Objectives: This study aimed to assess the systemic and local inflammatory responses in patients with periimplantitis, focusing on key immune markers clinical parameters. The further explores relationship between markers, indices, dysregulation, particularly regarding T-cell exhaustion inflammation. Methods: A cohort of classified into moderate advanced stages, was compared a control group healthy individuals dental implants. Clinical parameters, including plaque index (API), bleeding...

Periodontitis is a common oral condition that can have significant impact on the overall health of body. In recent years, attention has been paid to potential relationships between periodontitis and various hematological disorders. This publication aims present information available in literature this relationship, focusing examples red blood cell disorders (such as aplastic anemia sickle anemia) white cyclic neutropenia, maladaptive trained immunity, clonal hematopoiesis, leukemia, multiple...

Dental implantology is one of the most dynamically developing fields dentistry, which, despite clinical knowledge and new technologies, still associated with many complications that may lead to loss implant or development disease, including peri-implantitis. One reasons for this condition be fact dental implants cannot yield a proper osseointegration process due oral microbiota dysbiosis accompanying inflammation caused by immunological imbalance. This study aims present current as impact...

Abstract Among many substances used in clinical diagnosis, such as peripheral blood, gum homogenate, saliva and gingival pocket fluid, it is the latter that seems to bean extremely valuable diagnostic research material. Identification of mediators crevicular both healthy fissure, well pathological periodontal pockets can be a supplement initial diagnosis describe mechanism gumorperiodontal diseases. Changes concentration individual components fluid may assess severity disease. There are...

The paper presents the optimisation of a safe diode laser irradiation process applied to surface titanium implants in order reduce microbial numbers treatment inflammation classified as periimplantitis. study comprised isolation and identification microorganisms inhabiting surfaces dental implants, crowns, teeth saliva from patients with fully symptomatic Microorganisms were detected by culture-dependent method identified use MALDI-TOF mass spectrometry. isolated inoculated on new implant...

Introduction: Peri-implantitis is a serious complication in dental implantology that, if left untreated, may lead to implant loss and systemic diseases. Effective regeneration of bone defects resulting from peri-implantitis crucial maintaining the functionality implants. Purpose Study: The study aimed compare effectiveness fine-particle dentin Bio-Oss reconstruction caused by peri-implantitis. Materials Methods: included comprehensive radiological assessment changes density over time. Bone...

The paper presents the optimization of diode laser irradiation corroded dental implants in order to reduce number microorganisms associated peri-implantitis. research included identification on surface removed patients with peri-implantitis and assessment biocidal effectiveness against these microorganisms. Laser desorption/mass spectrometry (MALDI-TOF MS) was used identify metagens were examined by next generation sequencing (NGS). Irradiation performed a wavelength λ = 810, operating mode:...

The aim of this paper was to study the effectiveness a diode laser (LD) for removal microorganisms isolated from porcelain and zirconia crown surfaces used in implantoprosthetics order minimize infections around dental implants. In optimize biocidal efficacy process (at same time, avoiding increasing surface roughness during decontamination) effects doses were investigated. irradiation performed with at wavelength λ = 810 nm three variants different number repetitions (1 × 15 s, 2 3 s)....

Patients undergoing implant treatment are at risk of peri-implant bone loss, which is most often caused by the adverse effects microorganisms, but there few proven procedures for their reduction. The aim research was to identify microorganisms inhabiting composites used close screw access hole (SAH), compare them numerically with those present on surface crowns and teeth, optimize doses diode laser, will reduce not deteriorate roughness polished composites. were swabbed from SAH composites,...

The matter constituting the enamels of four types organisms was studied. variability ions presented in molar units. It proven that changes water contents enamel are significantly positively related to Mg; inversely, there is also a strong connection with Ca and P, main components bioapatite. organic has same positive characteristics coupled Mg contents. Amelogenins matter, which synthesize rods, likely have role adjusting amount Mg, thus establishing whole enamel; this adjustment occurs...

Abstract Periodontal disease is an inflammatory of multifactorial etiology. In order for it to appear there must come imbalance between the effects pathogens and host defense mechanisms. As a result its course destruction structures supporting teeth appears (periodontium, cement, bone), consequently leads loosening loss. recent years, participation RANKL/RANK/OPG in bone remodeling process was highligted. At molecular level resorption regulated through interaction ligand receptor activator...

Aim: The aim of this study is to demonstrate the possible correlation between expression examined protein markers - p53, EGFR, PCNA, p44/42 in mass tumor and clinical stage disease. Material: 48 patients Department Clinic Oral Maxillofacial Surgery, Lublin diagnosed with oral cancer. control group consisted 10 leukoplakia lesions cavity. methods: Immunohistochemical analysis using detection system DAKO K5007 Cat Dako REAL ™ Detection System, Peroxidase DAB +, Rabbit / Mouse. Results: Based...

Abstract In adult life, proper bone metabolism requires efficient regulation of formation and resorption processes. Bone turnover markers allow for assessing the rate menopausal period, female patients experience gradual reduction in blood estradiol levels. The deficit estrogens leads to enhanced osteoclastogenesis resorption. Alkaline phosphatase (ALP) is a membranebound enzyme that stimulates osteoblast activity mineralization. It synthesized by osteoblasts incorporated into newly formed...

Contemporary dental treatment primarily aims at the longest preservation of patient’s own dentition, provision proper function chewing, as well aesthetic requirements. According to literature, percentage successful endodontic is particularly high and ranges from 92-98%. One most frequent complications overfilling root canal. Sometimes material penetrates maxillary sinus or mandibular Here we describe a case gigantic extrusion into right detected by means CBCT examination. Gigantic canal can...

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Wstęp: Tradycyjne metody postępowania i wykonywania zabiegów z zakresu chirurgii stomatologicznej zazwyczaj prowadzą do bezpowrotnej utraty uzębienia powstania typowego ubytku wysokości szerokości kości grzbietu wyrostka zębodołowego. Celem niniejszego badania była ocena gojenia się ubytków kostnych po zastosowaniu materiału kościozastępczego Bio-Gen Mix.Materiały metody: Grupę badaną stanowiło 42 pacjentów leczonych powodu obecności torbieli zębopochodnych, zmian okołowierzchołkowych przy...

Gingivitis is accompanied by microorganisms, including pathogens, which must be eliminated to speed up the treatment of inflammation. Laser irradiation may one safe methods for reducing tissue contamination on tooth surface. The aim study was assessment surface in patients with gingivitis after use a diode laser eliminate microorganisms living there. In first stage research, were isolated (Candida albicans, C. guilliermondii, Escherichia coli, Haemophilus parainfluenzae, Klebsiella oxytoca,...

Abstract Apoptosis is a physiological process that occurs in the human body throughout entire life span. This can be seen tissues of stomatognathic system. A disorder such programmed cell death processes leads to development pathological lesions. Among these are inflammation, osteolytic lesions and neoplastic hyperplasia. We put forward future studies should concentrate on how use knowledge apoptotic their inhibitors therapeutic involving