Francesca deʼDonato
- Climate Change and Health Impacts
- Air Quality and Health Impacts
- Global Health Care Issues
- Thermoregulation and physiological responses
- Health disparities and outcomes
- Health, Environment, Cognitive Aging
- COVID-19 and healthcare impacts
- Infection Control and Ventilation
- COVID-19 impact on air quality
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 epidemiological studies
- Global Public Health Policies and Epidemiology
- Infrared Thermography in Medicine
- COVID-19 Pandemic Impacts
- Building Energy and Comfort Optimization
- Birth, Development, and Health
- COVID-19 Clinical Research Studies
- Urban Heat Island Mitigation
- Health, psychology, and well-being
- Maternal Mental Health During Pregnancy and Postpartum
- Occupational Health and Safety Management
- Atmospheric chemistry and aerosols
- Global Health and Surgery
- Healthcare and Environmental Waste Management
- Energy Load and Power Forecasting
ASL Roma
2018-2025
Azienda Sanitaria Locale Roma 3
2004-2024
Regional Health
2006-2024
Helmholtz Zentrum München
2023
Research Network (United States)
2021
Imperial College London
2018
Agenzia Regionale Parchi
2010-2018
Regione Lazio
2011-2016
National Centre for Disease Prevention and Control
2006-2013
Institut de Veille Sanitaire
2012
The present study aimed at developing a standardized heat wave definition to estimate and compare the impact on mortality by gender, age death causes in Europe during summers 1990-2004 2003, separately, accounting for duration intensity. Heat waves were defined considering both maximum apparent temperature minimum classified intensity, timing summer. effect was estimated as percent increase daily days compared non people over 65 years. City specific pooled estimates cause of calculated....
BackgroundExposure to cold or hot temperatures is associated with premature deaths. We aimed evaluate the global, regional, and national mortality burden non-optimal ambient temperatures.MethodsIn this modelling study, we collected time-series data on from 750 locations in 43 countries five meta-predictors at a grid size of 0·5° × across globe. A three-stage analysis strategy was used. First, temperature–mortality association fitted for each location by use regression. Second, multivariate...
Abstract Epidemiological analyses of health risks associated with non-optimal temperature are traditionally based on ground observations from weather stations that offer limited spatial and temporal coverage. Climate reanalysis represents an alternative option provide complete spatio-temporal exposure coverage, yet to be systematically explored for their suitability in assessing temperature-related at a global scale. Here we the first comprehensive analysis over multiple regions assess most...
Evidence on the potential interactive effects of heat and ambient air pollution cause-specific mortality is inconclusive limited to selected locations.We investigated cardiovascular respiratory its modification by during summer months (six consecutive hottest months) in 482 locations across 24 countries.Location-specific daily death counts exposure data (e.g., particulate matter with diameters ≤ 2.5 µm [PM2.5]) were obtained from 2000 2018. We used location-specific confounder-adjusted...
Older adults are generally amongst the most vulnerable to heat and cold. While temperature-related health impacts projected increase with global warming, influence of population aging on these trends remains unclear. Here we show that at 1.5 °C, 2 3 °C heat-related mortality in 800 locations across 50 countries/areas will by 0.5%, 1.0%, 2.5%, respectively; among which 1 5 4 deaths can be attributed aging. Despite a decrease cold-related due progressive warming alone, mostly counteract this...
Background The regional disparity of heatwave-related mortality over a long period has not been sufficiently assessed across the globe, impeding localisation adaptation planning and risk management towards climate change. We quantified global burden associated with heatwaves at spatial resolution 0.5°×0.5° temporal change from 1990 to 2019. Methods findings collected data on daily deaths temperature 750 locations 43 countries or regions, 5 meta-predictors in world. Heatwaves were defined as...
Background: Heat waves and air pollution are both associated with increased mortality. Their joint effects less well understood. Methods: We explored the role of in modifying heat on mortality, within EuroHEAT project. Daily meteorologic, data from nine European cities for years 1990–2004 were assembled. defined by taking intensity duration into account. The city-specific wave episodes estimated using generalized estimating equation models, adjusting potential confounders without inclusion...
Several studies have identified strong effects of high temperatures on mortality at population level; however, individual vulnerability factors associated with heat-related in-hospital are largely unknown. The objective the study was to evaluate using a multi-city case-crossover analysis.We studied residents four Italian cities, aged 65+ years, who died during 1997-2004. For 94,944 individuals in hospital and were hospitalised two or more days before death, demographics, chronic conditions,...
Abstract Background Standardized mortality surveillance data, capable of detecting variations in total at population level and not only among the infected, provide an unbiased insight into impact epidemics, like COVID-19 (Coronavirus disease). We analysed temporal trend excess deaths positive cases SARS-CoV-2 by geographical area (north centre-south), age sex, taking account deficit previous months. Methods Data from Italian rapid system was used to quantify during epidemic, estimate months...
Data from the rapid mortality surveillance system in 19 major Italian cities were used to carry out a timely assessment of health impact COVID-19 epidemic. By 18 April, + 45% excess was observed, with higher north country (+ 76%). The greatest among men, an increasing trend by age. Surveillance data can be evaluate lockdown and re-opening phases.
Minimum mortality temperature (MMT) is an important indicator to assess the temperature-mortality association, indicating long-term adaptation local climate. Limited evidence about geographical variability of MMT available at a global scale.We collected data from 658 communities in 43 countries under different climates. We estimated associations derive for each community using Poisson regression with distributed lag nonlinear models. investigated variation by climatic zone mixed-effects...
BackgroundIncreased mortality risk is associated with short-term temperature variability. However, to our knowledge, there has been no comprehensive assessment of the variability-related burden worldwide. In this study, using data from MCC Collaborative Research Network, we first explored association between variability and across 43 countries or regions. Then, provide a more picture global variability, gridded resolution 0·5° × were used assess at global, regional, national levels....
BackgroundClimate change can directly impact temperature-related excess deaths and might subsequently the seasonal variation in mortality. In this study, we aimed to provide a systematic comprehensive assessment of potential future changes variation, or seasonality, mortality across different climate zones.MethodsIn modelling collected daily time series mean temperature (all causes non-external only) via Multi-Country Multi-City Collaborative (MCC) Research Network. These data were during...
BackgroundExposure to cold spells is associated with mortality. However, little known about the global mortality burden of spells.MethodsA three-stage meta-analytical method was used estimate by means a time series dataset 1960 locations across 59 countries (or regions). First, we fitted location-specific, spell-related associations using quasi-Poisson regression distributed lag non-linear model period up 21 days. Second, built multivariate meta-regression between location-specific and seven...
This multicenter study is aimed at estimating changes in the effect of high temperatures on elderly mortality before and after 2003 heat waves following introduction prevention activities. A total sixteen cities were included study. City-specific relationships between maximum apparent temperature (MAT) daily (1998–2002) (2006–2010) intervention modelled through non-linear distributed lag models estimates combined using a random meta-analysis. We estimated percentage change for 3°C variations...
Evidence on the health effects of extreme temperatures and air pollution is copious. However few studies focused their interaction. The aim this study to evaluate daily PM10 ozone as potential effect modifiers relationship between temperature natural mortality in 25 Italian cities. Time-series analysis was run for each city. To interaction, a tensor product mean (lag 0–3) either or (both lag 0–5) defined estimates were extrapolated at low, medium, high levels pollutants. Heat estimated...
Assessing the association between temperature frequency and mortality can provide insights into human adaptation to local ambient temperatures. We collected daily time-series data on from 757 locations in 43 countries during 1979–2020. used a two-stage time series design assess all-cause mortality. The results were pooled at national, regional, global levels. observed consistent decrease risk of as normalized increases across globe. average increase comparing 10th 100th percentile was 13.03%...
Abstract The rising humid heat is regarded as a severe threat to human survivability, but the proper integration of into heat-health alerts still being explored. Using state-of-the-art epidemiological and climatological datasets, we examined association between multiple stress indicators (HSIs) daily mortality in 739 cities worldwide. Notable differences were observed long-term trends timing events detected by HSIs. Air temperature (Tair) predicts heat-related well with robust negative...
In February 2012 Italy was hit by an exceptional cold spell with extremely low temperatures and heavy snowfall. The aim of this work is to estimate the impact on health in Italian cities using data from rapid surveillance systems. Italy, a national mortality system has been operational since 2004 34 for monitoring daily mortality. Data were used evaluate shortly after occurrence event. Furthermore, cause-specific analysis conducted Roma Regional Mortality Registry emergency visits (ER)...