A5101775076- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrest and Resuscitation
- Cardiac Ischemia and Reperfusion
- Acute Kidney Injury Research
- Cardiac and Coronary Surgery Techniques
- Enhanced Recovery After Surgery
- Hip and Femur Fractures
- COVID-19 and healthcare impacts
- Anesthesia and Neurotoxicity Research
- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Intensive Care Unit Cognitive Disorders
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Healthcare cost, quality, practices
- Cardiac Structural Anomalies and Repair
- Nitric Oxide and Endothelin Effects
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Blood transfusion and management
- Cardiovascular Function and Risk Factors
- Aortic aneurysm repair treatments
- Surgical site infection prevention
- Healthcare Policy and Management
- Airway Management and Intubation Techniques
- Cardiac Health and Mental Health
Baystate Health
2019-2025
University of Massachusetts Chan Medical School
2016-2025
Baystate Medical Center
2015-2024
English Heritage
2023
Charlottesville Medical Research
2023
New York Proton Center
2023
Digital Scholar (United States)
2023
Society of Thoracic Surgeons
2020-2022
Springfield College
2021
Centerforce
2020
In 2012, Kidney Disease: Improving Global Outcomes (KDIGO) published a guideline on the classification and management of acute kidney injury (AKI). The was derived from evidence available through February 2011. Since then, new has emerged that important implications for clinical practice in diagnosing managing AKI. April 2019, KDIGO held controversies conference entitled Acute Injury with following goals: determine best practices areas uncertainty treating AKI; review key relevant literature...
Enhanced Recovery After Surgery (ERAS) programs have been shown to lessen surgical insult, promote recovery, and improve postoperative clinical outcomes across a number of specialty operations. A core tenet ERAS involves the provision protocolized evidence-based perioperative interventions. Given both growing enthusiasm for applying principles cardiac surgery broad scope relevant interventions, an international, multidisciplinary expert panel was assembled derive list potential program...
In the setting of current novel coronavirus pandemic, this document has been generated to provide guiding statements for adult cardiac surgeon consider in a rapidly evolving national landscape. Acknowledging risk potentially prolonged need surgery procedure deferral, we have created proposed template physicians and interdisciplinary teams protecting their patients, institution, highly specialized team. addition, recommendations on transition from traditional in-person patient assessments...
Opioid-based anesthesia and analgesia is a traditional component of perioperative care for the cardiac surgery patient. Growing enthusiasm Enhanced Recovery Programs (ERPs) coupled with evidence potential harm associated high-dose opioids suggests that we reconsider role in surgery.An interdisciplinary North American panel experts, using structured appraisal literature modified Delphi method, derived consensus recommendations optimal pain management opioid stewardship patients. Individual...
Studies have shown that the diabetic heart exhibits abnormalities in cellular ion transport, which can affect susceptibility to reperfusion-induced ventricular fibrillation (VF), tachycardia (VT) and functional derangements. It has been "preconditioning" renders very resistant a subsequent prolonged ischemic episode. This phenomenon extensively studied healthy myocardium, but such study not previously done diseased (hypertrophic or myopathic) hearts.We incidence of VF, VT, cardiac function,...
The first FDA-approved test to assess risk for acute kidney injury (AKI), [TIMP-2]•[IGFBP7], is clinically available in many parts of the world, including USA and Europe. We sought understand how currently being used clinically.We invited a group experts knowledgeable on utility this panel discussion regarding appropriate use test. Specifically, we wanted identify which patients would be testing, results are interpreted, what actions taken based modified Delphi method prioritize specific...
The aim was to examine whether intracellular antioxidants play a role in myocardial preservation following hypoxic preconditioning.Isolated working rat hearts were subjected 30 min ischaemia and reperfusion. Control compared preconditioned with 10 hypoxia. Left ventricular function lactate dehydrogenase (LDH) release measured each group. Ascorbate dependent (ADAR) thiol (TDAR) components of the endogenous antioxidant reserve assessed using electron spin resonance spectroscopy.a Hypoxic...
Objective: Several recent studies have implicated a role of endogenous nitric oxide (NO) in the pathophysiology myocardial ischemic/reperfusion injury. However, mechanism by which NO exerts its beneficial/detrimental effects remains unknown. This study examined intracellular signaling studying NO-cGMP pathway on phospho-diesteratic breakdown and turnover phosphoinositides during ischemia reperfusion. Methods: Isolated working rat hearts were made ischemic for 30 min followed A separate group...
Chronic kidney disease (CKD) affects about 10% of all populations worldwide, with 2 million people requiring dialysis. Although patients CKD are at high risk cardiovascular and events, they often underrepresented or excluded in clinical trials, leading to important knowledge gaps how treat these patients. KDIGO (Kidney Disease: Improving Global Outcomes) convened the fourth Controversies Conference on heart, vasculature Dublin, Ireland, February 2020, entitled Central Peripheral Arterial...
BackgroundPostoperative atrial fibrillation (POAF) is a prevalent complication following cardiac surgery that associated with increased adverse events. Several guidelines and expert consensus documents have been published addressing the prevention management of POAF. We aimed to develop an order set facilitate widespread implementation adoption evidence-based practices for POAF surgery.MethodsSubject matter experts were consulted translate existing literature into sample turnkey (TKO) Orders...
AS has received consulting fees from CSL Vifor, Pharmacosmos, Accumen, I-Sep, Grifols, Lindis Corp, Octapharma, HbO2 Therapeutics LLC, and served on the Data Safety Monitoring Board for RAPIDIRON trial. MJ declares no related conflicts of interest. KMT PBMe.Solutions, honoraria Even Troop, travel support attending meeting IFPBM. LSL fee Behring Vifor been board member in Society Cardiovascular Anesthesiologists, National Echocardiography Advancement Patient Blood Management. NA lectures...