC. (2) Materials Methods: The was...
Periodontitis is a common oral condition that can have significant impact on the overall health of body. In recent years, attention has been paid to potential relationships between periodontitis and various hematological disorders. This publication aims present information available in literature this relationship, focusing examples red blood cell disorders (such as aplastic anemia sickle anemia) white cyclic neutropenia, maladaptive trained immunity, clonal hematopoiesis, leukemia, multiple...
Introduction: Toll-like receptors (TLRs) play a vital role in the innate immune response, recognizing pathogens and initiating inflammatory response. Research suggests that TLRs may also have significant impact on development progression of cancers, including gastric cancer (GC). Understanding individual immunopathogenesis provide new information necessary to develop more effective diagnostic therapeutic methods. Aim study: This study aimed determine selected TLR-2, -3, -4, -9 patients with...