Yoonhee Kim

ORCID: 0000-0003-2517-1087
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About
Contact & Profiles
Research Areas
  • Climate Change and Health Impacts
  • Air Quality and Health Impacts
  • Global Health Care Issues
  • Health disparities and outcomes
  • Thermoregulation and physiological responses
  • Genetics and Neurodevelopmental Disorders
  • Genetic Associations and Epidemiology
  • Economic and Environmental Valuation
  • Thermal Regulation in Medicine
  • Malaria Research and Control
  • Psychosocial Factors Impacting Youth
  • Mosquito-borne diseases and control
  • Diverse Approaches in Healthcare and Education Studies
  • Education and Learning Interventions
  • Air Quality Monitoring and Forecasting
  • Water resources management and optimization
  • Suicide and Self-Harm Studies
  • Genetic and phenotypic traits in livestock
  • Health, Environment, Cognitive Aging
  • Diverse Topics in Contemporary Research
  • RNA Research and Splicing
  • Korean Urban and Social Studies
  • Education, Safety, and Science Studies
  • Child Nutrition and Water Access
  • Educational Systems and Policies

The University of Tokyo
2018-2025

Ewha Womans University
2024-2025

Korea University
2017-2024

Yonsei University
2008-2024

Yonsei University College of Dentistry
2024

Monash University
2024

Ludwig-Maximilians-Universität München
2024

National Institute for Environmental Studies
2024

Universidad Pablo de Olavide
2024

Seoul National University Bundang Hospital
2023-2024

Abstract Epidemiological analyses of health risks associated with non-optimal temperature are traditionally based on ground observations from weather stations that offer limited spatial and temporal coverage. Climate reanalysis represents an alternative option provide complete spatio-temporal exposure coverage, yet to be systematically explored for their suitability in assessing temperature-related at a global scale. Here we the first comprehensive analysis over multiple regions assess most...

10.1038/s41598-022-09049-4 article EN cc-by Scientific Reports 2022-03-25

The case-crossover design is widely used in environmental epidemiology as an effective alternative to the conventional time-series regression estimate short-term associations of exposures with a range acute events. This tutorial illustrates implementation time-stratified study aggregated health outcomes and exposures, such particulate matter air pollution, focusing on adjusting covariates investigating effect modification using conditional Poisson regression. Time-varying confounders can be...

10.1093/ije/dyae020 article EN cc-by-nc-nd International Journal of Epidemiology 2024-02-14

Using purified proteins from calf and a synthetic substrate, we have reconstituted the enzymatic reactions required for mammalian Okazaki fragment processing in vitro. The are removal of initiator RNA, synthesis an upstream to generate nick, then ligation. With our RNase H type I (RNase HI) makes single cut one nucleotide 5' RNA-DNA junction. double strand specific 3' exonuclease removes remaining monoribonucleotide. After dissociation cleaved by DNA polymerase generates which is sealed...

10.1073/pnas.91.21.9803 article EN Proceedings of the National Academy of Sciences 1994-10-11

Air pollution is known to contribute respiratory and cardiovascular mortality morbidity. Oxidative stress has been suggested as one of the main mechanisms for these effects on health.The aim this study was analyze exposure particulate matter (PM) with aerodynamic diameters < or = 10 microm (PM10) 2.5 (PM2.5) polycyclic aromatic hydrocarbons (PAHs) urinary malondialdehyde (MDA) levels in schoolchildren.The population consisted 120 schoolchildren. The survey measurements were conducted four...

10.1289/ehp.0901077 article EN public-domain Environmental Health Perspectives 2009-12-14

Genome-wide association studies (GWAS) are a powerful means of identifying genes with disease-associated common variants, but they not well-suited to detecting rare and low-frequency variants. In the current study Behçet disease (BD), nonsynonymous variants (NSVs) identified by deep exonic resequencing 10 found GWAS ( IL10, IL23R , CCR1 STAT4 KLRK1 KLRC1, KLRC2, KLRC3, KLRC4 ERAP1 ) 11 selected for their role in innate immunity (IL1B, IL1R1, IL1RN, NLRP3, MEFV, TNFRSF1A, PSTPIP1, CASP1,...

10.1073/pnas.1306352110 article EN Proceedings of the National Academy of Sciences 2013-04-30

Volatile organic compounds (VOCs) are reported to cause adverse effects on pulmonary function in occupationally exposed workers. However, evidence is lacking the effect general population. We hypothesised that VOCs impair through enhancing oxidative stress, especially elderly A longitudinal panel study of 154 people was performed South Korea. Repeated spirometric tests were up eight times different days for each subject. also measured urinary concentrations metabolites VOC and markers stress...

10.1183/09031936.00153509 article EN European Respiratory Journal 2010-03-29

BackgroundA limited number of studies suggest that ambient temperature contributes to suicide; these typically focus on a single nation and use temporally spatially aggregated data.ObjectiveWe evaluated the association between suicide in multiple cities three East Asian countries.MethodsA time-stratified case-crossover method was used explore relationship suicide, adjusting for potential time-varying confounders time-invariant individual characteristics. Sex- age-specific associations with...

10.1289/ehp.1409392 article EN public-domain Environmental Health Perspectives 2015-06-12

Various retrospective studies have reported on the increase of mortality risk due to higher diurnal temperature range (DTR). This study projects effect DTR future across 445 communities in 20 countries and regions.DTR-related was estimated basis historical daily time-series weather factors from Jan 1, 1985, Dec 31, 2015, with data for regions, Multi-Country Multi-City Collaborative Research Network. We obtained projected series associated four climate change scenarios, using representative...

10.1016/s2542-5196(20)30222-9 article EN cc-by-nc-nd The Lancet Planetary Health 2020-11-01

Minimum mortality temperature (MMT) is an important indicator to assess the temperature-mortality association, indicating long-term adaptation local climate. Limited evidence about geographical variability of MMT available at a global scale.We collected data from 658 communities in 43 countries under different climates. We estimated associations derive for each community using Poisson regression with distributed lag nonlinear models. investigated variation by climatic zone mixed-effects...

10.1097/ee9.0000000000000169 article EN cc-by-nc-nd Environmental Epidemiology 2021-09-24

BackgroundClimate change can directly impact temperature-related excess deaths and might subsequently the seasonal variation in mortality. In this study, we aimed to provide a systematic comprehensive assessment of potential future changes variation, or seasonality, mortality across different climate zones.MethodsIn modelling collected daily time series mean temperature (all causes non-external only) via Multi-Country Multi-City Collaborative (MCC) Research Network. These data were during...

10.1016/s2542-5196(23)00269-3 article EN cc-by-nc-nd The Lancet Planetary Health 2024-02-01
Yuan Gao Wenzhong Huang Qi Zhao Niilo Ryti Ben Armstrong and 91 more Antonio Gasparrini Shilu Tong Mathilde Pascal Aleš Urban Ariana Zeka Éric Lavigne Joana Madureira Patrick Goodman Veronika Huber Bertil Forsberg Jan Kyselý Francesco Sera Yuming Guo Shanshan Li Yuan Gao Wenzhong Huang Qi Zhao Niilo Ryti Ben Armstrong Antonio Gasparrini Shilu Tong Mathilde Pascal Aleš Urban Ariana Zeka Éric Lavigne Joana Madureira Patrick Goodman Veronika Huber Bertil Forsberg Jan Kyselý Francesco Sera Michelle L. Bell Simon Hales Yasushi Honda Jouni J. K. Jaakkola Aurelio Tobı́as Ana María Vicedo-Cabrera Rosana Abrutzky Micheline de Sousa Zanotti Stagliorio Coêlho Paulo Hilário Nascimento Saldiva Patricia Matus Correa Nicolás Valdés Ortega Haidong Kan Samuel Osorio Dominic Royé Hans Orru Ene Indermitte Alexandra Schneider Klea Katsouyanni Antonis Analitis Hanne Krage Carlsen Fatemeh Mayvaneh Hematollah Roradeh Raanan Raz Paola Michelozzi Francesca deʼDonato Masahiro Hashizume Yoonhee Kim Barrak Alahmad John Paul Cauchy Magali Hurtado‐Díaz Eunice Elizabeth Félix Arellano César De la Cruz Valencia Ala Overcenco Danny Houthuijs Caroline Ameling Shilpa Rao Gabriel Carrasco-Escobar Xerxes Seposo Paul Lester Chua Susana das Neves Pereira da Silva Baltazar Nunes Iulian‐Horia Holobâcă Ivana Cvijanović Malcolm Mistry Noah Scovronick Fiorella Acquaotta Ho Kim Whanhee Lee Carmen Íñiguez Christofer Åström Shanshan Li Yue Leon Guo Shih‐Chun Pan Valentina Colistro Antonella Zanobetti Joel Schwartz Trần Ngọc Đăng Do Van Dung Yuming Guo Shanshan Li

BackgroundExposure to cold spells is associated with mortality. However, little known about the global mortality burden of spells.MethodsA three-stage meta-analytical method was used estimate by means a time series dataset 1960 locations across 59 countries (or regions). First, we fitted location-specific, spell-related associations using quasi-Poisson regression distributed lag non-linear model period up 21 days. Second, built multivariate meta-regression between location-specific and seven...

10.1016/s2542-5196(23)00277-2 article EN cc-by-nc-nd The Lancet Planetary Health 2024-02-01

BackgroundDespite extensive findings on the hazardous impacts of environmental heat exposure, little is known about effect people with disabilities. This study aimed to estimate association between exposure and emergency department admissions for disabilities compared without disabilities.MethodsIn this nationwide, case-crossover study, we linked data (cases) any cause in warm season South Korea from Korean National Health Insurance Service (NHIS)–National Sample Cohort database (a...

10.1016/s2542-5196(24)00027-5 article EN cc-by The Lancet Planetary Health 2024-04-01

Cambodia is prone to extreme weather events, especially floods, droughts and typhoons. Climate change predicted increase the frequency intensity of such events. The Cambodian population highly vulnerable impacts these events due poverty; malnutrition; agricultural dependence; settlements in flood-prone areas, public health, governance technological limitations. Yet little known about health Cambodia. Given extremely low adaptive capacity population, this a crucial knowledge gap. A literature...

10.3390/ijerph120100191 article EN International Journal of Environmental Research and Public Health 2014-12-23
Themistocles L. Assimes Hilma Hólm Sekar Kathiresan Muredach P. Reilly Guðmar Þorleifsson and 95 more Benjamin F. Voight Jeanette Erdmann Christina Willenborg Dhananjay Vaidya Changchun Xie C. C. Patterson Thomas M. Morgan Mary Susan Burnett Mingyao Li Mark A. Hlatky Joshua W. Knowles John R. Thompson Devin Absher Carlos Iribarren Alan S. Go Stephen P. Fortmann Stephen Sidney Neil Risch Hua Tang Richard M. Myers Kenneth I. Berger Monika Stoll Svati H. Shah Guðmundur Þorgeirsson Karl Andersen Aki S. Havulinna J. Enrique Herrera Nauder Faraday Yoonhee Kim Brian G. Kral Rasika A. Mathias Ingo Ruczinski Bhoom Suktitipat Alexander F. Wilson Lisa R. Yanek Lewis C. Becker Patrick Linsel‐Nitschke Wolfgang Lieb Inke R. König Christian Hengstenberg Marcus Fischer Klaus Stark Wibke Reinhard Janina Winogradow Martina Grassl Anika Großhennig Michael Preuß Stefan Schreiber H-Erich Wichmann Christa Meisinger Jean Yee Yechiel Friedlander Ron Do James B. Meigs Gordon H. Williams David M. Nathan Calum A. MacRae Liming Qu Robert L. Wilensky William Matthai Atif Qasim Håkon Håkonarson Augusto D. Pichard Kenneth M. Kent Lowell F. Satler Joseph Lindsay Ron Waksman Christopher W. Knouff Dawn Waterworth Max Walker Vincent Mooser Jaume Marrugat Gavin Lucas Isaac Subirana Joan Sala Rafel Ramos Nicola Martinelli Oliviero Olivieri Elisabetta Trabetti Giovanni Malerba Pier Franco Pignatti Candace Guiducci Daniel B. Mirel Melissa Parkin Joel N. Hirschhorn Rosanna Asselta Stefano Duga Yan V. Sun Mark J. Daly Shaun Purcell Sandra Eifert Peter S. Braund Benjamin J. Wright Anthony J. Balmforth Stephen G. Ball

10.1016/j.jacc.2010.06.022 article EN publisher-specific-oa Journal of the American College of Cardiology 2010-10-08

Previous studies have shown that population susceptibility to non-optimum temperatures has changed over time, but little is known about the related time-varying factors underlie changes.Our objective was investigate changing in 47 prefectures of Japan four decades from 1972 2012, addressing three aspects: minimum mortality temperature (MMT) and heat- cold-related risks. In addition, we aimed examine how these aspects were associated with climate, demographic, socioeconomic variables.We first...

10.1289/ehp2546 article EN public-domain Environmental Health Perspectives 2018-05-04

Background: There is growing evidence suggesting an association between air pollution and suicide. However, previous findings varied depending on the type of pollutant study location. Objectives: We examined pollutants suicide in 10 large cities South Korea, Japan, Taiwan. Methods: used a two-stage meta-analysis. First, we conducted time-stratified case-crossover analysis to estimate short-term nitrogen dioxide (NO2), sulfur (SO2), particulate matter [aerodynamic diameter ≤10μm (PM10),...

10.1289/ehp2223 article EN public-domain Environmental Health Perspectives 2018-03-12
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