- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Blood transfusion and management
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Simulation-Based Education in Healthcare
- Venous Thromboembolism Diagnosis and Management
- Heparin-Induced Thrombocytopenia and Thrombosis
- Cardiac Ischemia and Reperfusion
- Atrial Fibrillation Management and Outcomes
- Cardiac Imaging and Diagnostics
- Nursing Roles and Practices
- Surgical Simulation and Training
- Advanced MRI Techniques and Applications
- Viral Infections and Immunology Research
- History of Medical Practice
- Helminth infection and control
- Ultrasound in Clinical Applications
- Parasitic Diseases Research and Treatment
- Cardiac pacing and defibrillation studies
- Human-Automation Interaction and Safety
- Orthopaedic implants and arthroplasty
Deutsches Herzzentrum der Charité
2005-2025
Berlin Heart (Germany)
2003-2022
Steinbeis University Berlin
2011-2020
Medtronic (Switzerland)
2004
Humboldt-Universität zu Berlin
2004
Heart and Diabetes Center North Rhine-Westphalia
2003
Martin Luther University Halle-Wittenberg
2003
Extracorporeal life support (ECLS) is one of the recent fields in cardiac surgery which has improved significantly quality patient care acute or chronic end-stage heart disease. The safe use this new technology requires many different prerequisites are summarized position article. It includes necessary personnel and their qualifications, structural assumptions, required equipment, parameters have to be monitored for usage these devices. In addition, indications contraindications ECLS,...
Disclaimer 2019: The EACTS/EACTA/EBCP Guidelines represent the views of EACTS, EACTA and EBCP were produced after careful consideration scientific medical knowledge evidence available at time their dating. are not responsible in event any contradiction, discrepancy and/or ambiguity between other official recommendations or guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies. Health professionals encouraged take fully into...
Mechanical cardiac assistance for neonates, infants, children and adolescents may be accomplished with pulsatile ventricular assist devices (VAD) instead of extracorporeal membrane oxygenation or centrifugal pumps. The Berlin Heart VAD consists extracorporeal, pneumatically driven blood pumps univentricular biventricular patients all age groups. are heparin-coated. stationary driving unit (IKUS) has the required enhanced compressor performance pediatric pump sizes. was used in a total number...
Cardiopulmonary bypass (CPB) in neonates and infants is associated with significant haemodilution when priming of the CPB circuit accomplished without transfusion homologous blood components. The degree and, thus, requirements for may be reduced miniaturized compromising patient safety.Between January 2002 October 2003, selected small were operated on using a nonhaemic prime extracorporeal circuit. volume could from 300 mL to 190 by dedicated neonatal console mast-mounted roller pump heads....
Recombinant hirudin (r-hirudin) is being used increasingly in patients with heparin-induced thrombocytopenia type II. Renal failure has been demonstrated to prolong the half-life of r-hirudin and cause bleeding who have undergone cardiopulmonary bypass (CPB). We assessed ability different filter systems for modified ultrafiltration eliminate vitro using simulated CPB. r-Hirudin concentration was measured (chromogenic laboratory standard plus ecarin clotting time) before after filtration, its...
The development of modern techniques in extracorporeal circulation is the result combined efforts physiologists, physicians, and engineers. Early experimental work at end 19th century was accomplished by such as von Schröder, Frey, Gruber, well Jacobj. These scientists laid foundation for three different artificial oxygenation devices isolated animal organ perfusion. developed bubble, film, lung methods were later used first clinical cardiopulmonary bypass procedures humans. For continuous...
Performing cardiac surgery on pediatric Jehovah's Witness patients is a great challenge for the surgical team and especially perfusionist. Witnesses reject blood transfusions grounds of their literal interpretation passages Bible. In accordance with this belief, feel that it also forbidden to retransfuse autologous has been separated from own circulatory system. We report use cardiopulmonary bypass (CPB) during open-heart in three infants body weight 4.5 kg, 3.5 3.1 respectively, without...
Background: Performing cardiopulmonary bypass is a complex task which involves evaluating visual input from patient monitors and technical parameters displayed at the heart-lung machine console as well reacting to other sensory input. Only few studies are available concerning competency requirements for clinical cardiovascular perfusionists, including attention, perception, coping with mental stress. This study aims stress levels of perfusionists during bypass. Methods: Nine voluntarily...
The first roller pump was patented in 1855 by Porter and Bradley hand operated. A modification named "surgical pump", designed manufactured E. Allen 1887, intended for direct blood transfusion. Truax, who also distributed promoted the with one roller, developed double 1899. In following decades, several researchers, including Beck, Van Allen, Bayliss Müller as well Henry Jouvelet, refined apparatus recommended use of pumps transfusion other applications. After further modifications made...
In Brief Cardiac surgery involving cardiopulmonary bypass (CPB) leads to activation of the hemostatic/inflammatory system. We compared influence a half-dose aprotinin regimen on postoperative blood loss and system during CPB, when used heparin-level-based heparin management for cardiac surgery. Two-hundred patients (n = 100 in each group) were enrolled this randomized prospective study. Group I only was given according results Hepcon HMS Plus™. II added with bolus 1 × 106 kallikrein...
Perfusion education and training varies considerably throughout Europe. Unlike in the US, where a common curriculum for perfusion has been established, each European country its own system. This fact is further complicated by multitude of national languages cultures. Thus, programmes vary, not only content, but also their academic levels. article aims to give comprehensive overview situation 20 member states Board Cardiovascular (EBCP). The EBCP delegates were polled description process...
The short-acting platelet glycoprotein IIb/IIIa antagonist tirofiban is beneficial when used in the context of cardiac surgery. Tirofiban has an elimination half-life 2 h. Renal failure prolongs and continues inhibition aggregation refractory to transfusions platelets. Extracorporeal necessary prevent excessive hemorrhage this condition. We assessed by hemofiltration vitro model cardiopulmonary bypass (CPB). Two hemofilters one plasmapheresis filter were assessed. Three separate filters each...
Objectives: Evaluation of critical events training for clinical perfusionists is necessary to improve this educational approach. Critical checklists are effective in reducing complications, but should be tested a simulation environment first. Individual behavior and stress response during simulated on cardiopulmonary bypass have not been evaluated yet. This study focuses the evaluation bypass. Methods: A total 19 from single hospital took part two event scenarios. Clinical perfusionist...