- MRI in cancer diagnosis
- Blood Pressure and Hypertension Studies
- Cardiac Imaging and Diagnostics
- Renal and Vascular Pathologies
- Chronic Kidney Disease and Diabetes
- Heart Rate Variability and Autonomic Control
- Advanced MRI Techniques and Applications
- Heart Failure Treatment and Management
- Cardiac Health and Mental Health
- Attention Deficit Hyperactivity Disorder
- Acute Myocardial Infarction Research
- Child and Adolescent Psychosocial and Emotional Development
- COVID-19 Clinical Research Studies
- RNA regulation and disease
- Health and Well-being Studies
- Diabetes Treatment and Management
- Long-Term Effects of COVID-19
- Chemotherapy-related skin toxicity
- Chronic Disease Management Strategies
- Linguistic Variation and Morphology
- Infant Development and Preterm Care
- Aging, Health, and Disability
- Genital Health and Disease
- Mechanical Circulatory Support Devices
- Cardiovascular Health and Disease Prevention
Royal Devon & Exeter NHS Foundation Trust
2017-2024
Royal Devon and Exeter Hospital
2017-2024
NIHR Exeter Clinical Research Facility
2019-2024
University of Exeter
2020-2024
University of Suffolk
2023
Sleep Management Institute
2017
University of Wales
2000-2002
St Cadoc's Hospital
2001
Atkins (United Kingdom)
2001
Memorial Hospital
1997
Patients with cardiac disease are considered high risk for poor outcomes following hospitalization COVID-19. The primary aim of this study was to evaluate heterogeneity in associations between various heart subtypes and in-hospital mortality.
Diabetic kidney disease (DKD) remains one of the leading causes premature death in diabetes. DKD is classified on albuminuria and reduced function (estimated glomerular filtration rate (eGFR)) but these have modest value for predicting future renal status. There an unmet need biomarkers that can be used clinical settings which also improve prediction decline top routinely available data, particularly early stages. The iBEAt study BEAt-DKD project aims to determine whether imaging (magnetic...
Aims and Method General practitioners (GPs) were surveyed on their experience of attitudes towards attention-deficit hyperactivity disorder (ADHD) treatment using methylphenidate, asked about prescribing practice. Results Most GPs have children with ADHD the use methylphenidate. The majority felt that it was a drug should be initiated by specialist who continue to provide clinical monitoring, but primary care could ongoing physical monitoring. There lack training in this area, most...
Abstract Aims/hypothesis Although cardiovascular disease is the biggest cause of death in people with diabetes, microvascular complications have a significant impact on quality life and financial burden disease. Little known about progression dysfunction early stages type 2 diabetes before occurrence clinically apparent complications. We aimed to explore determinants endothelial-dependent -independent function over 3 year period, without both few clinical Methods Demographics were collected...
Abstract Aims Patients with cardiac disease are considered high risk for poor outcomes following hospitalization COVID-19. The primary aim of this study was to evaluate heterogeneity in associations between various heart subtypes and in-hospital mortality. Method results We used data from the CAPACITY-COVID registry LEOSS study. Multivariable Poisson regression models were fitted assess association different types pre-existent 16,511 patients COVID-19 included (21.1% aged 66 – 75 years;...
Left ventricular (LV) hypertrophy (LVH) in uncontrolled hypertension is an independent predictor of mortality, though its regression with treatment improves outcomes. Retrospective data suggest that early control provides a prognostic advantage and this strategy included the 2018 European guidelines, which recommend treating grade II/III to target blood pressure (BP) within 3 months. The earliest LVH date was demonstrated by echocardiography at 24 weeks. effect rapid guideline-based protocol...
ABSTRACT Diabetic kidney disease (DKD) is traditionally classified based on albuminuria and reduced function (estimated glomerular filtration rate (eGFR)), but these have limitations as prognostic biomarkers due to the heterogeneity of DKD. Novel markers are needed improve stratification patients risk progression. The iBEAT study, part BEAt-DKD consortium, aims determine whether renal imaging (magnetic resonance (MRI) ultrasound (US)) provide insight into pathogenesis DKD (primary aim), they...
Abstract Background Coronary microvascular disease is often defined by symptoms in the absence of epicardial coronary artery stenosis. There is, however, a growing interest exploring vascular physiology patients with chest pain syndromes who have been confirmed to unobstructed arteries. As it known that people an additive poor prognosis, we aimed determine whether this was part systemic dysregulation. such, explored correlations between cardiovascular magnetic resonance (CMR) myocardial...
Objective: There is growing evidence to suggest that timing of BP control in subjects with hypertension influences future risk cardiovascular events. The safety and feasibility delivering an accelerated treatment programme rapidly newly-diagnosed unknown. We sought determine whether patients moderate-severe could be effectively safely treated target by 18 weeks. Design method: Patients aged 18–79 years never-treated grade II-III were recruited following a usual care office systolic >170 mmHg...
Hypertension is a highly prevalent condition, with optimal treatment to BP targets conferring significant gains in terms of cardiovascular outcomes. Understanding why some patients do not achieve would be enhanced through greater understanding their health-related quality life (HRQoL). However, the only English language disease-specific instruments for measurement HRQoL hypertension have been validated accordance accepted standards. It proposed that Spanish MINICHAL instrument assessment...
Abstract Background: Hypertension is a highly prevalent condition, with optimal treatment to BP targets conferring significant gains in terms of cardiovascular outcomes. Understanding why some patients do not achieve would be enhanced through greater understanding their health-related quality life (HRQoL). However, the only English language disease-specific instruments for measurement HRQoL hypertension have been validated accordance accepted standards. It proposed that Spanish MINICHAL...
Objective: Inter-arm differences (IAD) in systolic blood pressure (SBP) predict future cardiovascular mortality and morbidity. IAD varies between measures gets smaller with repeated measures. The relationship of to response antihypertensive treatment is unknown. We set out examine associations BP over 18 weeks treatment-naïve adults moderate severe hypertension. Design method: previously reported that nurse-led accelerated stepwise management grade II/III hypertension feasible, safe...
Abstract There is limited empirical research and insight into the experiences of therapy trainees who are being taught more than one psychotherapeutic approach during their training. Further understanding warranted to ensure that a dual modality training (that is, where therapists trained in two paradigmatically distinct modalities) experienced as worthwhile acceptable better understand any challenges faced when transitioning between approaches. The aim this study was investigate trainees'...
Mothers of newborn babies have an average 4 hours' sleep a night and if young child is proving resistant to routine, the terror tiredness continues. Here's how establish-and maintain-a technique that will benefit all.
The non-governmental Foundation for Integrated Assistance to the Elderly and Family (FAIAF) in Argentina provides technical support teams which enable groups of elderly people develop artistic, cultural, educational productive activities; a principal objective is independent functioning groups. method intervention described, results an initial evaluation given.