A5085367208- Diet and metabolism studies
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Bone health and osteoporosis research
- Liver Disease Diagnosis and Treatment
- Nutrition and Health in Aging
- Bariatric Surgery and Outcomes
- Bone health and treatments
- Vitamin D Research Studies
- Adipose Tissue and Metabolism
- Renal Transplantation Outcomes and Treatments
- Muscle metabolism and nutrition
- Diabetes Management and Research
- Obesity and Health Practices
- Respiratory Support and Mechanisms
- Adipokines, Inflammation, and Metabolic Diseases
- Eating Disorders and Behaviors
- Diet, Metabolism, and Disease
- Diabetes Treatment and Management
- Metabolism and Genetic Disorders
- Body Contouring and Surgery
- Intensive Care Unit Cognitive Disorders
- Diabetes and associated disorders
- Liver Disease and Transplantation
- Metabolism, Diabetes, and Cancer
Istituti di Ricovero e Cura a Carattere Scientifico
2018-2025
MultiMedica
2021-2025
San Raffaele University of Rome
2020-2025
Italian Society of Physiotherapy
2023
Vita-Salute San Raffaele University
2018-2022
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2018-2022
Università Cattolica del Sacro Cuore
2015-2022
Agostino Gemelli University Polyclinic
2015-2022
The Open University
2022
Mylan (South Africa)
2021
Bariatric surgery in obese patients is a highly effective method of preventing or resolving type 2 diabetes mellitus (T2DM); however, the remission rate not same among different surgical procedures. We compared effects 20% weight loss induced by laparoscopic adjustable gastric banding (LAGB) Roux-en-Y bypass (RYGB) on metabolic response to mixed meal, insulin sensitivity, and β cell function nondiabetic adults. The meal ingestion was markedly after RYGB than LAGB surgery, manifested rapid...
Background & aimsCoronavirus disease 2019 (COVID-19) may associate with clinical manifestations, ranging from alterations in smell and taste to severe respiratory distress requiring intensive care, that might weight loss malnutrition. We aimed assess the incidence of unintentional malnutrition COVID-19 survivors.MethodsIn this post-hoc analysis a prospective observational cohort study, we enrolled all adult (age ≥18 years) patients confirmed diagnosis who had been discharged home either...
Data on residual clinical damage after Coronavirus disease-2019 (COVID-19) are lacking. The aims of this study were to investigate whether COVID-19 leaves behind dysfunction, and identify patients who might benefit from post-discharge monitoring. All aged ≥18 years admitted the Emergency Department (ED) for COVID-19, evaluated at follow-up between 7 April May, 2020, enrolled. Primary outcome was need follow-up, defined as presence least one among: respiratory rate (RR) >20 breaths/min,...
This Viewpoint explores the effects of weight loss achieved through GLP-1–based antiobesity medications on regain, fat-free mass, and skeletal muscle mass in people with obesity.
ABSTRACT Increased circulating sclerostin and accumulation of advanced glycation end-products (AGEs) are two potential mechanisms underlying low bone turnover increased fracture risk in type 2 diabetes (T2D). Whether the expression sclerostin-encoding SOST gene is altered T2D, whether it associated with AGEs or regulation other formation-related genes unknown. We hypothesized that accumulate upregulated bones from subjects leading to downregulation forming (RUNX2 osteocalcin) impaired...
Obese subjects with coronavirus disease 2019 (COVID-19) are at increased risk of requiring critical care (1), suggesting that excess body fat associates greater severity. BMI does not discriminate between and lean mass poorly reflects distribution. Cardiometabolic diseases systemic inflammation, two conditions associated visceral adiposity, also linked to COVID-19 severity fatality (1,2). The aim this study was assess the relationship abdominal distribution We hypothesized adipose tissue...
Background: There is no information on acute kidney injury (AKI) and continuous renal replacement therapy (CRRT) among invasively ventilated coronavirus disease 2019 (COVID-19) patients in Western healthcare systems. Objective: To study the prevalence, characteristics, risk factors outcome of AKI CRRT COVID-19 patients. Methods: Observational a tertiary care hospital Milan, Italy. Results: Among 99 patients, 72 (75.0%) developed 17 (17.7%) received CRRT. Most stage 1 (33 [45.8%]), while 15...
Adults with type 2 diabetes (T2D) have higher fracture risk compared nondiabetics, despite having bone mineral density (BMD). Insulin resistance (IR) has been associated increased BMD. It is not known if IR increases risk. We investigated the relationship among HOMA-IR, BMD, and incident nonspine fractures in nondiabetic individuals. Participants included 2398 community-dwelling, older adults (age 74 ± 3 years, 53% women, 38% black) Health, Aging Body Composition Prospective Cohort Study...
Abstract Background Host inflammation contributes to determine whether SARS-CoV-2 infection causes mild or life-threatening disease. Tools are needed for early risk assessment. Methods We studied in 111 COVID-19 patients prospectively followed at a single reference Hospital fifty-three potential biomarkers including alarmins, cytokines, adipocytokines and growth factors, humoral innate immune neuroendocrine molecules regulators of iron metabolism. Biomarkers hospital admission together with...
To provide a comprehensive assessment of multiorgan insulin sensitivity in lean and obese subjects with normal glucose tolerance.The hyperinsulinemic-euglycemic clamp procedure stable isotopically labeled tracer infusions was performed 40 (BMI 36.2 ± 0.6 kg/m(2), mean SEM) 26 (22.5 0.3 kg/m(2)) tolerance. Insulin infused at different rates to achieve low, medium, high physiological plasma concentrations.In subjects, palmitate R(a) decreased increasing concentrations. The decrease endogenous...