- Chronic Obstructive Pulmonary Disease (COPD) Research
- Long-Term Effects of COVID-19
- Respiratory Support and Mechanisms
- COVID-19 and Mental Health
- COVID-19 Clinical Research Studies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Intensive Care Unit Cognitive Disorders
- Pleural and Pulmonary Diseases
- Lung Cancer Diagnosis and Treatment
- Tracheal and airway disorders
- Asthma and respiratory diseases
- Atomic and Subatomic Physics Research
- COVID-19 and healthcare impacts
- Cardiovascular and exercise physiology
- Obstructive Sleep Apnea Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Iron Metabolism and Disorders
- Non-Invasive Vital Sign Monitoring
- Ultrasound and Hyperthermia Applications
- Potassium and Related Disorders
- Neutropenia and Cancer Infections
- Frailty in Older Adults
- Neuroscience of respiration and sleep
- Thermal Regulation in Medicine
- Family and Patient Care in Intensive Care Units
Maastricht University Medical Centre
2020-2024
Maastricht University
2019-2024
Ciro
2019-2024
VieCuri Medisch Centrum
2024
University Medical Center
2023
University of Amsterdam
2021
Amsterdam University Medical Centers
2021
Albert Schweitzer Ziekenhuis
1996-1999
Many patients with COVID-19 did not require hospitalisation, nor underwent testing. There is anecdotal evidence that "mild" may complain about persistent symptoms, even weeks after the infection. This suggests symptoms during infection resolve spontaneously. The objective of this study was to assess whether multiple relevant recover following onset in hospitalised and nonhospitalised COVID-19.A total 2113 members two Facebook groups for coronavirus complaints Netherlands Belgium, from a...
Abstract Background An increasing number of subjects are recovering from COVID-19, raising the need for tools to adequately assess course disease and its impact on functional status. We aimed construct validity Post-COVID-19 Functional Status (PCFS) Scale among adult with confirmed presumed COVID-19. Methods Adult who were members an online panel two Facebook groups COVID-19 persistent symptoms, completed survey after onset infection-related symptoms. The intensity symptoms evaluated Utrecht...
It remains unknown whether and to what extent members of online "long COVID" peer support groups remain symptomatic limited over time. Therefore, we aimed evaluate symptoms in long COVID up 6 months after the onset coronavirus disease 2019 (COVID-19)-related symptoms.Demographics, symptoms, health status, work productivity, functional status health-related quality life were assessed about 3 COVID-19-related groups.Data from 239 patients with a confirmed COVID-19 diagnosis (83% women; median...
The psychological impact of COVID-19 can be substantial. However, knowledge about long-term outcomes in patients with is scarce.In this longitudinal, observational study, we aimed to reveal symptoms posttraumatic stress disorder (PTSD) and anxiety depression up 6 months after the onset COVID-19-related confirmed persistent complaints. To demonstrate nonhospitalized patients, further compare these between hospitalized patients.Demographics, PTSD (Trauma Screening Questionnaire [TSQ] ≥6...
The impact of coronavirus disease 2019 (COVID-19) on quality life appears to be highly underestimated, especially in patients who have not been admitted the hospital. Therefore, our aim was assess respiratory-specific addition generic former with confirmed/suspected COVID-19 never Members an online Belgian social support group for persistent complaints, completed survey. five-level EQ-5D (EQ-5D-5L) and Clinical COPD Questionnaire (CCQ) were used life, respectively. Data 210 non-hospitalized...
OBJECTIVES: We performed a comprehensive health assessment in mechanically ventilated coronavirus disease 2019 survivors to assess the impact of respiratory and skeletal muscle injury sustained during ICU stay on physical performance at 3 months following hospital discharge. DESIGN: Preregistered prospective observational cohort study. SETTING: University ICU. PATIENTS: All patients admitted our first European pandemic wave. MEASUREMENTS AND MAIN RESULTS: At after discharge, 46 underwent...
Background Fatigue is the most commonly reported symptom in patients with persistent complaints following COVID-19 (ie, long COVID). Longitudinal studies examining intensity of fatigue and differentiating between physical mental are lacking. Objective The objectives this study were to (1) assess severity over time members online COVID peer support groups, (2) whether these groups experienced fatigue, or both. Methods A 2-wave web-based follow-up was conducted a confirmed diagnosis...
Chronic haemodialysis causes blood loss and iron-deficiency. This can be corrected with intravenous preparations, e.g. sodium ferric-gluconate (FeGl). In two patents complaints of hypotension malaise during FeGl infusion coincided high levels serum iron a calculated transferrin saturation above 100%. Iron toxicity could the cause these complaints. Free is known to aggravate free radicals other reactive oxygen products that are constantly formed in body. We compared four rates regard...
Abstract Background and Objective Both bronchoscopic lung volume reduction with endobronchial valves (BLVR‐EBV) pulmonary rehabilitation (PR) are effective treatments for improving exercise capacity patient‐reported outcomes in patients severe Chronic Obstructive Pulmonary Disease (COPD). According to current recommendations, all BLVR‐EBV should have undergone PR first. Our aim was study the effects of both before after compared alone. Methods We included COPD who were eligible PR....
Background Bronchoscopic lung volume reduction using one-way endobronchial valves (BLVR-EBV) improves exercise capacity and quality of life in patients with severe emphysema. However, its effect on symptoms fatigue, anxiety depression is unclear. Furthermore, if the combination pulmonary rehabilitation (PR) BLVR-EBV yields additional impact these remains unknown. We hypothesized that would reduce PR lead to when compared alone. Methods The SoLVE study ( NCT03474471 ) was a prospective...
Introduction Patients with advanced emphysema eligible for bronchoscopic lung volume reduction (BLVR) using endobronchial valves (EBV) are characterized by severe static hyperinflation, which can be considered a treatable trait. Other traits (TTs), assumed to present in this highly selected patient group, have not been studied detail nor how they may affect health-related quality of life (HRQL). Aims We aimed evaluate spectrum TTs COPD patients EBV treatment and their association HRQL....
Abstract Background Various metrics of hospital antibiotic use might assist in guiding antimicrobial stewardship (AMS). Objectives To compare patient outcomes association with three methods to measure and feedback information on when used developing an AMS intervention. Methods Three were randomly allocated 42 clusters from 21 Dutch hospitals: (1) quantity [DDD, days-of-therapy (DOT) pharmacy data], versus (2) validated, or (3) non-validated quality indicators point prevalence studies. Using...
Abstract Pleural empyema is a severe condition associated with high morbidity and mortality. Treatment usually consists of pleural drainage chest tube or surgery, in combination antimicrobial treatment. Severe pneumonia can evolve necrotizing pneumonia, given higher susceptibility to the occurrence bronchopleural fistulas persistent air leaks. This complicates recovery, surgery may not always be optimal We present case involving 17‐year‐old female patient who experienced post‐operative leak...
To become a proactive and informed partner in postacute coronavirus disease 2019 (COVID-19) management, patients need to have the knowledge, skills, confidence self-manage COVID-19-related health challenges. Due several restrictions consequently social isolation, online platforms forums where people can share information experiences became more popular influential. Therefore, this study aimed identify perceived needs care of members 2 Facebook groups for with COVID-19 persistent complaints...
<b><i>Background:</i></b> Endoscopic lung volume reduction (ELVR) using one-way endobronchial valves is a technique to reduce hyperinflation in patients with severe emphysema by inducing collapse of severely destroyed pulmonary lobe. Patient selection mainly based on evaluation severity high-resolution computed tomography and perfusion scintigraphy. Dual-energy contrast-enhanced CT scans may be useful for assessment but has not been compared against...
Rationale: A significant reduction in hospitalizations for acute exacerbations of COPD (AECOPDs) has been reported during the coronavirus disease 2019 (COVID-19) pandemic. It remains unclear whether this is result health care avoidance by patients, or infection prevention and con
Bronchoscopic lung volume reduction (BLVR) using 1-way endobronchial valves (EBV) has become a guideline treatment in patients with advanced emphysema. Evidence from this minimally invasive derives mainly well-designed controlled trials conducted high-volume specialized intervention centres. Little is known about real-life outcome data hospitals setting up novel and which favourable conditions are required for continuous successful program.In study, we aim to evaluate the eligibility rate...
<title>Abstract</title> A significant proportion of COVID-19 survivors still experience a reduced diffusion capacity three and twelve months after discharge. We aimed to compare pulmonary function trajectories between hospitalized patients with pre-existing respiratory disease (PRD) without (Non-PRD) at hospital This single-centre retrospective cohort study included admitted the VieCuriMedical Centre (Venlo, Netherlands) February December 2020 that were invited outpatient clinic During this...