- Inflammatory Bowel Disease
- Microscopic Colitis
- Autoimmune and Inflammatory Disorders
- Pneumonia and Respiratory Infections
- Diverticular Disease and Complications
- Bacterial Infections and Vaccines
- Diagnosis and treatment of tuberculosis
- Appendicitis Diagnosis and Management
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Urinary Tract Infections Management
- Pancreatitis Pathology and Treatment
- Emergency and Acute Care Studies
- Intraperitoneal and Appendiceal Malignancies
- Nosocomial Infections in ICU
- Biliary and Gastrointestinal Fistulas
- Abdominal Surgery and Complications
- Genetic factors in colorectal cancer
- Meningioma and schwannoma management
- Colorectal Cancer Surgical Treatments
- Neurofibromatosis and Schwannoma Cases
- Geriatric Care and Nursing Homes
- Antibiotic Use and Resistance
- Ovarian cancer diagnosis and treatment
- Kawasaki Disease and Coronary Complications
Agenzia Regionale per la Protezione dell'ambiente ligure
2015-2024
Regione Liguria
2018-2023
Regione del Veneto
2018
University of Genoa
1999-2012
Ospedale Policlinico San Martino
2012
Candida auris is an emerging fungus that represents a serious health threat globally. In Italy, the first case was detected in July 2019. Then, one reported to Ministry of Health (MoH) on January 2020. Nine months later, huge number cases were northern Italy. Overall, 361 17 healthcare facilities between 2019 and December 2022 Liguria, Piedmont, Emilia-Romagna, Veneto regions, including 146 (40.4%) deaths. The majority (91.8%) considered as colonised. Only had history travel abroad....
Carcinoids of the appendix continue to be interest, despite their low incidence. There is still considerable controversy surrounding these tumors, especially with regard role right hemicolectomy in surgical management. The aim this work was explicate current therapeutic knowledge and review criteria for indications appendectomy or hemicolectomy.The records patients who underwent appendectomies from 1990 2000 were analyzed. Seven included study. clinical data reviewed demographic details,...
Protein recombinant vaccine NVX-CoV2373 (Novavax) against COVID-19 was authorized for its use in adults late 2021, but evidence on estimated effectiveness a general population is lacking.To estimate of primary cycle with SARS-CoV-2 infection and symptomatic COVID-19.Retrospective cohort study linking data from the national vaccination registry surveillance system Italy during period Omicron predominance. All starting between February 28 September 4, 2022, were included, follow-up ending 25,...
The SARS-CoV-2 pandemic continues to spread worldwide, generating a high impact on healthcare systems. aim of the study was examine epidemiological burden reinfections and identify potential related risk factors. A retrospective observational conducted in Liguria Region, combining data from National Vaccines Registry Regional Chronic Condition Data Warehouse. In period (September 2021 May 2022), 335,117 cases infection were recorded Liguria, which 15,715 reinfected once. During Omicron phase...
Vaccines are a fundamental weapon against number of infections that may cause severe disease or sequelae, both in the absence presence etiologic therapy, have high socio-economic impact terms hospital admissions requests for medical examination. COVID-19, serious infection due to SARS-CoV-2, exemplifies all these characteristics. In Italy, paediatric SARS-CoV-2 presented most cases with few symptoms even asymptomatic form, although nearly 20% children enrolled nationwide registry developed...
Importance Population-based data on the 4-component recombinant protein–based (4CMenB) vaccine effectiveness and reduction in incidence rate ratios (IRRs) are continuously needed to assess performance prevention of serogroup B invasive meningococcal disease (IMD). Objective To IRRs associated with 4CMenB pediatric population 6 regions Italy. Design, Setting, Participants This retrospective cohort screening study case-control included from children aged younger than years highly populated...
Vaccinations against Streptococcus pneumoniae are included in infant immunization programs globally. However, a substantial burden due to pneumococcal disease (PD) remains. This study aimed estimate the cost of emergency department (ED) visits and hospitalizations associated with invasive disease, all-cause pneumonia, acute otitis media children <15 years age Liguria region Italy between 2012 2018. The retrospective cohort used data from Region Administrative Health Databases Ligurian...
The Italian National Action Plan to contrast AMR identified among its objectives the development and implementation of a national Healthcare-Associated Infection (HAI) surveillance system based on European Centre for Disease Prevention Control (ECDC) indications, through point prevalence surveys (PPS) HAIs antibiotic use in acute-care hospitals long-term care facilities (LTCFs). We aimed assess feasibility appropriateness proposed tools LTCFs.Point survey.A pilot PPS was conducted between...
According to WHO estimates, varicella disease is responsible of a worldwide significant burden in terms hospitalizations, complications, and deaths, with more than 90% cases under 12 years old. This study aims at evaluating the clinical, epidemiological, economic Ligurian children, about comorbidities, organizational variables, vaccination coverages from 2010 2017, Emergency Department accesses hospitalizations. The overall hospitalization rate was 179.76 (per 100,000 inhab.), gradual but...
Perianal fistula is a very debilitating event and cause of morbidity in patients with Crohn's disease (CD). Its malignant transformation rare an incidence around 0.004-0.7$. Presence the colon rectum major risk factor for development perianal fistula. In this report we show case adenocarcinoma arising from fistulizing CD. This type tumor highly aggressive, difficult to diagnose, has rather poor prognosis. The different neoplastic transformations types tumors that may appear CD, especially at...
Despite the availability of vaccines against Streptococcus pneumoniae, global incidence and economic cost pneumococcal disease (PD) among adults is still high. This retrospective cohort analysis estimated emergency department (ED) visits/hospitalizations associated with non-invasive pneumonia invasive individuals ≥15 years age in Liguria region Italy during 2012-2018. Data from Region Administrative Health Databases Ligurian Chronic Condition Warehouse were used, including hospital admission...
As known, influenza presents a multifaceted challenge to public health, causing disease that ranges from mild cases severe pandemics with significant morbidity and mortality. Effective pandemic preparedness demands comprehensive strategy integrates research, surveillance, response coordination community engagement, mitigate the impact of future health emergencies. The cycle involves dynamic, cyclical phases preparation aimed at enhancing capacity. Italy's 2021-2023 National...
This retrospective analysis aims to follow the course of SARS-CoV-2 infections in pediatric population residing Liguria, North-west Italy, from March 2020 December 2022 and relate it regional national containment measures adopted, assess representativeness infection rate observed at level analyze vaccination rates different groups. First episodes registered surveillance system were extracted further anonymously analyzed for subjects aging ≤ 19 years. The absolute number cases diagnosed daily...