A5009073133- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Cardiac Structural Anomalies and Repair
- Intensive Care Unit Cognitive Disorders
- Blood transfusion and management
- Transplantation: Methods and Outcomes
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac and Coronary Surgery Techniques
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- COVID-19 Clinical Research Studies
- Heart Failure Treatment and Management
- Cardiac Valve Diseases and Treatments
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Aortic Disease and Treatment Approaches
- Organ Transplantation Techniques and Outcomes
- Advanced MRI Techniques and Applications
- Renal Transplantation Outcomes and Treatments
- Acute Kidney Injury Research
- Cardiac Ischemia and Reperfusion
- Surgical site infection prevention
- Airway Management and Intubation Techniques
- COVID-19 and healthcare impacts
Johns Hopkins University
2016-2025
Johns Hopkins Medicine
2016-2025
Johns Hopkins Hospital
2014-2025
Thomas Jefferson University
2009-2024
Brown University
2023-2024
University of Pennsylvania
2023-2024
John Brown University
2023-2024
Our Lady of Lourdes Medical Center
2024
San Diego Cardiac Center
2024
University of Virginia
2023
Some observational studies have reported that transfusion of red-cell units been stored for more than 2 to 3 weeks is associated with serious, even fatal, adverse events. Patients undergoing cardiac surgery may be especially vulnerable the effects transfusion.We conducted a randomized trial at multiple sites from 2010 2014. Participants 12 years age or older who were complex and likely undergo red cells randomly assigned receive leukocyte-reduced 10 days less (shorter-term storage group) 21...
In the setting of current novel coronavirus pandemic, this document has been generated to provide guiding statements for adult cardiac surgeon consider in a rapidly evolving national landscape. Acknowledging risk potentially prolonged need surgery procedure deferral, we have created proposed template physicians and interdisciplinary teams protecting their patients, institution, highly specialized team. addition, recommendations on transition from traditional in-person patient assessments...
Optimal neurologic monitoring methods have not been characterized for patients on extracorporeal membrane oxygenation (ECMO). We assessed the feasibility of noninvasive multimodal neuromonitoring (NMN) to prognosticate outcome. In this prospective observational study, examinations, transcranial Doppler (TCD), electroencephalography (EEG), and somatosensory evoked potentials (SSEPs) were performed at prespecified intervals. Outcome discharge was defined as favorable when modified Rankin Scale...
Objectives: Although acute brain injury is common in patients receiving extracorporeal membrane oxygenation, little known regarding the mechanism and predictors of ischemic hemorrhagic stroke. We aimed to determine risk factors outcomes each stroke with venoarterial oxygenation support. Design: Retrospective analysis. Setting: Data reported Extracorporeal Life Support Organization by 310 centers from 2013 2017. Patients: Patients more than 18 years old supported a single run oxygenation....
Abstract Background To assess the safety and feasibility of imaging brain with a point-of-care (POC) magnetic resonance (MRI) system in patients on extracorporeal membrane oxygenation (ECMO). Early detection acute injury (ABI) is critical improving survival for ECMO support. Methods Patients from single tertiary academic center who underwent head CT (HCT), followed by POC MRI examinations within 24 h following HCT while ECMO. Primary outcomes were feasibility, defined as completion...
Abstract Background While venoarterial extracorporeal membrane oxygenation (V-A ECMO) provides lifesaving support for cardiopulmonary failure, complications may increase mortality, with few studies focusing on ischemic/hemorrhagic stroke. We aimed to determine the trends and associations of stroke incidence their risk factors, including effects annual case volumes ECMO centers. Methods Retrospective analysis was performed Extracorporeal Life Support Organization (ELSO) registry, adult V-A...
ABGarterial blood gas ABI acute brain injury AUC-ROC Conclusions:In the largest study predicting neurological complications with ML in ECMO, longer ECMO duration and higher 24h pump flow were associated non-ECPR ECPR VA-ECMO.
Abstract Although it is known that coronavirus disease 2019 can present with a range of neurological manifestations and in-hospital complications, sparse data exist on whether these initial symptoms are closely associated post-acute sequelae SARS-CoV-2 (severe acute respiratory syndrome 2; PANSC) female versus male sex impacts symptom resolution. In this international, multi-centre, prospective, observational study across 407 sites from 15 countries (30 January 2020 to 30 April 2022), we...
OBJECTIVES: Stroke is commonly reported in patients receiving venovenous extracorporeal membrane oxygenation, but risk factors are not well described. We sought to determine preextracorporeal oxygenation and on-extracorporeal for both ischemic hemorrhagic strokes with support. DESIGN: Retrospective analysis. SETTING: Data the Extracorporeal Life Support Organization by 366 centers from 2013 2019. PATIENTS: Patients older than 18 years supported a single run of oxygenation. INTERVENTIONS:...
Objectives: Current studies lack information on characteristics of acute brain injury in patients with extracorporeal membrane oxygenation. We sought to characterize the types, timing, and risk factors Design: Retrospective analysis. Setting: reviewed oxygenation who had undergone autopsy gross microscopic examinations from January 2009 December 2018 a single tertiary center. Patients: Twenty-five (median age 53 yr) postmortem autopsy. Interventions: Description analysis neuropathologic...