Liliane Souto Pacheco
A5084132150- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Toxoplasma gondii Research Studies
- Parasitic Infections and Diagnostics
- Sex work and related issues
- Venous Thromboembolism Diagnosis and Management
- Education during COVID-19 pandemic
- Orthopedic Infections and Treatments
- Global Health Care Issues
- Orthopaedic implants and arthroplasty
- Microbial infections and disease research
- Vibrio bacteria research studies
- Antibiotic Use and Resistance
- Sepsis Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- Bacillus and Francisella bacterial research
- Public Health in Brazil
- Heme Oxygenase-1 and Carbon Monoxide
- Total Knee Arthroplasty Outcomes
- Healthcare Regulation
- Antibiotic Resistance in Bacteria
- Herpesvirus Infections and Treatments
- Medical Malpractice and Liability Issues
- COVID-19 epidemiological studies
- Healthcare during COVID-19 Pandemic
Hospital Universitário de Santa Maria
2020-2022
Universidade Federal de Santa Maria
2020-2022
Hospital Nossa Senhora da Conceição
2012-2016
Biology of Infection
2012
To describe the clinical characteristics, laboratory results, imaging findings, and in-hospital outcomes of COVID-19 patients admitted to Brazilian hospitals.A cohort study laboratory-confirmed who were hospitalized from March 2020 September in 25 hospitals. Data collected medical records using Research Electronic Capture (REDCap) tools. A multivariate Poisson regression model was used assess risk factors for mortality.For a total 2,054 (52.6% male; median age 58 years), mortality 22.0%;...
Background: Amikacin is still an essential antimicrobial to treat life-threatening infections, including multidrug-resistant microorganisms. The effectiveness of treatment has been correlated with the Cmax/MIC ratio, a ratio 8 being recommended, which difficult reach in some patients. Appropriate antibiotic exposure important for knowing disposition drug population. Objectives: We aimed integrate therapeutic monitoring and populational pharmacokinetic model assess optimal dose regimen...
Toxoplasma gondii is a protozoan that has great genetic diversity and prevalent worldwide. In 2018, an outbreak of toxoplasmosis occurred in Santa Maria, Brazil, which was considered the largest ever described world. This paper describes isolation molecular characterization from placenta two pregnant women with acute who had live births were receiving treatment for during outbreak. For this, placental tissue samples patients underwent by mice bioassay, conventional PCR genotyping using...
The COVID-19 pandemic caused unprecedented pressure over health care systems worldwide. Hospital-level data that may influence the prognosis in patients still needs to be better investigated. Therefore, this study analyzed regional socioeconomic, hospital, and intensive units (ICU) characteristics associated with in-hospital mortality admitted Brazilian institutions. This multicenter retrospective cohort is part of Registry. We enrolled ≥ 18 years old laboratory-confirmed participating...
Toxoplasmosis is a disease caused by T. gondii, protozoa which affects humans and animals widely distributed worldwide. In humans, there great concern due to the serious consequences that can occur in infection of pregnant women newborn. The early diagnosis gestational toxoplasmosis important for treatment be carried out order prevent vertical transmission or reduce damage. made through detection antibodies neonates PCR amniotic fluid. Previous studies have also reported placenta as good...
Background:The COVID-19 pandemic caused unprecedented pressure over health care systems, but hospital-level data that may influence the prognosis are not well-studied. Therefore, this study analyzed regional socioeconomic, hospital, and intensive units (ICU) characteristics associated with mortality in patients admitted to Brazilian institutions.Methods:This is a multicenter retrospective cohort. Patients from March September 2020, were enrolled. Data collected through hospital records,...
Introduction: Many patients coinfected with the human immunodeficiency virus (HIV) and hepatitis C (HCV) are using highly active antiretroviral therapy (HAART) HCV peginterferon (PEG-IFN) ribavirina (RBV) because use of direct-acting antivirals is not a reality in some countries. To know impact such medications sustained virological response (SVR) during treatment great importance. Methodology: This was retrospective cohort study 215 HIV/HCV patients. The were treated PEG-IFN RBV between...
INTRODUÇÃO:Brevibacillus brevis (B.brevis) é uma bactéria gram-positiva, aeróbica, bacilo formador de esporos comumente encontrado no solo, ar, água e matéria em decomposição. Raramente associada à doenças infecciosas. Entretanto, pode acometer imunodeprimidos, devido suscetibilidade destes. Nesse cenário, a correta identificação do agente etiológico essencial. Métodos diagnósticos, que não dependam crescimento germe inclusive sejam efetivos quando os patógenos estão viáveis, têm sido...
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Toxoplasmosis is a disease caused by T. gondii, protozoa which affects humans and animals widely distributed worldwide. In humans, there great concern due to the serious consequences that can occur in infection of pregnant women newborn. The early diagnosis gestational toxoplasmosis important for treatment be carried out order prevent vertical transmission or reduce damage. made through detection antibodies neonates PCR amniotic fluid. Previous studies have also reported placenta as good...
Prosthetic joint infection (PJI) is a devastating complication that can affect hip arthroplasty. Its treatment extremely difficult, and issues regarding the optimal remain unanswered. This study intended to show effectiveness of one-stage PJI.A retrospective observational cohort performed from July 2014- August 2018. All patients with suspected PJI were included. Major minor criteria developed by International Consensus on Periprosthetic Joint Infection (ICPJI) was used define infection....
Background: Previous studies that assessed risk factors for venous thromboembolism (VTE) in COVID-19 patients have shown inconsistent results. Our aim was to investigate VTE predictors by both logistic regression (LR) and machine learning (ML) approaches, due their potential complementarity.Methods: This substudy of a large Brazilian Registry included adult from 16 hospitals. Symptomatic confirmed objective imaging. LR analysis, tree-based boosting bagging were used the association variables...