A5004153656- Image Retrieval and Classification Techniques
- Medical Image Segmentation Techniques
- Advanced Image and Video Retrieval Techniques
- Pregnancy and preeclampsia studies
- Indian History and Philosophy
- Diabetes Treatment and Management
- Diabetes Management and Research
- AI in cancer detection
- Indian and Buddhist Studies
- Biomedical Text Mining and Ontologies
- Infective Endocarditis Diagnosis and Management
- Peripheral Artery Disease Management
- Birth, Development, and Health
- Radiomics and Machine Learning in Medical Imaging
- Diabetes and associated disorders
- Sepsis Diagnosis and Treatment
- South Asian Cinema and Culture
- Cell Image Analysis Techniques
- Diabetes Management and Education
- Cardiac, Anesthesia and Surgical Outcomes
- Chronic Disease Management Strategies
- Health Systems, Economic Evaluations, Quality of Life
- Gestational Diabetes Research and Management
- Vascular Procedures and Complications
- Dental Radiography and Imaging
Jena University Hospital
2016-2025
Friedrich Schiller University Jena
2016-2025
Center for Clinical Studies
2011-2022
FH Aachen
1998-2022
Federal Roads Office
2019-2022
Universitäts-Herzzentrum Freiburg-Bad Krozingen
2020-2022
Chemnitz University of Technology
2022
Swiss Data Science Center
2021
University Hospital Leipzig
2020
Heidelberg University
2005-2020
Image interpolation techniques often are required in medical imaging for image generation (e.g., discrete back projection inverse Radon transform) and processing such as compression or resampling. Since the ideal function spatially is unlimited, several kernels of finite size have been introduced. This paper compares 1) truncated windowed sine; 2) nearest neighbor; 3) linear; 4) quadratic; 5) cubic B-spline; 6) cubic; g) Lagrange; 7) Gaussian approximation with kernel sizes from 1/spl...
Tertiary lymphoid organs (TLOs) emerge during nonresolving peripheral inflammation, but their impact on disease progression remains unknown. We have found in aged Apoe(-/-) mice that artery TLOs (ATLOs) controlled highly territorialized aorta T cell responses. ATLOs promoted recruitment, primed CD4(+) cells, generated CD4(+), CD8(+), regulatory (Treg) effector and central memory converted naive cells into induced Treg presented antigen by an unusual set of dendritic B cells. Meanwhile,...
Insufficient antimicrobial exposure is associated with worse outcomes in sepsis. We evaluated whether therapeutic drug monitoring (TDM)-guided antibiotic therapy improves outcomes. Randomized, multicenter, controlled trial from January 2017 to December 2019. Adult patients (n = 254) sepsis or septic shock were randomly assigned 1:1 receive continuous infusion of piperacillin/tazobactam dosing guided by daily TDM piperacillin a fixed dose (13.5 g/24 h if eGFR ≥ 20 mL/min). Target plasma...
Background: Cardiac surgery often represents the only treatment option in patients with infective endocarditis (IE). However, IE may lead to a sudden release of inflammatory mediators, which is associated postoperative organ dysfunction. We investigated effect hemoadsorption during on Methods: This multicenter, randomized, nonblinded, controlled trial assigned undergoing cardiac for (integration CytoSorb cardiopulmonary bypass) or control. The primary outcome (change sequential failure...
To develop a general structure for semantic image analysis that is suitable content-based retrieval in medical applications and an architecture its efficient implementation.Stepwise content of images results six layers information modeling incorporating expert knowledge (raw data layer, registered feature scheme object layer). A reference database with 10,000 categorized according to the modality, orientation, body region, biological system used. By means prototypes each category,...
We examined prevalence and progression of retinopathy in dependence on diabetes duration order to estimate the probability progression.In a retrospective cohort-analysis from an academic outpatient department endocrinology metabolic diseases we analyzed 17461 consultations 4513 patients with DM2 1987 2014. 50.3% (n=2272) had at least one documented result funduscopy.25.8% (20.2% non-proliferative, 4.7% proliferative, 0.7% were not classified, 0.1% blindness). The was 1.1% diagnosis, 6.6%...
Consensus regarding biomarkers for detection of infection-related organ dysfunction in the emergency department is lacking. We aimed to identify and validate that could improve risk prediction overt or incipient when added quick Sepsis-related Organ Failure Assessment (qSOFA) as a screening tool.
The widely used DICOM 3.0 imaging protocol specifies optional tags to store specific information on modality and body region within the header: Body Part Examined Anatomic Structure. We investigate whether this can be for automated categorization of medical images, as is an important first step image retrieval. Our survey examines headers generated by four digital modalities (2 CTs, 2 MRIs) in clinical routine at Aachen University Hospital a period months. manufacturing dates range from 1995...
This paper analyzes B-spline interpolation techniques of degree 2, 4, and 5 with respect to all criteria that have been applied evaluate various schemes in a recently published survey on image medical imaging (Lehmann et al., 1999). It is shown high-degree has superior Fourier properties, smallest error, reasonable computing times. Therefore, B-splines are preferable interpolators for numerous applications processing, particularly if high precision required. If no aliasing occurs, this...
Modern communication standards such as Digital Imaging and Communication in Medicine (DICOM) include non-image data for a standardized description of study, patient, or technical parameters. However, these tags are rather roughly structured, ambiguous, often optional. In this paper, we present mono-hierarchical multi-axial classification code medical images emphasize its advantages content-based image retrieval applications (IRMA). Our so called IRMA coding system consists four axes with...
Abdominal symptoms (AS) are a hallmark of the multiorgan-disease cystic fibrosis (CF). However, abdominal involvement in CF is insufficiently understood and, compared to pulmonary manifestation, still receives little scientific attention. Aims were assess and quantify AS relate them laboratory parameters, clinical findings, medical history.A total 131 patients with all ages assessed new CF-specific questionnaire (JenAbdomen-CF score 1.0) on pain non-pain symptoms, disorders appetite, eating,...
Diabet. Med. 28, 872–875 (2011) Abstract Aim There are conflicting data regarding the risk of osteoporosis in patients with Type 1 diabetes. We investigated an association between diabetes, bone mineral density and prevalent fractures. Methods A single‐centre, cross‐sectional study men pre‐menopausal women diabetes ( n = 128) a matched control group 77) was conducted. The primary outcome measure secondary measures were markers metabolism Results Hip total body densities significantly lower...
About half of all carious lesions in primary teeth German 6- to 7-year-old children remain untreated, but no data regarding the clinical consequences untreated dental caries are available. Therefore, this cross-sectional observational study aimed assess prevalence and experience odontogenic infections dentition 5- 8-year-old children. Dental examinations were performed 5-year-old pre-school (n = 496) school 608) living Westphalian Ennepe-Ruhr district. Schools preschools selected by...
This prospective observational trial investigated effects and safety of periodic fasting in subjects with without type 2 diabetes mellitus (T2DM). The primary end point was set as the change fatty liver index (FLI) a surrogate parameter non-alcoholic disease (NAFLD). Six-hundred ninety-seven (38 T2DM) were enrolled. A baseline FLI ≥ 60 (the threshold for liver) found 264 (37.9%). mean duration 8.5 ± 4.0 days (range 6–38). decreased significantly (−14.02 11.67; p < 0.0001), larger effect...
The aim of the study was to determine quantitative T2 values in prostate tissue and evaluate them for detection grading cancer.After approval from local ethics committee, morphological T2-weighted (T2w) images, apparent diffusion coefficient (ADC) maps diffusion-weighted maps, calculated T2w images 75 men (median age, 66.3 years; median PSA, 8.2 ng/mL) were acquired at 3 T magnetic resonance imaging (MRI). Data retrospectively evaluated their distinction between pathologies.Eight hundred...
Abstract The major burden of knee joint osteoarthritis (OA) is pain. Since in elder patients diabetes mellitus an important comorbidity OA, we explored whether the presence has a significant influence on pain intensity at end stage and aimed to identify factors possibly related changes diabetic patients. In 23 47 nondiabetic with OA undergoing total arthroplasty, assessed before operation using “Knee Injury Osteoarthritis Outcome Score”. Furthermore, synovial tissue, fluid (SF), cartilage,...