A5006404288- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Cardiac and Coronary Surgery Techniques
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac Valve Diseases and Treatments
- Blood transfusion and management
- Venous Thromboembolism Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Airway Management and Intubation Techniques
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Infective Endocarditis Diagnosis and Management
- Congenital Heart Disease Studies
- Respiratory Support and Mechanisms
- Hemodynamic Monitoring and Therapy
- Heparin-Induced Thrombocytopenia and Thrombosis
- Anesthesia and Sedative Agents
- Cardiac Structural Anomalies and Repair
- Acute Myocardial Infarction Research
- Thermal Regulation in Medicine
- Trauma and Emergency Care Studies
- Cardiac Arrhythmias and Treatments
- Hemostasis and retained surgical items
- Cardiac pacing and defibrillation studies
University of Bern
2016-2025
University Hospital of Bern
2016-2025
Nuovo Ospedale San Giovanni di Dio
2024
Ospedale San Carlo
2024
Naples Anesthesia & Physician Associates
2024
Casa di Cura San Michele
2024
University of Campania "Luigi Vanvitelli"
2024
Duke University
2021
Heart and Diabetes Center North Rhine-Westphalia
2021
Ruhr University Bochum
2021
Transcatheter aortic valve implantation (TAVI) is an alternative to surgery for high-risk patients with severe stenosis. Periprocedural stroke reported at incidence up 10%. Magnetic resonance imaging studies have identified new onset of clinically silent ischaemic cerebral lesions more frequently (68-84%). So far, few data are available about embolism during TAVI. The aim this study was determine the frequency high-intensity transient signals (HITS) and explore differences in HITS pattern...
To date, data regarding the efficacy and safety of administering fibrinogen concentrate in cardiac surgery are limited. Studies limited by their low sample size large heterogeneity with regard to patient population, timing administration, definition transfusion trigger target levels. Assessment activity using viscoelastic point-of-care testing shortly before or after weaning from cardiopulmonary bypass patients procedures a high risk bleeding appears be rational strategy. In contrast, use...
Inherited and acquired coagulopathy are frequently associated with major bleeding in severe trauma, cardiac surgery cardiopulmonary bypass, postpartum hemorrhage. Perioperative management is multifactorial includes preoperative optimization discontinuation of anticoagulants antiplatelet therapy elective procedures. Prophylactic or therapeutic use antifibrinolytic agents strongly recommended guidelines has been shown to reduce need for allogeneic blood administration. In the context induced...
The goal of this study was to determine whether advanced age affects mortality and incidence neurological injury in patients undergoing surgical repair with hypothermic circulatory arrest acute chronic thoracic aortic pathology.A university center audit done 523 consecutive (median age, 64 years; interquartile range, 56-71 years) between 2005 2010. Mortality type A dissection (207 patients) 9.7%, ascending aneurysms (316 2.2% (P<0.001). Neurological observed 16.9% (chronic aneurysms, 7.9%;...
Endothelial glycocalyx participates in the maintenance of vascular integrity, and its perturbations cause capillary leakage, loss responsiveness, enhanced adhesion leukocytes platelets. We hypothesized that marked shedding core protein, syndecan-1, occurs end-stage liver disease (ESLD) it increases during orthotopic transplantation (OLT). further evaluated effects general anesthesia on association with acute kidney injury (AKI) after OLT.Thirty consecutive transplant recipients were enrolled...
Cyclic recruitment and derecruitment of atelectasis can occur during mechanical ventilation, especially in injured lungs. Experimentally, cyclic be quantified by respiration-dependent changes PaO2 (ΔPaO2), reflecting the varying intrapulmonary shunt fraction within respiratory cycle. This study investigated effect inspiration to expiration ratio upon ΔPaO2 Horowitz index.Prospective randomized study.Laboratory investigation.Piglets, average weight 30 ± 2 kg.At rate 6 breaths/min,...
Background The impact of hyperoxia, that is, supraphysiological arterial partial pressure O2, on myocardial oxygen balance and function in stable multivessel coronary artery disease (CAD) is poorly understood. In this observational study, we assessed effects inhalational hyperoxia patients with CAD using a comprehensive cardiovascular magnetic resonance exam. Methods Results Twenty-five underwent contrast-free exam the interval between their index angiography subsequent revascularization....
Noncardiac surgery after transcatheter aortic valve implantation (TAVI) is a clinical challenge with concerns about safety and optimal management.To evaluate perioperative risk of adverse events associated noncardiac TAVI by timing surgery, type performance.This cohort study was conducted using data from prospective registry patients at the tertiary care University Hospital in Bern, Switzerland. All undergoing were identified. Data analyzed November through December 2021.Timing, urgency,...