Joaquín Baruch
A5071128639- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and healthcare impacts
- COVID-19 and Mental Health
- Vaccine Coverage and Hesitancy
- Animal Disease Management and Epidemiology
- Viral Infections and Outbreaks Research
- Intensive Care Unit Cognitive Disorders
- COVID-19 diagnosis using AI
- Microbial infections and disease research
- SARS-CoV-2 detection and testing
- Machine Learning in Healthcare
- Listeria monocytogenes in Food Safety
- Sepsis Diagnosis and Treatment
- Pancreatitis Pathology and Treatment
- Vector-Borne Animal Diseases
- Immune responses and vaccinations
- Respiratory Support and Mechanisms
- COVID-19 epidemiological studies
- Data-Driven Disease Surveillance
- Healthcare Systems and Public Health
- Gout, Hyperuricemia, Uric Acid
- Bacillus and Francisella bacterial research
- Brucella: diagnosis, epidemiology, treatment
Kansas State University
2018-2024
University of Oxford
2020-2024
Johns Hopkins Hospital
2024
European Centre for Disease Prevention and Control
2022-2024
All India Institute of Medical Sciences Rishikesh
2023
Robert Koch Institute
2023
Ministry for Health
2022-2023
All India Institute of Medical Sciences Raipur
2023
Oxford Centre for Mission Studies
2022
Angkor Hospital for Children
2021
Abstract Background We describe demographic features, treatments and clinical outcomes in the International Severe Acute Respiratory emerging Infection Consortium (ISARIC) COVID-19 cohort, one of world's largest international, standardized data sets concerning hospitalized patients. Methods The set analysed includes patients between January 2020 2022 52 countries. investigated how symptoms on admission, co-morbidities, risk factors varied by age, sex other characteristics. used Cox...
Abstract Although it is known that coronavirus disease 2019 can present with a range of neurological manifestations and in-hospital complications, sparse data exist on whether these initial symptoms are closely associated post-acute sequelae SARS-CoV-2 (severe acute respiratory syndrome 2; PANSC) female versus male sex impacts symptom resolution. In this international, multi-centre, prospective, observational study across 407 sites from 15 countries (30 January 2020 to 30 April 2022), we...
Abstract ISARIC (International Severe Acute Respiratory and emerging Infections Consortium) partnerships outbreak preparedness initiatives enabled the rapid launch of standardised clinical data collection on COVID-19 in Jan 2020. Extensive global participation has resulted a large, comprehensive from hundreds sites across dozens countries. Data are analysed regularly reported publicly to inform patient care public health response. This report, our 18th final is part series published over 3...
Introduction The I-MOVE-COVID-19 and VEBIS hospital networks have been measuring COVID-19 vaccine effectiveness (VE) in participating European countries since early 2021. Aim We aimed to measure VE against PCR-confirmed SARS-CoV-2 patients ≥ 20 years hospitalised with severe acute respiratory infection (SARI) from December 2021 July 2022 (Omicron-dominant period). Methods In both networks, 46 hospitals (13 countries) follow a similar test-negative case–control protocol. defined complete...
Abstract The objective of this study was to evaluate the diagnostic performance chute-side methods for detecting physiological and pathological changes as indicators early bovine respiratory disease (BRD) in calves experimentally inoculated with infectious rhinotracheitis virus (IBR) Mannheimia haemolytica (Mh). A challenge performed over 14 d 30 Holstein steers [average weight (±SEM) = 211 kilograms (kg) ± 2.4 kg] on day 0 IBR 6 Mh. Diagnostic included clinical illness scores (CIS), lung...
Whilst timely clinical characterisation of infections caused by novel SARS-CoV-2 variants is necessary for evidence-based policy response, individual-level data on infecting are typically only available a minority patients and settings. Here, we propose an innovative approach to study changes in COVID-19 hospital presentation outcomes after the Omicron variant emergence using publicly population-level relative frequency infer likely responsible cases. We apply this method collected large...
There is potentially considerable variation in the nature and duration of care provided to hospitalised patients during an infectious disease epidemic or pandemic. Improvements clinician confidence may shorten time spent as inpatient, need for admission intensive unit (ICU) high dependency (HDU). On other hand, limited resources at times demand lead rationing. Nevertheless, these variables be used static proxies severity, outcome measures trials, inform planning logistics.
Abstract Introduction Case definitions are used to guide clinical practice, surveillance and research protocols. However, how they identify COVID‐19‐hospitalised patients is not fully understood. We analysed the proportion of hospitalised with laboratory‐confirmed COVID‐19, in ISARIC prospective cohort study database, meeting widely case definitions. Methods Patients were assessed using Centers for Disease Control (CDC), European Centre Prevention (ECDC), World Health Organization (WHO) UK...
Background Using a large dataset, we evaluated prevalence and severity of alterations in liver enzymes COVID-19 association with patient-centred outcomes. Methods We included hospitalized patients confirmed or suspected SARS-CoV-2 infection from the International Severe Acute Respiratory emerging Infection Consortium (ISARIC) database. Key exposure was baseline (AST, ALT, bilirubin). Patients were assigned Liver Injury Classification score based on 3 components at admission: Normal; Stage I)...
BackgroundIndividuals vaccinated against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), when infected, can still develop disease that requires hospitalization. It remains unclear whether these patients differ from hospitalized unvaccinated with regard to presentation, coexisting comorbidities, and outcomes.MethodsHere, we use data an international consortium study this question assess differences between groups are context specific. Data 83,163 COVID-19 (34,843 vaccinated,...
Introduction Two large multicentre European hospital networks have estimated vaccine effectiveness (VE) against COVID-19 since 2021. Aim We aimed to measure VE PCR-confirmed SARS-CoV-2 in hospitalised severe acute respiratory illness (SARI) patients ≥ 20 years, combining data from these during Alpha (March–June)- and Delta (June–December)-dominant periods, Methods Forty-six participating hospitals across 14 countries follow a similar generic protocol using the test-negative case–control...
By December 2021, administration of the third dose COVID-19 vaccinations coincided with spread Omicron variant in Europe. Questions had been raised on protection against infection conferred by previous vaccination and/or infection. Our study population included 252,433 participants from registry Malta. Data were then matched national testing database. We collected status, vaccine brand, date, history, and age. Using logistic regression, we examined different combinations dose, prior status...
Bovine brucellosis has been under eradication in Uruguay since 1998. The program includes, among other interventions, individual sera sampling of beef animals at slaughter, and annual serum testing all dairy cows-accounting for two million samples annually. At a herd prevalence 0.8%, pooled-sera sample approach could reduce the economic burden surveillance system by reducing operational costs. Our objective was to evaluate analytic sensitivity an indirect ELISA test Brucella abortus pools....
One Health disease-control programs are believed to be most effective when implemented within the population transmitting disease. The World Organization (WHO) and partners have targeted elimination of dog-mediated human rabies by 2030 primarily through mass dog vaccination. Mass vaccination, however, has been constrained financial resource limitations. current owner-charged vaccination strategy, used in resource-limited countries like Ethiopia, not reached minimum coverage required build...
In late 2020, the European Centre for Disease Prevention and Control Epiconcept started implementing a surveillance system severe acute respiratory infections (SARI) across Europe.We sought to describe process of digitizing upgrading SARI in Malta, an island country with centralized health system, during COVID-19 pandemic from February November 2021. We described characteristics people included compared different case definitions, including their advantages disadvantages. This study also...
On 14 February 2021, Lebanon implemented nationwide vaccination, offering the Pfizer-BioNTech (BNT162b2) vaccine to adults over 50 years of age. We estimated effectiveness in preventing symptomatic laboratory-confirmed COVID-19. conducted a test-negative case–control (TND) study among aged and older who presented with influenza-like illness (ILI) or COVID-19-like (CLI) surveillance sentinel sites between 1 July 31 December 2021. Unvaccinated participants did not receive any dose before...
Blood leukocyte differentials can be useful for understanding changes associated with bovine respiratory disease (BRD) progression. By improving turnaround time, point-of-care differential assays (PCLD) may provide logistical advantages to laboratory-based assays. Our objective was assess BRD progression in steers challenged herpesvirus 1 and Mannheimia haemolytica using blood differentials. Thirty Holstein (average body weight of 211 kg + 2.4 kg) were inoculated intranasally on day 0...
The study was conducted to determine the proportion and concentration of enterohemorrhagic
Our objectives were to determine whether the feedlot-level use of a direct-fed microbial (DFM; Lactobacillus animalis LA51 and Propionibacterium freudenreichii PF24; Bovamine Defend®, 2 × 10
Introduction: Case definitions are used to guide clinical practice, surveillance, and research protocols. However, how they identify COVID-19-hospitalised patients is not fully understood. We analysed the proportion of hospitalised with laboratory-confirmed COVID-19, in ISARIC prospective cohort study database, meeting widely case definitions. Methods: Patients were assessed using CDC, ECDC, WHO, UKHSA by age, region, time. fatality ratios (CFR) symptoms those who did meet evaluated....
This study objective was to evaluate the performance and applicability of multiple diagnostic tools measuring physiological, clinical, pathological changes as indicators early bovine respiratory disease (BRD) in calves experimentally inoculated with infectious rhinotracheitis virus (IBR) Mannheimia haemolytica (Mh).