A5027769052- Liver Disease Diagnosis and Treatment
- Ion channel regulation and function
- Dietary Effects on Health
- Cardiac electrophysiology and arrhythmias
- Prenatal Screening and Diagnostics
- Dermatological and COVID-19 studies
- Parvovirus B19 Infection Studies
- COVID-19 Clinical Research Studies
- Ion Transport and Channel Regulation
- Cancer Treatment and Pharmacology
- Natural Antidiabetic Agents Studies
- Magnesium in Health and Disease
- Diet and metabolism studies
- Neuroscience and Neuropharmacology Research
- Long-Term Effects of COVID-19
- Healthcare professionals’ stress and burnout
- Medication Adherence and Compliance
- Parathyroid Disorders and Treatments
- Pancreatitis Pathology and Treatment
- Engineering Diagnostics and Reliability
- HIV, Drug Use, Sexual Risk
- Fluid Dynamics and Mixing
- Aluminum toxicity and tolerance in plants and animals
- Medical Education and Admissions
- Cardiac Ischemia and Reperfusion
Ajman University
2021-2025
Al Ghurair University
2021
Milton Keynes Hospital
2021
University of Tübingen
2014-2016
Center for Vascular Biology Research
2016
University of Oslo
2003
Oslo University Hospital
2003
<b><i>Background/Aims: </i></b>Klotho, a protein mainly produced in the kidney and released into circulating blood, contributes to negative regulation of 1,25(OH)<sub>2</sub>D<sub>3</sub> formation is thus powerful regulator mineral metabolism. As β-glucuronidase, alpha Klotho further regulates stability several carriers channels plasma membrane channel transporter activity. Accordingly, participates diverse functions seemingly unrelated...
Abstract Background Medical students encounter various stressors during their studies. The study aimed to assess stress levels, sources, and associated determinants among Sudanese medical students. Method An online questionnaire-based was conducted 617 undergraduate of 6 different universities in Sudan. A 19-item questionnaire utilized addition demographics, manifestations, coping strategies. Results overall prevalence 31.7% ( p < 0.05). main sources were time pressure, heavy workload,...
Continuous therapeutic care with good medication adherence is the cornerstone of management all chronic diseases including diabetes. This study aimed to evaluate impact clinical pharmacist intervention on in individuals type 2 diabetes (T2DM). was a randomized, double-blind, controlled trial conducted at clinic located Omdurman Military Hospital, Sudan. Individuals T2DM attending within 1 year were selected. The sample size 364 participants (182 control and 182 interventional group). We used...
Cardiac remodelling associated with congestive heart failure typically involves dilatation of the ventricular cavities, cardiomyocyte hypertrophy and alterations extracellular matrix. Biglycan is an proteoglycan several recently appreciated functions including cell adhesion, collagen fibril assembly, growth factor interactions. The aims this study were to investigate regulation biglycan expression elucidate site(s) synthesis in myocardial tissue experimental model (HF).Myocardial samples...
<b><i>Background/Aims: </i></b>The WNK-dependent STE20/SPS1-related proline/alanine-rich kinase SPAK participates in the regulation of NaCl and Na<sup>+</sup>,K<sup>+</sup>,2Cl<sup>-</sup> cotransport thus renal salt excretion. The present study explored whether has similarly potential to regulate epithelial Na<sup>+</sup> channel (ENaC). <b><i>Methods: </i></b>ENaC was expressed...
A BSTRACT Diabetic ketoacidosis (DKA) is a life-threatening condition affecting individuals with diabetes characterised by hyperglycaemia, metabolic acidosis and ketonemia. The incidence financial burden of DKA still high. Thiamine deficiency well documented in patients could be associated cardiac dysfunction those patients. leads to dysfunction, neuronal death worsens the prognosis DKA. There an existing relationship between thiamine diabetes, obesity bariatric surgery. Careful monitoring...
Background: The serum & glucocorticoid inducible kinase isoform SGK3 is a powerful regulator of several transporters, ion channels and the Na+/K+ ATPase. Targets include ubiquitin ligase Nedd4-2, which in turn known voltage gated K+ channel Kv1.5 (KCNA5). present study thus explored whether modifies activity KCNA5, participates regulation diverse functions including atrial cardiac action potential, vascular smooth muscle cells, insulin release tumour cell proliferation. Methods: cRNA...
Background/Aims: Kir2.1 (KCNJ2) channels are expressed in neurons, skeletal muscle and cardiac tissue maintain the resting membrane potential. The activity of those is regulated by diverse signalling molecules. present study explored whether sensitive to transporter regulating kinases SPAK (SPS1-related proline/alanine-rich kinase) OSR1 (oxidative stress-responsive kinase 1), which turn WNK (with-no-K[Lys]) kinases. Methods: cRNA encoding was injected into Xenopus laevis oocytes with or...
The pleotropic functions of the large conductance Ca2+-activated K+ channels (maxi channel or BK channels) include regulation neuronal excitation and cell volume. Kinases participating in those glycogen synthase kinase GSK3 ß which is under negative control protein B (PKB/Akt). GSK3ß inhibited by antidepressant Lithium. present study thus explored whether modifies activity channels.cRNA encoding Ca2+ insensitive mutant BKM513I+Δ899-903 was injected into Xenopus laevis oocytes without with...
Mohamed H. Ahmed, Musaab Hassan Taha, Ahmed O. Almobarak, Wail Nuri Osman, Elhassan Abdullah, Azza Zulfu, Elmoubasher Farag, Abubaker Omer, Nazik E. Husain