A5035268766- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Aortic Disease and Treatment Approaches
- Transplantation: Methods and Outcomes
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Ischemia and Reperfusion
- Cardiac Arrest and Resuscitation
- Cardiac pacing and defibrillation studies
- Organ Transplantation Techniques and Outcomes
- Heart Failure Treatment and Management
- Cardiac Arrhythmias and Treatments
- Aortic aneurysm repair treatments
- Congenital Heart Disease Studies
- Atrial Fibrillation Management and Outcomes
- Antiplatelet Therapy and Cardiovascular Diseases
- Coronary Interventions and Diagnostics
- Cardiovascular Function and Risk Factors
- Cardiac Imaging and Diagnostics
- Peptidase Inhibition and Analysis
- Renal Transplantation Outcomes and Treatments
- Trauma Management and Diagnosis
- Ubiquitin and proteasome pathways
Klinikum Links der Weser
2021-2025
Leipzig Heart Institute
2014-2023
Heinrich Heine University Düsseldorf
2023
Hôpital Louis Pradel
2023
University of Rostock
2023
Deutsches Herzzentrum der Charité
2009-2021
Leipzig University
2011-2021
University Hospital Leipzig
2018-2021
Leipzig/Halle Airport
2021
Friedrich Schiller University Jena
2021
Background: Cardiac surgery often represents the only treatment option in patients with infective endocarditis (IE). However, IE may lead to a sudden release of inflammatory mediators, which is associated postoperative organ dysfunction. We investigated effect hemoadsorption during on Methods: This multicenter, randomized, nonblinded, controlled trial assigned undergoing cardiac for (integration CytoSorb cardiopulmonary bypass) or control. The primary outcome (change sequential failure...
Objectives To assess the clinical sensitivity of causes death, concomitant diseases and postoperative complications including thromboembolic events in ECMO patients. Methods: Between January 2000 December 2004 154/202 patients (76.2%) died after postcardiotomy circulatory support. Autopsy was performed 78 (50.6%) consecutive Clinical post-mortem data were prospectively recorded compared concerning death venous arterial thromboembolisms significant comorbidities. Results Mean age 62.1±11.3...
To compare early and long-term outcomes of minimally invasive surgery (MIS) versus full sternotomy (FS) isolated aortic valve replacement (AVR).We retrospectively analysed all patients who underwent bioprosthetic AVR between 2003 March 2012 at our institution. Matching was performed based on a propensity score, which obtained using the output logistic regression relevant preoperative risk factors. Mean follow-up 3.1±2.7 years (range 0-9.0 years) 99.8% complete.A total 2051 (FS, 1572; MIS,...
Background Extracorporeal membrane oxygenation (ECMO) has been increasingly used for postcardiotomy cardiogenic shock, but without a concomitant reduction in observed in-hospital mortality. Long-term outcomes are unknown. This study describes patients' characteristics, outcome, and 10-year survival after ECMO. Variables associated with postdischarge mortality investigated reported. Methods Results The retrospective international multicenter observational PELS-1 (Postcardiotomy Life Support)...
Background— The objective was to evaluate the impact of complete revascularization (CR) versus reasonable incomplete surgical (IR) in others than left anterior descending artery territory on early and late survival patients with multivessel coronary disease (CAD). Methods Results— During a 7-year period, 8.806 consecutive CAD affecting proximal or main stem underwent sternotomy for isolated bypass grafting including internal mammary artery-left bypass. A total 936 (10.6%) had IR circumflex...
Iatrogenic aortic dissection (IAD) is a rare complication of cardiac procedures. We herein describe our management and results this complication. A total 55 279 patients underwent open heart surgery at centre from 1995 to 2010, 135 262 catheterization over the same time period. identified 48 cohort who emergency for IAD that occurred either during or shortly after surgery, following catheterization. The incidence was 0.06% (n = 36) surgical procedures 0.01% 12) mean patient age 66 ± 14 years...
ObjectivesPostcardiotomy extracorporeal membrane oxygenation (ECMO) can be initiated intraoperatively or postoperatively based on indications, settings, patient profile, and conditions. The topic of implantation timing only recently gained attention from the clinical community. We compare characteristics as well in-hospital long-term survival between intraoperative postoperative ECMO.MethodsThe retrospective, multicenter, observational Postcardiotomy Extracorporeal Life Support (PELS-1)...
Objective: Cardiopulmonary bypass (CPB) support is required in some lung transplantation (LTX) operations. CPB and full-dose heparin increases the risks of bleeding early graft dysfunction. We report our experiences replacing with heparin-bonded low-dose extracorporeal membrane oxygenation (ECMO) LTX surgery. Methods: From 2003 to 2005 forty-seven patients were transplanted. Thirty-seven retrospectively evaluated for this study (10 excluded due heart-lung-, lung-kidney transplantation,...
The study objective was to evaluate the outcomes of surgery for active infective endocarditis with aortic root abscess formation.Between July 1996 and June 2009, 1161 patients underwent operation valve endocarditis, whom 172 had abscess. infected native in 96 prosthetic 76 patients. Patients' mean age (± standard deviation) logistic EuroSCORE-predicted risk mortality were 62 ± 13 years 23.1% 26%, respectively. Surgery emergent (58%). involved annulus 90 (52%), intervalvular fibrous body 81...
The David aortic valve-sparing reimplantation (AVr-D) operation is increasingly being used in patients with root aneurysmal disease and pliable cusps. objective of this study was to assess our early medium-term outcomes the AVr-D operation.Between 2003 2011, a total 179 underwent procedures. mean patient age 49.7 ± 15.1 years, 23.5% (n = 42) were females. Marfan syndrome present 17.3% 31), acute Type A dissection 15.6% 28). Clinical follow-up 100% complete 1.8 1.6 years (0 days 7.5 years)...
Background Iatrogenic coronary artery injuries during percutaneous interventions ( PCI ) often require emergent surgical management. Our study evaluated the early and long‐term outcomes in patients undergoing treatment of iatrogenic complications identified predictors operative mortality. Methods Results Pre‐, intra‐ post‐operative data hospital 168 consecutive cardiac procedures for following between December 1999 July 2015, were prospectively collected our computerized database. Logistic...
Abstract Background Significant bleeding is a well known complication after cardiac surgical procedures and associated with worse outcome. Thrombelastometry (ROTEM®) allows point-of-care testing of the coagulation status but only limited data available yet. The aim was to evaluate ROTEM®-guided blood component therapy in randomized trial. Methods In case significant postoperative (> 200 ml/h) following elective isolated or combined (including 14% re-do 4% requiring circulatory arrest)...