A5079718233- Dialysis and Renal Disease Management
- Acute Kidney Injury Research
- Muscle and Compartmental Disorders
- COVID-19 Clinical Research Studies
- Central Venous Catheters and Hemodialysis
- Sepsis Diagnosis and Treatment
- COVID-19 and healthcare impacts
- Cardiac Arrest and Resuscitation
- Chronic Kidney Disease and Diabetes
- Renal function and acid-base balance
- Public Health in Brazil
- Antibiotics Pharmacokinetics and Efficacy
- Poisoning and overdose treatments
- Long-Term Effects of COVID-19
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Antimicrobial Resistance in Staphylococcus
- Intensive Care Unit Cognitive Disorders
- Electrolyte and hormonal disorders
- Clinical Nutrition and Gastroenterology
- Health Systems, Economic Evaluations, Quality of Life
- Vascular Procedures and Complications
- Hemodynamic Monitoring and Therapy
- Biochemical and Molecular Research
- PI3K/AKT/mTOR signaling in cancer
- Bacterial Identification and Susceptibility Testing
Universidade Estadual Paulista (Unesp)
2016-2025
Universidade de São Paulo
2012-2024
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2004-2024
Universidade de Santa Cruz do Sul
2024
Microsoft (Brazil)
2024
Medecell (Brazil)
2005-2024
University of Valparaíso
2024
Finis Terrae University
2023
Hospital Clínico de la Universidad de Chile
2022
Columbus Oncology and Hematology Associates
2022
In 2012, Kidney Disease: Improving Global Outcomes (KDIGO) published a guideline on the classification and management of acute kidney injury (AKI). The was derived from evidence available through February 2011. Since then, new has emerged that important implications for clinical practice in diagnosing managing AKI. April 2019, KDIGO held controversies conference entitled Acute Injury with following goals: determine best practices areas uncertainty treating AKI; review key relevant literature...
To describe the clinical characteristics, laboratory results, imaging findings, and in-hospital outcomes of COVID-19 patients admitted to Brazilian hospitals.A cohort study laboratory-confirmed who were hospitalized from March 2020 September in 25 hospitals. Data collected medical records using Research Electronic Capture (REDCap) tools. A multivariate Poisson regression model was used assess risk factors for mortality.For a total 2,054 (52.6% male; median age 58 years), mortality 22.0%;...
Summary Background and objectives Peritoneal dialysis is still used for AKI in developing countries despite concerns about its limitations. The objective of this study was to explore the role high-volume peritoneal patients relation metabolic fluid control, outcome, risk factors associated with death. Design, setting, participants, & measurements A prospective performed on 204 who were assigned (prescribed Kt/V=0.60/session) by flexible catheter cycler; 150 (80.2%) included final...
(1) Peritoneal dialysis (PD) should be considered a suitable modality for treatment of acute kidney injury (AKI) in all settings (1B).(2.1) Flexible peritoneal catheters used where resources and expertise exist (1B) (optimal).(2.2) Rigid improvised using nasogastric tubes other cavity drainage may resource-poor environments they still life-saving (1C) (minimum standard).(2.3) We recommend tunnelled to reduce peritonitis peri-catheter leak (practice point).(2.4) that the method catheter...
Peritoneal dialysis (PD) is still widely used for acute renal failure (ARF) in developing countries despite concerns about its inadequacy. Continuous PD has been evaluated ARF by analyzing the resolution of metabolic abnormality and normalization plasma pH, bicarbonate, potassium.A prospective study was performed on 30 patients who were assigned to high-dose continuous (Kt/V = 0.65 per session) via a flexible catheter (Tenckhoff) automated with cycler. Fluid removal, pH control, protein...
Patients who develop acute kidney injury (AKI) in the intensive care unit (ICU) have extremely high rates of mortality and morbidity. The objectives this study were to compare clinical laboratory characteristics AKI patients evaluated not by nephrologists ICU generate hypothesis relationship between timing nephrology consultation outcome.We explored associations among presence with stay in-ICU 148 at a Brazilian teaching hospital from July 2008 May 2010. Multivariable logistic regression was...
Renal involvement is frequent in COVID-19 (4-37%). This study evaluated the incidence and risk factors of acute kidney injury (AKI) hospitalized patients with COVID-19. Methodology: represents a prospective cohort public tertiary university hospital São Paulo, Brazil, during first 90 days pandemic, followed up until clinical outcome (discharge or death). Results: There were 101 COVID-19, which 51.9% admitted to intensive care unit (ICU). The overall AKI was 50%; 36.8% had hematuria...
Peritoneal dialysis (PD) should be considered a suitable method of renal replacement therapy in acute kidney injury (AKI) patients. This study is the largest cohort providing patient characteristics, clinical practice, patterns and their relationship to outcomes developing country. Its objective was describe main determinants technique survival, including trends over time PD treatment AKI Brazilian prospective which all adult patients on were studied from January/2004 January/2014. For...
Few studies have evaluated the viability and outcomes between peritoneal dialysis (PD) haemodialysis (HD) in urgent-start renal replacement therapy (RRT). This study aimed to compare infectious mechanical complications related PD HD. Secondary were identify risk factors for mortality dialysis.A quasi-experimental with incident patients receiving HD a Brazilian university hospital, July 2014 December 2017. Subjects included individuals final-stage chronic kidney disease who required immediate...
Abstract Background Although dementia has emerged as an important risk factor for severe SARS-CoV-2 infection, results on COVID-19-related complications and mortality are not consistent. We examined the clinical presentations outcomes of COVID-19 in a multicentre cohort in-hospital patients, comparing those with without dementia. Methods This retrospective observational study comprises laboratory-confirmed patients aged ≥ 60 years admitted to 38 hospitals from 19 cities Brazil. Data were...
Resumo Introdução: O início da terapia renal substitutiva (TRS) de modo não planejado em portadores doença crônica (DRC) é situação frequente mundialmente. Nesse cenário, a diálise peritoneal (DP) tem se evidenciado como opção terapêutica comparação à hemodiálise (HD). Na TRS planejada, os custos DP são inferiores aos HD, porém literatura carece dessas análises quando o urgente. Objetivo: Avaliar clínica e economicamente, na perspectiva do Sistema Único Saúde (SUS), estratégia iniciar...
Abstract Introduction: Unplanned initiation of renal replacement therapy (RRT) in chronic kidney disease (CKD) patients is a common situation worldwide. In this scenario, peritoneal dialysis (PD) has emerged as therapeutic option compared to hemodialysis (HD). planned RRT, the costs PD are lower than those HD; however, literature lacks such analyses when urgent. Objective: To clinically and economically evaluate, from perspective Unified Health System (SUS, Sistema Único de Saúde), strategy...
Abstract Background Acute kidney injury (AKI) requiring replacement therapy (KRT) in its most severe forms is a significant complication of patients with COVID-19. The development risk score to predict KRT requirement could optimize health resource allocation. Thus, this study aimed develop and validate the hospitalized COVID-19 from 2020 2022. Area under receiver operating characteristic curve for 2021-2022 validation MMCD Methods This multicenter retrospective cohort consecutive COVID-19,...
The definition of adequate dialysis in acute renal failure (ARF) is complex and involves the time referral to dialysis, dose, dialytic method. Nephrologist experience with a specific procedure availability different modalities play an important role these choices. There no consensus literature on best method or ideal dose ARF.Peritoneal (PD) used less ARF patients, being replaced by continuous venovenous therapies. However, it should not be discarded as worthless therapeutic option for...