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Leonardo Seixas de Oliveira

ORCID: 0000-0003-1575-6559
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A5065833696
Research Areas
  • COVID-19 and healthcare impacts
  • COVID-19 Clinical Research Studies
  • Machine Learning in Healthcare
  • COVID-19 diagnosis using AI
  • Long-Term Effects of COVID-19
  • Venous Thromboembolism Diagnosis and Management
  • Sepsis Diagnosis and Treatment
  • Global Health Care Issues
  • SARS-CoV-2 and COVID-19 Research
  • Explainable Artificial Intelligence (XAI)
  • Artificial Intelligence in Healthcare
  • COVID-19 epidemiological studies

Santa Rosa Memorial Hospital
 2021-2022

Hospital Santa Paula
 2021

Hospital Ernesto Dornelles
 2021

 Clinical characteristics and outcomes of patients hospitalized with COVID-19 in Brazil: Results from the Brazilian COVID-19 registry
OPENALEX - Publications 
Milena Soriano Marcolino Patrícia Klarmann Ziegelmann Maíra Viana Rego Souza-Silva Israel Júnior Borges do Nascimento Luana Martins Oliveira and 89 more Luanna S. Monteiro Thaís Lorenna Souza Sales Karen Brasil Ruschel Karina Paula Medeiros Prado Martins Ana Paula Beck da Silva Etges Israel Molina Carísi Anne Polanczyk Alexandre Vargas Schwarzbold Amanda de Oliveira Maurílio A. L. F. de Barros Ana Luiza Bahia Alves Scotton Alfonso J. Rodríguez‐Morales Anderson Lacerda dos Reis André S. Costa Argenil José Assis de Oliveira Bárbara Lopes Farace Carla Thaís Cândida Alves da Silva Carolina Marques Ramos Christiane Corrêa Rodrigues Cimini Cíntia Alcântara de Carvalho Daniel Vitório Silveira Daniela Ponce Emanuele Marianne Souza Kroger Euler Roberto Fernandes Manenti Fernanda Barbosa Lucas Fernanda d’Athayde Rodrigues Fernando Anschau Fernando Antônio Botoni Frederico Bartolazzi Gabriela Petry Crestani Guilherme Fagundes Nascimento Helena Carolina Noal Helena Duani Heloísa Reniers Vianna Henrique Cerqueira Guimarães Joice Coutinho de Alvarenga Júlia Drumond Parreiras de Morais Juliana Machado-Rugolo Lara Monalyza Gonçalves Franco Leila Beltrami Moreira Leonardo Seixas de Oliveira Lílian Santos Pinheiro Liliane Souto Pacheco Luciane Kopittke Luciano de Souza Viana Luis Cesar Souto de Moura Luísa Elem Almeida Santos Máderson Alvares de Souza Cabral Maíra Dias Souza Marcela Gonçalves Trindade Tofani Marconi Franco da Silveira Marcus Vinícius Melo de Andrade Maria Angélica Pires Ferreira Maria Aparecida Camargos Bicalho Maria Auxiliadora Parreiras Martins Maria Clara Pontello Barbosa Lima Mariana Balbinot Borges Mariana de Braga Lima Carvalho Canesso Matheus Carvalho Alves Nogueira Meire Pereira de Figueiredo Milton Henriques Guimarães Júnior Mychelle Stefany Santos Almeida Mônica Aparecida de Paula de Sordi Natália da Cunha Severino Sampaio Neimy Ramos de Oliveira Paulo Tarso Lima Vianna Pedro Guido Soares Andrade Pedro Ledic Assaf Rafael Fusaro Aguiar Oliveira Rafael Lima Rodrigues de Carvalho Rafaela dos Santos Charão de Almeida Raphael Castro Martins Reginaldo Aparecido Valácio Ricardo Bertoglio Cardoso Ricardo Braga Coelho Roberta Pozza Rodolfo Lucas Silva Mourato Rodrigo Costa Pereira Vieira Roger Mendes de Abreu Rufino de Freitas Silva Saionara Cristina Francisco Silvana Mangeon Mereilles Guimarães Silvia Ferreira Araújo Talita Fischer Oliveira Tatiana de Vargas Tatiani Oliveira Fereguetti Thalita Martins Lage Thulio Henrique Oliveira Diniz Veridiana Baldon dos Santos

To describe the clinical characteristics, laboratory results, imaging findings, and in-hospital outcomes of COVID-19 patients admitted to Brazilian hospitals.A cohort study laboratory-confirmed who were hospitalized from March 2020 September in 25 hospitals. Data collected medical records using Research Electronic Capture (REDCap) tools. A multivariate Poisson regression model was used assess risk factors for mortality.For a total 2,054 (52.6% male; median age 58 years), mortality 22.0%;...

10.1016/j.ijid.2021.01.019 article EN cc-by-nc-nd International Journal of Infectious Diseases 2021-01-14
 ABC2-SPH risk score for in-hospital mortality in COVID-19 patients: development, external validation and comparison with other available scores
OPENALEX - Publications 
Milena Soriano Marcolino Magda Carvalho Pires Lucas Emanuel Ferreira Ramos Rafael T. Silva Luana Martins Oliveira and 95 more Rafael Lima Rodrigues de Carvalho Rodolfo Lucas Silva Mourato Adrián Sánchez‐Montalvá Berta Raventós Fernando Anschau José Miguel Chatkin Matheus Carvalho Alves Nogueira Milton Henriques Guimarães Júnior Giovanna Grünewald Vietta Helena Duani Daniela Ponce Patrícia Klarmann Ziegelmann Luís César de Castro Karen Brasil Ruschel Christiane Corrêa Rodrigues Cimini Saionara Cristina Francisco Maiara Anschau Floriani Guilherme Fagundes Nascimento Bárbara Lopes Farace Luanna S. Monteiro Maíra Viana Rego Souza-Silva Thaís Lorenna Souza Sales Karina Paula Medeiros Prado Martins Israel Júnior Borges do Nascimento Tatiani Oliveira Fereguetti Daniel T. M. O. Ferrara Fernando Antônio Botoni Ana Paula Beck da Silva Etges Alexandre Vargas Schwarzbold Amanda O. Maurílio Ana Luiza Bahia Alves Scotton André P. Weber André S. Costa Andressa Barreto Glaeser Angélica Aparecida Coelho Madureira Angelinda Rezende Bhering Bruno Mateus de Castro Carla Thais C.A. da Silva Carolina Marques Ramos Caroline Danubia Gomes Cíntia Alcântara de Carvalho Daniel Vitório Silveira Edilson Cezar Elayne Crestani Pereira Emanuele Marianne Souza Kroger Felipe Barbosa Vallt Fernanda Barbosa Lucas Fernando Graça Aranha Frederico Bartolazzi Gabriela Petry Crestani Gisele Alsina Nader Bastos Glícia Cristina de Castro Madeira Helena Carolina Noal Heloísa Reniers Vianna Henrique Cerqueira Guimarães Isabela Moraes Gomes Israel Molina Joanna d’Arc Lyra Batista Joice Coutinho de Alvarenga Júlia di Sabatino Santos Guimarães Júlia Drumond Parreiras de Morais Juliana Machado-Rugolo Karen Cristina J.R. Pontes Kauane Aline Maciel dos Santos Leonardo Seixas de Oliveira Lílian Santos Pinheiro Liliane Souto Pacheco Lucas de Deus Sousa Luciana Siuves Ferreira Couto Luciane Kopittke Luis Cesar Souto de Moura Luísa Elem Almeida Santos Máderson A.S. Cabral Maíra Dias Souza Marcela Gonçalves Trindade Tofani Marcelo Carneiro Maria Angélica Pires Ferreira Maria Aparecida Camargos Bicalho Maria Clara Pontello Barbosa Lima Mariana Frizzo de Godoy Marília Mastrocolla de Almeida Cardoso Meire Pereira de Figueiredo Natália C.S. Sampaio Natália L. Rangel Natália T. Crespo Neimy Ramos de Oliveira Pedro Ledic Assaf Petrônio José de Lima Martelli Rafaela Santos Charão de Almeida Raphael Castro Martins Raquel Lutkmeier Reginaldo Aparecido Valácio Renan Goulart Finger Ricardo Bertoglio Cardoso Roberta Pozza

10.1016/j.ijid.2021.07.049 article EN cc-by-nc-nd International Journal of Infectious Diseases 2021-07-24
 Potential and limitations of machine meta-learning (ensemble) methods for predicting COVID-19 mortality in a large inhospital Brazilian dataset
OPENALEX - Publications 
Bruno Barbosa Miranda de Paiva Polianna Delfino-Pereira Cláudio Moisés Valiense de Andrade Virgínia Mara Reis Gomes Maíra Viana Rego Souza-Silva and 93 more Karina Paula Medeiros Prado Martins Thaís Lorenna Souza Sales Rafael Lima Rodrigues de Carvalho Magda Carvalho Pires Lucas Emanuel Ferreira Ramos Rafael Tavares Silva Alessandra de Freitas Martins Vieira Aline Gabrielle Sousa Nunes Alzira de Oliveira Jorge Amanda de Oliveira Maurílio Ana Luiza Bahia Alves Scotton Carla Thaís Cândida Alves da Silva Christiane Corrêa Rodrigues Cimini Daniela Ponce Elayne Crestani Pereira Euler Roberto Fernandes Manenti Fernanda d’Athayde Rodrigues Fernando Anschau Fernando Antônio Botoni Frederico Bartolazzi Genna Maira Santos Grizende Helena Carolina Noal Helena Duani Isabela Moraes Gomes Jamille Hemétrio Salles Martins Costa Júlia di Sabatino Santos Guimarães Júlia Teixeira Tupinambás Juliana Machado-Rugolo Joanna d’Arc Lyra Batista Joice Coutinho de Alvarenga José Miguel Chatkin Karen Brasil Ruschel Liege Barella Zandoná Lílian Santos Pinheiro Luanna Silva Monteiro Menezes Lucas Moysés Carvalho de Oliveira Luciane Kopittke Luisa Argolo Assis Luiza Margoto Marques Magda César Raposo Maiara Anschau Floriani Maria Aparecida Camargos Bicalho Matheus Carvalho Alves Nogueira Neimy Ramos de Oliveira Patrícia Klarmann Ziegelmann Pedro Gibson Paraíso Petrônio José de Lima Martelli Roberta Senger Rochele Mosmann Menezes Saionara Cristina Francisco Silvia Ferreira Araújo Tatiana Kurtz Tatiani Oliveira Fereguetti Thainara Conceição de Oliveira Yara Cristina Neves Marques Barbosa Ribeiro Yuri Carlotto Ramires Maria Clara Pontello Barbosa Lima Marcelo Carneiro Adriana Falangola Benjamin Bezerra Alexandre Vargas Schwarzbold André Soares de Moura Costa Bárbara Lopes Farace Daniel Vitório Silveira Evelin Paola de Almeida Cenci Fernanda Barbosa Lucas Fernando Graça Aranha Gisele Alsina Nader Bastos Giovanna Grünewald Vietta Guilherme Fagundes Nascimento Heloísa Reniers Vianna Henrique Cerqueira Guimarães Júlia Drumond Parreiras de Morais Leila Beltrami Moreira Leonardo Seixas de Oliveira Lucas de Deus Sousa Luciano de Souza Viana Máderson Alvares de Souza Cabral Maria Angélica Pires Ferreira Mariana Frizzo de Godoy Meire Pereira de Figueiredo Milton Henriques Guimarães Júnior Mônica Aparecida de Paula de Sordi Natália da Cunha Severino Sampaio Pedro Ledic Assaf Raquel Lutkmeier Reginaldo Aparecido Valácio Renan Goulart Finger Rufino de Freitas Silvana Mangeon Meirelles Guimarães Talita Fischer Oliveira Thulio Henrique Oliveira Diniz Marcos André Gonçalves Milena Soriano Marcolino

Abstract The majority of early prediction scores and methods to predict COVID-19 mortality are bound by methodological flaws technological limitations (e.g., the use a single model). Our aim is provide thorough comparative study that tackles those issues, considering multiple techniques build models, including modern machine learning (neural) algorithms traditional statistical techniques, as well meta-learning (ensemble) approaches. This used dataset from multicenter cohort 10,897 adult...

10.1038/s41598-023-28579-z article EN cc-by Scientific Reports 2023-03-01
 Hospital characteristics associated with COVID-19 mortality: data from the multicenter cohort Brazilian Registry
OPENALEX - Publications 
Maíra Viana Rego Souza-Silva Patrícia Klarmann Ziegelmann Vandack Nobre Virgínia Mara Reis Gomes Ana Paula Beck da Silva Etges and 82 more Alexandre Vargas Schwarzbold Aline Gabrielle Sousa Nunes Amanda de Oliveira Maurílio Ana Luiza Bahia Alves Scotton André Soares de Moura Costa Andressa Barreto Glaeser Bárbara Lopes Farace Bruno Nunes Ribeiro Carolina Marques Ramos Christiane Corrêa Rodrigues Cimini Cíntia Alcântara de Carvalho Claudete Rempel Daniel Vitório Silveira Daniela dos Reis Carazai Daniela Ponce Elayne Crestani Pereira Emanuele Marianne Souza Kroger Euler Roberto Fernandes Manenti Evelin Paola de Almeida Cenci Fernanda Barbosa Lucas Fernanda Costa dos Santos Fernando Anschau Fernando Antônio Botoni Fernando Graça Aranha Filipe Carrilho de Aguiar Frederico Bartolazzi Gabriela Petry Crestani Giovanna Grünewald Vietta Guilherme Fagundes Nascimento Helena Carolina Noal Helena Duani Heloísa Reniers Vianna Henrique Cerqueira Guimarães Joice Coutinho de Alvarenga José Miguel Chatkin Júlia Drumond Parreiras de Morais Juliana da Silva Nogueira Carvalho Juliana Machado-Rugolo Karen Brasil Ruschel Lara de Barros Wanderley Gomes Leonardo Seixas de Oliveira Liege Barella Zandoná Lílian Santos Pinheiro Liliane Souto Pacheco Luanna Silva Monteiro Menezes Lucas de Deus Sousa Luis Cesar Souto de Moura Luísa Elem Almeida Santos Luiz Antônio Nasi Máderson Alvares de Souza Cabral Maiara Anschau Floriani Maíra Dias Souza Marcelo Carneiro Mariana Frizzo de Godoy Marília Mastrocolla de Almeida Cardoso Matheus Carvalho Alves Nogueira Mauro Oscar Soares de Souza Lima Meire Pereira de Figueiredo Milton Henriques Guimarães Júnior Natália da Cunha Severino Sampaio Neimy Ramos de Oliveira Pedro Guido Soares Andrade Pedro Ledic Assaf Petrônio José de Lima Martelli Raphael Castro Martins Reginaldo Aparecido Valácio Roberta Pozza Rochele Mosmann Menezes Rodolfo Lucas Silva Mourato Roger Mendes de Abreu Rufino de Freitas Silva Saionara Cristina Francisco Silvana Mangeon Mereilles Guimarães Silvia Ferreira Araújo Talita Fischer Oliveira Tatiana Kurtz Tatiani Oliveira Fereguetti Thainara Conceição de Oliveira Yara Cristina Neves Marques Barbosa Ribeiro Yuri Carlotto Ramires Carísi Anne Polanczyk Milena Soriano Marcolino

The COVID-19 pandemic caused unprecedented pressure over health care systems worldwide. Hospital-level data that may influence the prognosis in patients still needs to be better investigated. Therefore, this study analyzed regional socioeconomic, hospital, and intensive units (ICU) characteristics associated with in-hospital mortality admitted Brazilian institutions. This multicenter retrospective cohort is part of Registry. We enrolled ≥ 18 years old laboratory-confirmed participating...

10.1007/s11739-022-03092-9 article EN other-oa Internal and Emergency Medicine 2022-09-25
 Predictors of venous thromboembolism in COVID-19 patients: results of the COVID-19 Brazilian Registry
OPENALEX - Publications 
Warley Cezar da Silveira Lucas Emanuel Ferreira Ramos Rafael Tavares Silva Bruno Barbosa Miranda de Paiva Polianna Delfino-Pereira and 52 more Alexandre Vargas Schwarzbold Andresa Fontoura Garbini Bruna Schettino Morato Barreira Bruno Mateus de Castro Carolina Marques Ramos Caroline Danubia Gomes Christiane Corrêa Rodrigues Cimini Elayne Crestani Pereira Eliane Würdig Roesch Emanuele Marianne Souza Kroger Felipe Ferraz Martins Graça Aranha Fernando Anschau Fernando Antônio Botoni Fernando Graça Aranha Gabriela Petry Crestani Giovanna Grünewald Vietta Gisele Alsina Nader Bastos Jamille Hemétrio Salles Martins Costa Jéssica Rayane Corrêa Silva da Fonseca Karen Brasil Ruschel Leonardo Seixas de Oliveira Lílian Santos Pinheiro Liliane Souto Pacheco Luciana Borges Segala Luciana Siuves Ferreira Couto Luciane Kopittke Maiara Anschau Floriani Majlla Magalhães Silva Marcelo Carneiro Maria Angélica Pires Ferreira Maria Auxiliadora Parreiras Martins Marina Neves Zerbini de Faria Matheus Carvalho Alves Nogueira Milton Henriques Guimarães Júnior Natália da Cunha Severino Sampaio Neimy Ramos de Oliveira Nicole de Moraes Pertile Pedro Guido Soares Andrade Pedro Ledic Assaf Reginaldo Aparecido Valácio Rochele Mosmann Menezes Saionara Cristina Francisco Silvana Mangeon Meirelles Guimarães Silvia Ferreira Araújo Suely Meireles Rezende Susany Anastácia Pereira Tatiana Kurtz Tatiani Oliveira Fereguetti Carísi Anne Polanczyk Magda Carvalho Pires Marcos André Gonçalves Milena Soriano Marcolino

10.1007/s11739-022-03002-z article EN Internal and Emergency Medicine 2022-06-01
 Dados de Vida Real sobre o Uso da Hidroxicloroquina ou da Cloroquina Combinadas ou Não à Azitromicina em Pacientes com Covid-19: Uma Análise Retrospectiva no Brasil
OPENALEX - Publications 
Maíra Viana Rego Souza-Silva Daniella Nunes Pereira Magda Carvalho Pires Isabela Muzzi Vasconcelos Alexandre Vargas Schwarzbold and 24 more Diego Henrique de Vasconcelos Elayne Crestani Pereira Euler Roberto Fernandes Manenti Felício Roberto Costa Filipe Carrilho de Aguiar Fernando Anschau Frederico Bartolazzi Guilherme Fagundes Nascimento Heloísa Reniers Vianna Joanna d’Arc Lyra Batista Juliana Machado-Rugolo Karen Brasil Ruschel Maria Angélica Pires Ferreira Leonardo Seixas de Oliveira Luanna Silva Monteiro Menezes Patrícia Klarmann Ziegelmann Marcela Gonçalves Trindade Tofani Maria Aparecida Camargos Bicalho Matheus Carvalho Alves Nogueira Milton Henriques Guimarães Júnior Rúbia Laura Oliveira Aguiar Danyelle Romana Alves Rios Carísi Anne Polanczyk Milena Soriano Marcolino

Despite no evidence showing benefits of hydroxychloroquine and chloroquine with or without azithromycin for COVID-19 treatment, these medications have been largely prescribed in Brazil.To assess outcomes, including in-hospital mortality, electrocardiographic abnormalities, hospital length-of-stay, admission to the intensive care unit, need dialysis mechanical ventilation, hospitalized patients who received hydroxychloroquine, compare outcomes between those their matched controls.A...

10.36660/abc.20220935 article PT cc-by-nc Arquivos Brasileiros de Cardiologia 2023-09-01
 Effectiveness, Explainability and Reliability of Machine Meta-Learning Methods for Predicting Mortality in Patients with COVID-19: Results of the Brazilian COVID-19 Registry
OPENALEX - Publications 
Bruno Barbosa Miranda de Paiva Polianna Delfino-Pereira Cláudio Moisés Valiense de Andrade Virgínia Mara Reis Gomes Maria Clara Pontello Barbosa Lima and 88 more Maíra Viana Rego Souza-Silva Marcelo Carneiro Karina Paula Medeiros Prado Martins Thaís Lorenna Souza Sales Rafael Lima Rodrigues de Carvalho Magda Carvalho Pires Lucas Emanuel Ferreira Ramos Rafael T. Silva Adriana Falangola Benjamin Bezerra Alexandre Vargas Schwarzbold Aline Gabrielle Sousa Nunes Amanda de Oliveira Maurílio Ana Luiza Bahia Alves Scotton André Soares de Moura Costa Andriele Abreu Castro Bárbara Lopes Farace Christiane Corrêa Rodrigues Cimini Cíntia Alcântara De Carvalho Daniel Vitório Silveira Daniela Ponce Elayne Crestani Pereira Euler Roberto Fernandes Manenti Evelin Paola de Almeida Cenci Fernanda Barbosa Lucas Fernanda d’Athayde Rodrigues Fernando Anschau Fernando Antônio Botoni Fernando Graça Aranha Frederico Bartolazzi Gisele Alsina Nader Bastos Giovanna Grünewald Vietta Guilherme Fagundes Nascimento Helena Carolina Noal Helena Duani Heloísa Reniers Vianna Henrique Cerqueira Guimarães Isabela Moraes Gomes Jamille Hemétrio Salles Martins Costa Jéssica Rayane Corrêa Silva da Fonseca Júlia Di Sabatino Santos Guimarães Júlia Drumond Parreiras de Morais Juliana Machado-Rugolo Joanna d’Arc Lyra Batista Joice Coutinho de Alvarenga José Miguel Chatkin Karen Brasil Ruschel Leila Beltrami Moreira Leonardo Seixas de Oliveira Liege Barella Zandoná Lílian Santos Pinheiro Luanna da Silva Monteiro Lucas de Deus Sousa Luciane Kopittke Luciano de Souza Viana Luís César de Castro Luisa Argolo Assis Luisa Elem Almeid Santos Máderson Alvares de Souza Cabral Magda César Raposo Maiara Anschau Floriani Maria Angélica Pires Ferreira Maria Aparecida Camargos Bicalho Mariana Frizzo de Godoy Matheus Carvalho Alves Nogueira Meire Pereira de Figueiredo Milton Henriques Guimarães Júnior Mônica Aparecida de Paula de Sordi Natália da Cunha Severino Sampaio Neimy Ramos de Oliveira Pedro Ledic Assaf Raquel Lutkmeier Reginaldo Aparecido Valácio Renan Goulart Finger Roberta Senger Rochele Mosmann Menezes Rufino de Freitas Silva Saionara Cristina Francisco Silvana Mangeon Mereilles Guimarães Silvia Ferreira Araújo Talita Fischer Oliveira Tatiana Kurtz Tatiani Oliveira Fereguetti Thainara Conceição de Oliveira Thulio Henrique Oliveira Diniz Yara Cristina Neves Marques Barbosa Ribeiro Yuri Carlotto Ramires Marcos André Gonçalves Milena Soriano Marcolino

Abstract Objective To provide a thorough comparative study among state-of-the-art machine learning methods and statistical for determining in-hospital mortality in COVID-19 patients using data upon hospital admission; to the reliability of predictions most effective by correlating probability outcome accuracy methods; investigate how explainable are produced methods. Materials Methods De-identified were obtained from positive 36 participating hospitals, March 1 September 30, 2020....

10.1101/2021.11.01.21265527 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2021-11-02
 Hospital Characteristics Associated With COVID-19 Mortality: Data From the Multicenter Cohort Brazilian COVID-19 Registry
OPENALEX - Publications 
Maíra Viana Rego Souza-Silva Patrícia Klarmann Ziegelmann Vandack Nobre Virgínia Mara Reis Gomes Ana Paula Beck da Silva Etges and 82 more Alexandre Vargas Schwarzbold Aline Gabrielle Sousa Nunes Amanda de Oliveira Maurílio Ana Luiza Bahia Alves Scotton André Soares de Moura Costa Andressa Barreto Glaeser Bárbara Lopes Farace Bruno Nunes Ribeiro Carolina Marques Ramos Christiane Corrêa Rodrigues Cimini Cíntia Alcântara de Carvalho Claudete Rempel Daniel Vitório Silveira Daniela dos Reis Carazai Daniela Ponce Elayne Crestani Pereira Emanuele Marianne Souza Kroger Euler Roberto Fernandes Manenti Evelin Paola de Almeida Cenci Fernanda Barbosa Lucas Fernanda Costa dos Santos Fernando Anschau Fernando Antônio Botoni Fernando Graça Aranha Filipe Carrilho de Aguiar Frederico Bartolazzi Gabriela Petry Crestani Giovanna Grünewald Vietta Guilherme Fagundes Nascimento Helena Carolina Noal Helena Duani Heloísa Reniers Vianna Henrique Cerqueira Guimarães Joice Coutinho de Alvarenga José Miguel Chatkin Júlia Drumond Parreiras de Morais Juliana da Silva Nogueira Carvalho Juliana Machado-Rugolo Karen Brasil Ruschel Lara de Barros Wanderley Gomes Leonardo Seixas de Oliveira Liege Barella Zandoná Lílian Santos Pinheiro Liliane Souto Pacheco Luanna da Silva Monteiro Lucas de Deus Sousa Luis Cesar Souto de Moura Luísa Elem Almeida Santos Luiz Antônio Nasi Máderson Alvares de Souza Cabral Maiara Anschau Floriani Maíra Dias Souza Marcelo Carneiro Mariana Frizzo de Godoy Marília Mastrocolla de Almeida Cardoso Matheus Carvalho Alves Nogueira Mauro Oscar Soares de Souza Lima Meire Pereira de Figueiredo Milton Henriques Guimarães Júnior Natália da Cunha Severino Sampaio Neimy Ramos de Oliveira Pedro Guido Soares Andrade Pedro Ledic Assaf Petrônio José de Lima Martelli Raphael Castro Martins Reginaldo Aparecido Valácio Roberta Pozza Rochele Mosmann Menezes Rodolfo Lucas Silva Mourato Roger Mendes de Abreu Rufino de Freitas Silva Saionara Cristina Francisco Silvana Mangeon Mereilles Guimarães Silvia Ferreira Araújo Talita Fischer Oliveira Tatiana Kurtz Tatiani Oliveira Fereguetti Thainara Conceição de Oliveira Yara Cristina Neves Marques Barbosa Ribeiro Yuri Carlotto Ramires Carísi Anne Polanczyk Milena Soriano Marcolino

Background:The COVID-19 pandemic caused unprecedented pressure over health care systems, but hospital-level data that may influence the prognosis are not well-studied. Therefore, this study analyzed regional socioeconomic, hospital, and intensive units (ICU) characteristics associated with mortality in patients admitted to Brazilian institutions.Methods:This is a multicenter retrospective cohort. Patients from March September 2020, were enrolled. Data collected through hospital records,...

10.2139/ssrn.3979651 article EN SSRN Electronic Journal 2021-01-01
 Effectiveness, Explainability and Reliability of Machine Meta-Learning Methods for Predicting Mortality in Patients with COVID-19: Results of the Brazilian COVID-19 Registry
OPENALEX - Publications 
Polianna Delfino-Pereira Cláudio Moisés Valiense de Andrade Virgínia Mara Reis Gomes Maria Clara Pontello Barbosa Lima Maíra Viana Rego Souza-Silva and 87 more Marcelo Carneiro Karina Paula Medeiros Prado Martins Thaís Lorenna Souza Sales Rafael Lima Rodrigues De Carvalho Magda Carvalho Pires Lucas Emanuel Ferreira Ramos Rafael T. Silva Adriana Falangola Benjamin Bezerra Alexandre Vargas Schwarzbold Aline Gabrielle Sousa Nunes Amanda de Oliveira Maurílio Ana Luiza Bahia Alves Scotton André Soares de Moura Costa Andriele Abreu Castro Bárbara Lopes Farace Christiane Corrêa Rodrigues Cimini Cíntia Alcântara De Carvalho Daniel Vitório Silveira Daniela Ponce Elayne Crestani Pereira Euler Roberto Fernandes Manenti Evelin Paola de Almeida Cenci Fernanda Barbosa Lucas Fernanda d’Athayde Rodrigues Fernando Anschau Fernando Antônio Botoni Fernando Graça Aranha Frederico Bartolazzi Gisele Alsina Nader Bastos Giovanna Grünewald Vietta Guilherme Fagundes Nascimento Helena Carolina Noal Helena Duani Heloísa Reniers Vianna Henrique Cerqueira Guimarães Isabela Moraes Gomes Jamille Hemerito Salles Martins Costa Jessica Rayane Corrêa Silva Da Fonseca Júlia Di Sabatino Santos Guimarães Júlia Drumond Parreiras De Morais Juliana Machado-Rugolo Joanna d’Arc Lyra Batista Joice Coutinho De Alvarenga José Miguel Chatkin Karen Brasil Ruschel Leila Beltrami Moreira Leonardo Seixas de Oliveira Liege Barella Zandoná Lílian Santos Pinheiro Luanna da Silva Monteiro Lucas de Deus Sousa Luciane Kopittke Luciano de Souza Viana Luís César De Castro Luísa Argolo Assis Luísa Elem Almeida Santos Máderson Alvares de Souza Cabral Magda César Raposo Maiara Anschau Floriani Maria Angélica Pires Ferreira Maria Aparecida Camargos Bicalho Mariana Frizzo de Godoy Matheus Carvalho Alves Nogueira Meire Pereira De Figueiredo Milton Henriques Guimarães Júnior Monica Aparecida de Paula De Sordi Natália da Cunha Severino Sampaio Neimy Ramos de Oliveira Pedro Ledic Assaf Raquel Lutkmeier Reginaldo Aparecido Valácio Renan Goulart Finger Rochele Mosmann Menezes Rufino de Freitas Silva Saionara Cristina Francisco Silvana Mangeon Meireles Guimaraes Silvia Ferreira Araújo Talita Fischer Oliveira Tatiana Kurtz Tatiana Oliveira Fereguetti Thainara Conceição De Oliveira Túlio Henrique Oliveira Diniz Yara Cristina Neves Marques Barbosa Ribeiro Yuri Carlotto Ramires Marcos André Gonçalves Milena Soriano Marcolino Bruno Barbosa Miranda de Paiva

Abstract The majority prognostic scores proposed for early assessment of coronavirus disease 19 (COVID-19) patients are bounded by methodological flaws. Our group recently developed a new risk score - ABC 2 SPH using traditional statistical methods (least absolute shrinkage and selection operator logistic regression LASSO). In this article, we provide thorough comparative study between modern machine learning (ML) state-of-the-art methods, represented SPH, in the task predicting in-hospital...

10.21203/rs.3.rs-1164411/v1 preprint EN cc-by Research Square (Research Square) 2022-01-11
 Predictors of Venous Thromboembolism in COVID-19 Patients: Results of the COVID-19 Brazilian Registry
OPENALEX - Publications 
Warley Cezar da Silveira Lucas Emanuel Ferreira Ramos Rafael T. Silva Bruno Barbosa Miranda de Paiva Polianna Delfino-Pereira and 52 more Alexandre Vargas Schwarzbold Andresa Fontoura Garbini Bruna Schettino Morato Barreira Bruno Mateus de Castro Carolina Marques Ramos Caroline Danubia Gomes Christiane Corrêa Rodrigues Cimini Elayne Crestani Pereira Eliane Würdig Roesch Emanuele Marianne Souza Kroger Felipe Ferraz Martins Graça Aranha Fernando Anschau Fernando Antônio Botoni Fernando Graça Aranha Gabriela Petry Crestani Giovanna Grünewald Vietta Gisele Alsina Nader Bastos Jamille Hemétrio Salles Martins Costa Jéssica Rayane Corrêa Silva da Fonseca Karen Brasil Ruschel Leonardo Seixas de Oliveira Lílian Santos Pinheiro Liliane Souto Pacheco Luciana Borges Segala Luciana Siuves Ferreira Couto Luciane Kopittke Maiara Anschau Floriani Majlla Magalhães Silva Marcelo Carneiro Maria Angélica Pires Ferreira Matheus Carvalho Alves Nogueira Maria Auxiliadora Parreiras Martins Marina Neves Zerbini de Faria Milton Henriques Guimarães Júnior Natália da Cunha Severino Sampaio Neimy Ramos de Oliveira Nicole de Moraes Pertile Pedro Guido Soares Andrade Pedro Ledic Assaf Reginaldo Aparecido Valácio Rochele Mosmann Menezes Saionara Cristina Francisco Silvana Mangeon Mereilles Guimarães Silvia Ferreira Araújo Suely Meireles Rezende Susany Anastácia Pereira Tatiana Kurtz Tatiani Oliveira Fereguetti Carísi Anne Polanczyk Magda Carvalho Pires Marcos André Gonçalves Milena Soriano Marcolino

Background: Previous studies that assessed risk factors for venous thromboembolism (VTE) in COVID-19 patients have shown inconsistent results. Our aim was to investigate VTE predictors by both logistic regression (LR) and machine learning (ML) approaches, due their potential complementarity.Methods: This substudy of a large Brazilian Registry included adult from 16 hospitals. Symptomatic confirmed objective imaging. LR analysis, tree-based boosting bagging were used the association variables...

10.2139/ssrn.3970713 article EN SSRN Electronic Journal 2021-01-01
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