A5033697898- Pharmaceutical Economics and Policy
- Health Systems, Economic Evaluations, Quality of Life
- Cardiomyopathy and Myosin Studies
- Public Health in Brazil
- Trypanosoma species research and implications
- Economic and Financial Impacts of Cancer
- Iron Metabolism and Disorders
- Hemoglobinopathies and Related Disorders
- COVID-19 Clinical Research Studies
- Machine Learning in Healthcare
- Infective Endocarditis Diagnosis and Management
- Intensive Care Unit Cognitive Disorders
- COVID-19 diagnosis using AI
- HIV/AIDS Research and Interventions
- Lysosomal Storage Disorders Research
- Cardiovascular Function and Risk Factors
- Erythropoietin and Anemia Treatment
- Healthcare cost, quality, practices
- Cardiac and Coronary Surgery Techniques
- Long-Term Effects of COVID-19
- Blood properties and coagulation
- Pharmaceutical studies and practices
- Radiation Dose and Imaging
- Science and Education Research
- Adolescent Sexual and Reproductive Health
Universidade Federal de Minas Gerais
2022-2024
Fundação Centro de Hematologia e Hemoterapia de Minas Gerais
2020
Faculdade de Ciências Médicas de Minas Gerais
2017
Despite substantial progress toward its control, Chagas disease continues to be a major public health problem in Latin America and has become global concern. The affects approximately 6 million people, of whom 20-40% will develop cardiomyopathy over the years after initial Trypanosoma cruzi infection. is most serious frequent manifestation disease. Clinical manifestations vary widely according severity myocardial dysfunction, ranging from asymptomatic severe forms, including dilated with...
Abstract The majority of early prediction scores and methods to predict COVID-19 mortality are bound by methodological flaws technological limitations (e.g., the use a single model). Our aim is provide thorough comparative study that tackles those issues, considering multiple techniques build models, including modern machine learning (neural) algorithms traditional statistical techniques, as well meta-learning (ensemble) approaches. This used dataset from multicenter cohort 10,897 adult...
Patients with sickle cell disease (SCD) are at increased risk for cardiovascular complications. Exercise testing is used as a prognostic marker in variety of diseases. However, there lack evidence on exercise SCD patients, particularly regarding its safety, feasibility, and possible role.We the maximal treadmill test to determine safety feasibility patients. Additionally, factors associated duration, well impact exercise-induced changes clinical outcome, were also assessed.One-hundred...
The pharmaceutical landscape has undergone a transformative shift due to emerging technologies, leading projected value of USD 405.52 billion for the global manufacturing market in 2020. Brazil, representing 2% market, boasts comprehensive public health system called Sistema Único de Saúde (SUS), ensuring universal coverage. However, and private sectors Brazil operate independently, with 23% Brazilians possessing insurance plans. Regulated by Brazilian Drug Market...
Introduction In Brazil, equitable access to medications is critical. There are significant pricing disparities between the National Health System and private health care, which influenced by Committee for Technology Incorporation (CONITEC) Law 14.307. This study investigated these disparities, with aim of proposing strategies sustainability in care. Methods analysis compared prices public sectors trastuzumab adalimumab. Public sector were obtained from Prices Database (HPD) Unimed Table...
Introduction Despite medical advancements, endocarditis still results in high mortality rates. Surgery, while often essential, elevates the risk of hyperinflammation, sepsis, and cytokine release. The use a filter to prevent this remains controversial. This study reviewed existing literature assess efficacy filters support its integration into supplementary health services. Methods An exhaustive search MEDLINE, Cochrane Library, Embase, LILACS, CytoSorbents Corporation databases was...
Introduction Informed healthcare policies in Brazil rely on robust health technology assessment (HTA), especially for conditions like non-small cell lung cancer (NSCLC). We present an efficiency frontier analysis to evaluate NSCLC treatments that correlates annual treatment costs with clinical outcomes, offering a systematic approach enhance decision-making the Brazilian context. Methods This quantitative study analyzed drug within system and efficacy data of pivotal studies. The were using...
Introduction Brazil’s public health system serves most of the population, but 25 percent citizens rely on private insurance. The National Regulatory Agency for Private Health Insurance and Plans (ANS) regulates medicine reimbursements, which diverge from sector threshold. In 2022, Committee Technology Incorporation (CONITEC) set a willingness-to-pay benchmark BRL40,000 (USD8,215) per quality-adjusted life-year. ANS has no such benchmark, highlighting pivotal gap in economic evaluations care....
Introdução No momento do registro de um medicamento no Brasil, os dados usados para aprovação são baseados em estudos com uma população específica, o que limita número pessoas poderiam usar medicamento. entanto, é comum a expansão da indicação outras condições clínicas passar tempo. Considerando preços novos medicamentos sem alternativas terapêuticas relativamente altos e não revisados após sua aprovação, impacto financeiro crescente acentuado. Esse estudo teve como objetivo avaliar...
Prompt release of novel pharmaceuticals is very much sought after during critical circumstances to aid patients and society in need. Nonetheless, the expeditious availability these medications may jeopardize well-structured investigations observations. To tackle this concern, regulatory agencies globally have implemented expedited registration procedures. In Brazil, National Health Surveillance Agency (Anvisa) has likewise an process cater who cannot afford wait. The objective study evaluate...