Mariana Frizzo de Godoy
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- COVID-19 diagnosis using AI
- Long-Term Effects of COVID-19
- Dialysis and Renal Disease Management
- Sepsis Diagnosis and Treatment
- Machine Learning in Healthcare
- Muscle and Compartmental Disorders
- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Acute Kidney Injury Research
- COVID-19 and Mental Health
- COVID-19 Impact on Reproduction
- Vitamin D Research Studies
- Data Stream Mining Techniques
- Time Series Analysis and Forecasting
- Thyroid Disorders and Treatments
- COVID-19 epidemiological studies
- Neurological and metabolic disorders
- Metabolism and Genetic Disorders
- Anomaly Detection Techniques and Applications
- Explainable Artificial Intelligence (XAI)
- Palliative Care and End-of-Life Issues
- Non-Invasive Vital Sign Monitoring
- Healthcare Decision-Making and Restraints
Hospital São Lucas da PUCRS
2021-2024
Pontifícia Universidade Católica do Rio Grande do Sul
2022-2023
Abstract Background Although dementia has emerged as an important risk factor for severe SARS-CoV-2 infection, results on COVID-19-related complications and mortality are not consistent. We examined the clinical presentations outcomes of COVID-19 in a multicentre cohort in-hospital patients, comparing those with without dementia. Methods This retrospective observational study comprises laboratory-confirmed patients aged ≥ 60 years admitted to 38 hospitals from 19 cities Brazil. Data were...
Abstract The majority of early prediction scores and methods to predict COVID-19 mortality are bound by methodological flaws technological limitations (e.g., the use a single model). Our aim is provide thorough comparative study that tackles those issues, considering multiple techniques build models, including modern machine learning (neural) algorithms traditional statistical techniques, as well meta-learning (ensemble) approaches. This used dataset from multicenter cohort 10,897 adult...
Abstract Background Acute kidney injury (AKI) is frequently associated with COVID-19, and the need for replacement therapy (KRT) considered an indicator of disease severity. This study aimed to develop a prognostic score predicting KRT in hospitalised COVID-19 patients, assess incidence AKI requirement. Methods part multicentre cohort, Brazilian Registry. A total 5212 adult patients were included between March/2020 September/2020. Variable selection was performed using generalised additive...
It is not clear whether previous thyroid diseases influence the course and outcomes of COVID-19.The study a part multicentric cohort patients with confirmed COVID-19 diagnosis from 37 hospitals. Matching for age, sex, number comorbidities, hospital was performed paired analysis.Of 7,762 COVID-19, 526 had previously diagnosed hypothyroidism were matched controls. The median age 70 years, 68.3% females. prevalence comorbidities similar, except coronary chronic kidney that higher in group...
Background Proper analysis and interpretation of health care data can significantly improve patient outcomes by enhancing services revealing the impacts new technologies treatments. Understanding substantial impact temporal shifts in these is crucial. For example, COVID-19 vaccination initially lowered mean age at-risk patients later changed characteristics those who died. This highlights importance understanding for assessing factors that affect outcomes. Objective study aims to propose...
The COVID-19 pandemic caused unprecedented pressure over health care systems worldwide. Hospital-level data that may influence the prognosis in patients still needs to be better investigated. Therefore, this study analyzed regional socioeconomic, hospital, and intensive units (ICU) characteristics associated with in-hospital mortality admitted Brazilian institutions. This multicenter retrospective cohort is part of Registry. We enrolled ≥ 18 years old laboratory-confirmed participating...
Resumo Fundamento As complicações cardiovasculares da COVID-19 são aspectos importantes patogênese e do prognóstico doença. Evidências papel troponina lesão miocárdica em pacientes hospitalizados com na América Latina ainda escassos. Objetivos Avaliar a como preditor independente de mortalidade hospitalar suporte ventilatório mecânico hospitalizados, registro brasileiro COVID-19. Métodos Este estudo coorte é um subestudo COVID-19, conduzido 31 hospitais brasileiros 17 [...]
To analyze the clinical characteristics and outcomes of admitted patients with hospital- versus community-manifested COVID-19 to evaluate risk factors related mortality in first population.This retrospective cohort included consecutive adult COVID-19, hospitalized between March September 2020. The demographic data, characteristics, were extracted from medical records. Patients hospital-manifested (study group) those (control matched by propensity score model. Logistic regression models used...
To determinate the accuracy of computed tomography (CT) imaging assessed by deep neural networks for predicting need mechanical ventilation (MV) in patients hospitalized with severe acute respiratory syndrome due to coronavirus disease 2019 (COVID-19).This was a retrospective cohort study carried out at two hospitals Brazil. We included CT scans from who were and had COVID-19 confirmed reverse transcription-polymerase chain reaction (RT-PCR). The training set consisted chest examinations 823...
Context COVID-19 induces complex distress across physical, psychological, and social realms palliative care (PC) has the potential to mitigate this suffering significantly. Objectives To describe clinical characteristics outcomes of patients with an indication PC, compared who had no indication, in different pandemic waves. Methods This retrospective multicenter observational cohort included from 40 hospitals, admitted March 2020 August 2022. Patients described their medical records were...
Abstract Background It is not clear whether previous thyroid diseases influence the course and outcomes of COVID-19. The study aims to compare clinical characteristics COVID-19 patients with without hypothyroidism. Methods a part multicentric cohort confirmed diagnosis, including data collected from 37 hospitals. Matching for age, sex, number comorbidities hospital was performed select hypothyroidism paired analysis. Results From 7,762 patients, 526 had previously diagnosed (50%) were...
Abstract Objective To provide a thorough comparative study among state-of-the-art machine learning methods and statistical for determining in-hospital mortality in COVID-19 patients using data upon hospital admission; to the reliability of predictions most effective by correlating probability outcome accuracy methods; investigate how explainable are produced methods. Materials Methods De-identified were obtained from positive 36 participating hospitals, March 1 September 30, 2020....
Background:The COVID-19 pandemic caused unprecedented pressure over health care systems, but hospital-level data that may influence the prognosis are not well-studied. Therefore, this study analyzed regional socioeconomic, hospital, and intensive units (ICU) characteristics associated with mortality in patients admitted to Brazilian institutions.Methods:This is a multicenter retrospective cohort. Patients from March September 2020, were enrolled. Data collected through hospital records,...
<sec> <title>BACKGROUND</title> Proper analysis and interpretation of health care data can significantly improve patient outcomes by enhancing services revealing the impacts new technologies treatments. Understanding substantial impact temporal shifts in these is crucial. For example, COVID-19 vaccination initially lowered mean age at-risk patients later changed characteristics those who died. This highlights importance understanding for assessing factors that affect outcomes. </sec>...
Abstract Background Scientific data regarding the prevalence of COVID-19 neurological manifestations and prognosis in Latin America countries is still lacking. Therefore, study aims to understand SARS-CoV 2 infection Brazilian population its association with patient outcomes, such as in-hospital mortality. Methods This part Registry, a multicentric cohort, including from 37 hospitals. For analysis, patients were grouped according presence self-reported vs. clinically-diagnosed matched...
ABSTRACT Background Acute kidney injury (AKI) is frequently associated with COVID-19 and the need for replacement therapy (KRT) considered an indicator of disease severity. This study aimed to develop a prognostic score predicting KRT in hospitalized patients. Methods part multicentre cohort, Brazilian Registry. A total 5,212 adult patients were included between March/2020 September/2020. We evaluated four categories predictor variables: (1) demographic data; (2) comorbidities conditions at...
Background: Some patients manifest COVID-19 symptoms while admitted for other reasons. Thus, we aimed to analyze clinical characteristics and outcomes of who developed during hospitalization when compared those hospitalized due COVID-19; evaluate the risk factors related mortality in first population.Methods: This retrospective study included adult patients, between March/2020 September/2020. Demographic data, were extracted from medical records. Patients manifested in-hospital (study group)...