- Global Health Care Issues
- Climate Change and Health Impacts
- Air Quality and Health Impacts
- Health disparities and outcomes
- Dialysis and Renal Disease Management
- Chronic Disease Management Strategies
- Chronic Kidney Disease and Diabetes
- Health Systems, Economic Evaluations, Quality of Life
- Health, Environment, Cognitive Aging
- Long-Term Effects of COVID-19
- Blood Pressure and Hypertension Studies
- Renal Transplantation Outcomes and Treatments
- Cancer Immunotherapy and Biomarkers
- Dementia and Cognitive Impairment Research
- Employment and Welfare Studies
- Schizophrenia research and treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Emergency and Acute Care Studies
- Thermoregulation and physiological responses
- Immunotherapy and Immune Responses
- Cutaneous Melanoma Detection and Management
- Heart Failure Treatment and Management
- Healthcare Systems and Reforms
- Migration, Health and Trauma
- Environmental Justice and Health Disparities
ASL Roma
2016-2024
Azienda Sanitaria Locale Roma 3
2005-2024
Regione Lazio
2010-2024
Agenzia Regionale Parchi
2010-2024
Servizio Sanitario Nazionale
2020
Regional Health
2008-2016
Istituto Nazionale di Fisica Nucleare, Sezione di Napoli
2016
Istituti di Ricovero e Cura a Carattere Scientifico
2016
National Centre for Disease Prevention and Control
2006
Ministero della Salute
2005
The present study aimed at developing a standardized heat wave definition to estimate and compare the impact on mortality by gender, age death causes in Europe during summers 1990-2004 2003, separately, accounting for duration intensity. Heat waves were defined considering both maximum apparent temperature minimum classified intensity, timing summer. effect was estimated as percent increase daily days compared non people over 65 years. City specific pooled estimates cause of calculated....
Episode analyses of heat waves have documented a comparatively higher impact on mortality than morbidity (hospital admissions) in European cities. The evidence from daily time series studies is scarce and inconsistent.To evaluate the high environmental temperatures hospital admissions during April to September 12 cities participating Assessment Prevention Acute Health Effects Weather Conditions Europe (PHEWE) project.For each city, analysis was used model relationship between maximum...
Few studies have identified specific factors that increase mortality during heat waves. This study investigated socio-demographic characteristics and pre-existing medical conditions as effect modifiers of the risk dying waves in a cohort elderly residents Rome.A 651,195 aged 65 yrs or older was followed from 2005 to 2007. During summer, wave days were defined according month-specific thresholds maximum apparent temperature. The adjusted relative estimated using Poisson regression model...
This multicenter study is aimed at estimating changes in the effect of high temperatures on elderly mortality before and after 2003 heat waves following introduction prevention activities. A total sixteen cities were included study. City-specific relationships between maximum apparent temperature (MAT) daily (1998–2002) (2006–2010) intervention modelled through non-linear distributed lag models estimates combined using a random meta-analysis. We estimated percentage change for 3°C variations...
Understanding differences in survival across distinct subgroups of melanoma patients may help with the choice types therapy. Tumor-infiltrating lymphocytes (TILs) are considered a manifestation host immune response to tumor, but role TILs mortality is controversial. The aim this study was investigate independent prognostic factors for mortality. We carried out 10-year cohort on 4133 from same geographic area (Lazio) primary cutaneous diagnosed between January 1998 and December 2008....
The aim of the study was to identify sociodemographic and clinical factors associated with death after first lower-extremity amputation (LEA), minor major separately, using data from regional health administrative databases.
Since 2004, the Italian Department for Civil Protection and Ministry of Health have implemented a national program prevention heat-health effects during summer, which to-date includes 34 major cities 93% residents aged 65 years over. The represents an important example integrated approach to prevent impact heat on health, comprising Heat Watch Warning Systems, mortality surveillance system activities targeted susceptible subgroups. City-specific warning systems are based relationship between...
Background: The literature on air pollution exposure and Parkinson’s disease (PD) reported controversial results. aim of this study is to analyze the association particulate matter (PM 10 , PM 2.5 2.5–10 absorbance), nitrogen oxides (NO 2 NO x ), ozone (O 3 ) with incidence PD in a large administrative cohort. Methods: We followed 1,008,253 patients who are 50+-year-old residents Rome (free from PD) January 2008 December 2013. identified new cases using data several sources including drug...
Describing and monitoring socioeconomic inequalities in health are the prerequisite for planning equity policies. In Italy, some cities have integrated personal information from municipal registries with Census data healthcare systems to set up Longitudinal Metropolitan Studies (LMS). Under coordination of Italian National Institute Health, Migration, Poverty (NIHMP), six LMS network contributed present monograph: Turin, Venice, Reggio Emilia, Modena, Bologna, Rome. MORTALITY RESULTS....
Background: The identification of risk factors for SARS-CoV-2 infection and mortality in patients with dementia is a key aspect to support clinical decisions public health interventions. Objective: To assess the incidence COVID-19 related death cohort residing Lazio region investigate predicting both mortality. Methods: This population-based study used information from administrative databases surveillance system. Patients (age ≥65) were enrolled as December 31, 2019 followed-up until...
Termination of renal replacement therapy (RRT) is common in North America and Australia but considered to be rare Europe.In order review the phenomenon RRT termination all patients treated Newcastle upon Tyne between 1964 1993 a retrospective study clinical case notes was undertaken. In sex, age at start RRT, diagnosis history were recorded. addition, mortality data marital residential status recorded who died, Karnofsky index, bodyweight, complications, bereavement, place death, overall...
Objectives to investigate the association between real estate prices, education, and mortality. Design cohort study. Setting participants residents in Rome at 2011 Italian Census, not living institutions, address reported Census survey. People aged 18-99 years were followed from 2016 using anonymous record linkage procedures with administrative databases. The includes several individual information, such as gender, age, residential neighbourhood. Data cause of death collected mortality...
The aim of the present study was to analyse role potential selection processes and their impact when evaluating risk factors for 30-day mortality among patients hospitalised chronic obstructive pulmonary disease (COPD). A cohort 26,039 aged ≥35 yrs with COPD were enrolled. follow-up carried out using both cause register (CMR) hospital discharge (HDR). Individual associated studied outcomes. rate 1.21·1,000 patient-days −1 (95% confidence interval (CI) 1.14–1.29) CMR, 1.06·1,000 CI 0.98–1.13)...
Abstract Background Entering dialysis is a critical moment in patients’ healthcare journey, and little known about drug therapy around it. A study funded by the Italian Medicines Agency offered opportunity to leverage data from Lazio Regional Dialysis Transplant Registry (RRDTL) perform an observational on use patterns before after initiating chronic dialysis. Methods Individuals 2016–2020 were identified RRDTL, excluding patients with prior renal transplantation, stopping early, or dying...
Abstract Background Estimating CKD prevalence is difficult. Information on rather scanty in Italy and available figures come from surveys selected geographical areas. Administrative data have been already demonstrated to be an effective tool estimating the epidemiological burden of diseases, however there limited experience literature as far concerned. Methods The aim this study develop algorithm based regional Health Databases identify individuals with provide estimates disease Lazio Region...
Despite recommendations from associations of geriatric and psychiatry societies warnings drug agencies, antipsychotic (AP) drugs are frequently used to control behavioral psychological symptoms dementia. APs associated with a range potential adverse events, including increased risk cerebrovascular events mortality. Evidence suggests limited efficacy for aggression psychosis. Our objectives were investigate patterns predictors prescription among older adults dementia residing in large region...
Abstract Background The Emergency Department (ED) can be considered an indicator of accessibility and quality influenced in period economic downturns. In the last fifteen years, number migrants Italy has doubled (from 2.4 million 2005 to 5.2 2019, 4.1 8.7% total population, respectively). However, evidence about migrants’ healthcare use is poor, no studies focused on ED utilisation rate during Great Recession are available. This study aims analyse trends all-cause cause-specific among...
The factors associated with the inability to start hemodialysis an arteriovenous fistula (AVF) in chronic kidney disease patients are not fully understood.Evaluating type of vascular access at first and 1 year after it.The study cohort includes registered Regional Dialysis Transplant Registry Lazio undergoing between 2008 2015. Logistic regression models were used evaluate association socio-demographic, clinical care/organizational factors, hemodialysis. Cox assess odds switching AVF during...
. In the last decades some studies observed a moderate progressive decrease in short-term mortality incident hemodialysis patients. The aim of study is to analyse trends patients starting using Lazio Regional Dialysis and Transplant Registry.
Some studies have suggested that sun exposure plays a protective role in melanoma survival. This created paradox as the known carcinogen can act cancer promoter and also survival enhancer. The aim of this study was to investigate effect on mortality using both ambient individual data. A 10-year cohort carried out primary cutaneous cases (n=972). Residential data were coupled with levels ultraviolet radiation (UV) provide measure exposure. Demographic, histological clinical obtained for all...
(1) Background: Interest in gender disparities epidemiology, clinical features, prognosis and health care chronic kidney disease patients is increasing. Aims of the study were to evaluate association between vascular access (arteriovenous fistula (AVF) or central venous catheter (CVC)) used at start hemodialysis (HD) investigate 1-year mortality. (2) Methods: The includes 9068 adult HD (64.7% males) registered Lazio Regional Dialysis Register (January 2008-December 2018). Multivariable...
ISEE-0548 Background and Objectives: Low temperatures have been associated with increases in mortality showing a geographical variability. The objective of this study was to estimate the impact low on cardiovascular, cerebrovascular respiratory hospital admissions, during cold period (October-March) twelve European cities included PHEWE project. Methods: For each city, time series analysis used model relationship between minimum temperature (lag 0–15 days) daily admissions by cause age group...