- Mechanical Circulatory Support Devices
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Cardiac Arrest and Resuscitation
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac and Coronary Surgery Techniques
- Heart Failure Treatment and Management
- Hip and Femur Fractures
- Respiratory Support and Mechanisms
- Atrial Fibrillation Management and Outcomes
- Enhanced Recovery After Surgery
- COVID-19 and healthcare impacts
- Transplantation: Methods and Outcomes
- Congenital Heart Disease Studies
- COVID-19 Clinical Research Studies
- Healthcare Policy and Management
- Tracheal and airway disorders
- Infectious Aortic and Vascular Conditions
- Organ Transplantation Techniques and Outcomes
- Emergency and Acute Care Studies
- Acute Kidney Injury Research
- Cardiac pacing and defibrillation studies
Baylor College of Medicine
2018-2025
Cardiovascular Institute Hospital
2018-2024
St. Luke's Medical Center
2018-2024
Society of Thoracic Surgeons
2022
St. Luke's Hospital
2018-2021
St. Luke's Hospital
2019-2021
University of Houston
2021
Yale University
2021
Tufts Medical Center
2020
Mount Sinai Medical Center
2019
Enhanced Recovery After Surgery (ERAS) programs have been shown to lessen surgical insult, promote recovery, and improve postoperative clinical outcomes across a number of specialty operations. A core tenet ERAS involves the provision protocolized evidence-based perioperative interventions. Given both growing enthusiasm for applying principles cardiac surgery broad scope relevant interventions, an international, multidisciplinary expert panel was assembled derive list potential program...
There are limited data on the use of extracorporeal membrane oxygenation (ECMO) for pregnant and peripartum women with COVID-19 associated acute respiratory distress syndrome (ARDS). Pregnant may exhibit more severe infections COVID-19, requiring intensive care. We supported nine or ARDS ECMO, all surviving suffering no major complications from ECMO. Our case series demonstrates high-maternal survival rates ECMO support in management ARDS, highlighting that these postpartum patients should...
Abstract: Postoperative atrial fibrillation (POAF) after cardiac surgery is associated with elevated morbidity and mortality. Although current prediction models have limited efficacy, several perioperative interventions can reduce patients' risk of POAF. These begin preoperative medications, including beta-blockers amiodarone. Moreover, patients should be screened for preexisting (AF) so that concomitant surgical ablation left appendage occlusion performed in appropriate candidates....
Bleeding complications are common with extracorporeal membrane oxygenation (ECMO). We investigated whether a heparin monitoring protocol using activated partial thromboplastin time (aPTT) and thromboelastography (TEG) affected clinical outcomes.This retrospective chart review stratified cohorts by study interval: pre-protocol (January 2016-March 2017) or post-protocol (March 2017-December 2017). The defined therapeutic anticoagulation as aPTT of 60-80 seconds TEG reaction (TEG-R) 2-4×...
The present study investigated outcomes in patients with vasoplegia after cardiac surgery treated angiotensin II plus standard-of-care vasopressors. Vasoplegia is a common complication cardiopulmonary bypass and associated significant morbidity mortality. Approximately 250,000 surgeries are performed the United States annually, occurring 20%to-27% of patients.Post-hoc analysis Angiotensin for Treatment High-Output Shock (ATHOS-3) study.Multicenter, multinational study.Sixteen were...
Background— Despite advances in surgical and percutaneous coronary revascularization, ongoing ischemia that is not amenable to standard revascularization techniques a major cause of morbidity mortality. Hepatocyte Growth Factor (HGF) has potent angiogenic anti-apoptotic activities, this study evaluated the functional biochemical effects HGF gene transfer rat model postinfarction heart failure. Methods Results— Lewis rats underwent ligation left anterior descending artery with direct...
Apoptosis secondary to acute ischemia and chronic remodeling is implicated as a mediator of heart failure. This study was designed assess the effect in vivo viral gene transfer anti-apoptotic factor Bcl-2 block apoptosis preserve ventricular geometry function.In rabbit model regional followed by reperfusion, an experimental group treated with adeno-Bcl-2 compared control receiving empty vector adeno-null. Function assessed echocardiography, sonomicrometry border zone normal left ventricle...
BackgroundPostoperative atrial fibrillation (POAF) is a prevalent complication following cardiac surgery that associated with increased adverse events. Several guidelines and expert consensus documents have been published addressing the prevention management of POAF. We aimed to develop an order set facilitate widespread implementation adoption evidence-based practices for POAF surgery.MethodsSubject matter experts were consulted translate existing literature into sample turnkey (TKO) Orders...
BackgroundThe use of extracorporeal membrane oxygenation (ECMO) has expanded and is now widely applied to perioperative care in lung transplant. Respiratory failure after transplant a clinical challenge where ECMO plays critical role.MethodsThe Extracorporeal Life Support Organization registry was queried for patients 18 years older who were treated with 2010-2022. runs more than 24 hours included regardless the timing initiation. Univariable analyses performed compare procedural patient...
Objectives There are multiple published guidelines regarding comprehensive patient blood management, centered on the three pillars of manage preoperative anemia, minimize loss, and tolerate intra/postoperative anemia. We sought to create an order set facilitate widespread implementation evidence-based cardiac surgery management. Methods Subject matter experts were consulted translate existing literature into a sample turnkey for Orders derived from consistent Class I, IIA, or equivalent...