A5059244800- Anesthesia and Sedative Agents
- Airway Management and Intubation Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Pain Management
- Intensive Care Unit Cognitive Disorders
- Tracheal and airway disorders
- Anesthesia and Neurotoxicity Research
- Nausea and vomiting management
- Inflammatory mediators and NSAID effects
- Respiratory Support and Mechanisms
- Pain Mechanisms and Treatments
- Neuropeptides and Animal Physiology
- Intraoperative Neuromonitoring and Anesthetic Effects
- Congenital Heart Disease Studies
- Cardiac and Coronary Surgery Techniques
- Neonatal Respiratory Health Research
- Venous Thromboembolism Diagnosis and Management
- EEG and Brain-Computer Interfaces
- Cardiac Arrest and Resuscitation
- Potassium and Related Disorders
- Cardiac Valve Diseases and Treatments
- Atrial Fibrillation Management and Outcomes
- COVID-19 and healthcare impacts
- Biomedical and Chemical Research
- Pediatric Pain Management Techniques
Maastricht University
2009-2024
Maastricht University Medical Centre
2011-2024
Universitätsklinikum Würzburg
2017
University Medical Center
2009-2014
Saarland University
2001-2011
May Institute
2010
Centre Hospitalier Régional et Universitaire de Nancy
2009
Universitätsklinikum des Saarlandes
2002-2006
University of Rostock
2005
Université de Lorraine
2003
Background Vocal cord injuries, postoperative hoarseness, and sore throat are common complications after general anesthesia. One-lung ventilation can be achieved via two techniques: double-lumen endotracheal tube or endobronchial blocker such as the Arndt blocker. The current study was designed to assess impact of these techniques for one-lung on incidence severity vocal lesions, throat. Methods In this prospective trial, 60 patients were randomly assigned groups. with either an (blocker...
ANDEXANET ALFA (Ondexxya, Portola Pharmaceuticals, San Francisco, CA) is a modified recombinant inactivated human factor Xa. Although it currently only approved to reverse the effects of direct Xa (FXa) inhibitors, andexanet alfa initially was developed as reversal agent for and indirect FXa inhibitors.1 The acts decoy molecule that reversibly binds inhibitors consequently temporarily inhibits anticoagulant effects. In vitro studies showed binding affinity heparin-bound antithrombin...
In Brief Postoperative hoarseness (PH), sore throat (ST), and vocal cord injuries (VCI) are common complications after general anesthesia. Excellent endotracheal intubating conditions associated with less laryngeal morbidity than good or poor conditions. Thus, we tested the hypothesis that a rapid-sequence induction (RSI) succinylcholine would lead to PH VCI rocuronium. this prospective trial, 160 patients were randomized in 2 groups receive thiopental 5.0 mg/kg, fentanyl 3.0 μg/kg, 1.0...
Background: Acceleromyography has been shown to be an appropriate method in the detection of residual paralysis. However, clinical importance individual calibration device single patient improve reliability detecting paralysis remains unclear. Methods: Observational study 100 patients undergoing general anaesthesia with endotracheal intubation and a neuromuscular block atracurium. In all patients, individually calibrated acceleromyograph was used estimate possible at end surgery. Immediately...
This study was designed to investigate the impact of patient age on propofol consumption and recovery time using a propofol-remifentanil anaesthetic standardized with Narcotrend EEG monitoring. The is monitor for measuring depth anaesthesia based upon six-letter classification from A (awake) F (increasing burst suppression) including 14 substages.In 200 patients scheduled minor orthopaedic surgery electrodes were positioned patient's forehead as recommended by manufacturer. Anaesthesia...
Background: The purpose of this study was to investigate whether gender influences the perception pain on injection rocuronium. Methods: In prospective, placebo‐controlled trial 120 patients were randomized into four groups receive rocuronium 0.03 mg kg −1 (40 female and 40 male patients) or saline (20 20 patients). incidence severity after administration drug compared between using a numerical rating scale (0–10). Signs local irritation, i.e. erythema thrombophlebitis, assessed up 48 h...
Succinylcholine is a popular muscle relaxant for ambulatory anesthesia (1). Unfortunately, postoperative myalgia (POM) may frequently occur after the use of succinylcholine (2–7) and this be particularly troublesome in outpatients (3,5,6). Although pretreatment with nondepolarizing myorelaxants seems to effective decreasing fasciculation, its effectiveness reducing POM controversial (5,6). Moreover, produce weakness preceding loss consciousness (8). Interestingly, increasing evidence...
A common side effect associated with succinylcholine is postoperative myalgia. The pathogenesis of this myalgia still unclear; inflammation has been suggested but without convincing evidence. We designed the present study to investigate whether an inflammatory reaction contributes incidence and severity succinylcholine-associated was determined in 64 patients pretreated saline or dexamethasone before (n = 32 for each). Incidence did not differ significantly between two groups: 15 group...