A5046526166- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Clinical practice guidelines implementation
- COVID-19 and Mental Health
- SARS-CoV-2 and COVID-19 Research
- Intensive Care Unit Cognitive Disorders
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 and healthcare impacts
- Viral Infections and Outbreaks Research
- Disaster Response and Management
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Poxvirus research and outbreaks
- Viral Infections and Vectors
- Healthcare cost, quality, practices
- Health Policy Implementation Science
- Bacillus and Francisella bacterial research
- Primary Care and Health Outcomes
- Herpesvirus Infections and Treatments
- COVID-19 epidemiological studies
- Malaria Research and Control
- Mosquito-borne diseases and control
- Travel-related health issues
- Kawasaki Disease and Coronary Complications
- Machine Learning in Healthcare
University of Oxford
2020-2024
Johns Hopkins Hospital
2024
Oxford University Hospitals NHS Trust
2019-2023
University of Bristol
2023
Intensive Care National Audit & Research Centre
2021-2023
All India Institute of Medical Sciences Raipur
2023
All India Institute of Medical Sciences Rishikesh
2023
Oxford Research Group
2020-2022
Oxford Centre for Mission Studies
2022
Public Health Scotland
2021
Abstract Background We describe demographic features, treatments and clinical outcomes in the International Severe Acute Respiratory emerging Infection Consortium (ISARIC) COVID-19 cohort, one of world's largest international, standardized data sets concerning hospitalized patients. Methods The set analysed includes patients between January 2020 2022 52 countries. investigated how symptoms on admission, co-morbidities, risk factors varied by age, sex other characteristics. used Cox...
ABSTRACT Background While it is now apparent clinical sequelae (often called Long Covid) may persist after acute Covid-19, their nature, frequency, and aetiology are poorly characterised. This study aims to regularly synthesise evidence on Covid characteristics, inform management, rehabilitation, interventional studies improve long term outcomes. Methods A living systematic review. Medline, CINAHL (EBSCO), Global Health (Ovid), WHO Research Database LitCOVID, Google Scholar were searched up...
The challenges facing the evidence-based medicine (EBM) movement are well documented.1 2 Yet, problems early-career and mid-career researchers (EMCRs) working in ecosystem of EBM have not been articulated. coming together a cohort EMCRs from across globe enabled this articulation.3 2019 EBMLive conference (see box 1) provided space for to discuss problems, exchange ideas create list potential solutions. This article outlines four key faced by their solutions 2). Box 1 ### Conference The...
Acute intermittent porphyria (AIP) is an inherited deficiency in the haem biosynthesis pathway. AIP rare, affecting around 1 75 000 people. attacks are characterised by abdominal pain associated with autonomic, neurological and psychiatric symptoms. rarely posterior reversible encephalopathy syndrome (PRES). PRES a clinicoradiological condition caused failure of circulation to autoregulate, resulting cerebral oedema, headaches, nausea seizures. This association important because drugs used...
Abstract Direct‐MR neuronal detection (DND) of transient magnetic fields has recently been investigated as a novel imaging alternative to the conventional BOLD functional MRI (fMRI) technique. However, there remain controversial issues and debate surrounding this methodology, study attempts clarification by comparing responses in human visual system with those DND. relies on indirectly measuring blood oxygenation flow changes result activity, whereas putative DND method is based hypothesis...
There is potentially considerable variation in the nature and duration of care provided to hospitalised patients during an infectious disease epidemic or pandemic. Improvements clinician confidence may shorten time spent as inpatient, need for admission intensive unit (ICU) high dependency (HDU). On other hand, limited resources at times demand lead rationing. Nevertheless, these variables be used static proxies severity, outcome measures trials, inform planning logistics.
<h3>Objectives</h3> The rise of 'fake news' has achieved notoriety in the popular press over last few years. In scientific a similar problem, known as 'predator publishing' arisen. There is currently great debate about nature and extent publishing.' An informal consensus would suggest that junior academics are inundated by requests for articles from journals dubious quality. These same early career thought to be particularly vulnerable pressure 'publish or damned.' Relatively little data...
<ns3:p>Although the majority of people with Covid-19 will experience mild to moderate symptoms and recover fully, there is now increasing evidence that a significant proportion persistent for months after acute phase illness. These include, among others, fatigue, problems breathing, lack smell taste, headaches, depression anxiety. It also clear virus has lasting fluctuating multiorgan sequelae, including affecting not only respiratory system but heart, liver, nervous system.</ns3:p><ns3:p>...
<ns3:p><ns3:bold>Background</ns3:bold>: With a rapidly changing evidence base, high-quality clinical management guidelines (CMGs) are key tools for aiding decision making and increasing access to best available evidence-based care. A rapid review of COVID-19 CMGs found most lacked methodological rigour, overlooked at-risk populations, varied in treatment recommendations. Furthermore, social science literature highlights the complexity implementing local contexts where they were not developed...