- Cardiac, Anesthesia and Surgical Outcomes
- Pain Management and Opioid Use
- Nosocomial Infections in ICU
- Sepsis Diagnosis and Treatment
- Pain Mechanisms and Treatments
- Cardiac Arrest and Resuscitation
- Hemodynamic Monitoring and Therapy
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Anesthesia and Pain Management
- Stroke Rehabilitation and Recovery
- Renal function and acid-base balance
- Cardiac Valve Diseases and Treatments
- Intensive Care Unit Cognitive Disorders
- Family and Patient Care in Intensive Care Units
- Physical Activity and Health
- Cardiac Ischemia and Reperfusion
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Musculoskeletal pain and rehabilitation
- Anesthesia and Neurotoxicity Research
- Pediatric Pain Management Techniques
- Antimicrobial Resistance in Staphylococcus
- Antibiotic Use and Resistance
- Nausea and vomiting management
- Blood Pressure and Hypertension Studies
- Cardiovascular Function and Risk Factors
University of Cagliari
2015-2025
Azienda Ospedaliero-Universitaria Cagliari
2008-2023
Azienda Ospedaliero Universitaria San Giovanni Battista
2016
University of Turin
2016
Intensive Care Society
2015
Meropenem is a widely prescribed β-lactam antibiotic. exhibits maximum pharmacodynamic efficacy when given by continuous infusion to deliver constant drug levels above the minimal inhibitory concentration. Compared with intermittent administration, administration of meropenem may improve clinical outcomes.To determine whether reduces composite mortality and emergence pandrug-resistant or extensively drug-resistant bacteria compared in critically ill patients sepsis.A double-blind, randomized...
In patients undergoing cardiac surgery, a reduced preoperative left ventricular ejection fraction (LVEF) is common and associated with worse outcome. Available outcome data for these address specific surgical procedures, mainly coronary artery bypass graft (CABG). Aim of our study was to investigate perioperative surgery on low pre-operative LVEF broad range procedures. Data from ≤40 % at university hospital were reviewed analyzed. A subgroup analysis ≤30 also performed. total 7313 underwent...
Objectives: We aimed to identify all treatments that affect mortality in adult critically ill patients multicenter randomized controlled trials. also evaluated the methodological aspects of these studies, and we surveyed clinicians' opinion usual practice for selected interventions. Data Sources: MEDLINE/PubMed, Scopus, Embase were searched. Further articles suggested inclusion from experts cross-check references. Study Selection: fulfilled following criteria: publication a peer-reviewed...
Physical activity in the elderly is recommended by international guidelines to protect against cognitive decline and functional impairment.This Randomized Controlled Trial (RCT) was set up verify whether medium-intensity physical people living community effective improving performance.RCT with parallel balanced large groups.Academic university hospital Olympic gyms.People aged 65 years old older of both genders at home holding a medical certificate for suitability non-competitive...
Aim: Pain represents the most frequent cause for patient admission to emergency departments (EDs). Oligoanalgesia is a common problem in this field. The aims of study were assess prevalence and intensity pain patients who visited second-level urban ED evaluate efficacy pharmacological treatment administered subsequent variations intensity. Methods: A 4-week prospective observational was carried out on 2,838 ED. evaluated using Numeric Rating Scale at moment triage. prescribed analgesic...
Abstract Background Aging is marked by a progressive rise in chronic diseases with an impact on social and healthcare costs. Physical activity (PA) may soothe the inconveniences related to diseases, has positive effects quality of life biological rhythms, can prevent decline motor functions consequent falls, which are associated early death disability older adults. Methods We randomized 120 over-65 males females into groups similar size timing will give each either moderate physical or...
To compare the six-month outcome on mood, cognition and quality of life (QoL) in patients with severe carotid atherosclerosis (CA) who underwent endarterectomy (CEA) subjects refused treatment.Cohort study consecutive inpatients CA (stenosis ≥ 50 %) (N = 46; age 72.56 ± 7.26; male 65.2 %). Intervention cohort: decided to undergo CEA 35); Control cohort 11). DSM-IV-Psychiatric diagnosis made by clinicians using interviews, QoL measured Short Form Health Survey (SF-12); cognitive performance...
The elderly undergo cardiac surgery more and frequently, often present multiple comorbidities, assume chronic therapies, a unique physiology. Aim of our study was to analyze the experience referral center with all types interventions performed in patients ≥80 years old over six years' period. A retrospective observational university hospital. 260 were included (3.5% undergoing period). Mean age 82 ± 1.8 years. Eighty-five percent underwent elective surgery, 15% unplanned 4.2% redo surgery....
The diagnosis of pain nature is a troublesome task and wrong attribution often leads to an increase costs avoidable pharmaceutical adverse reactions. An objective specific approach achieve this highly desirable. aim work was investigate urine samples collected from patients suffering different by metabolomics based on (1)H NMR spectroscopy multivariate statistical analysis. We performed prospective study 74 subjects: 37 (12 with nociceptive 25 neuropathic pain), controls not any kind chronic...
This study aimed to verify, through a randomized controlled trial, whether medium-intensity mixing/aerobic/anaerobic exercise (accessible older adults even with mild chronic diseases) can effectively counteract depressive episodes. A characteristic of the trial was that follow-up coincided (unscheduled) lockdown due Covid-19.Participants (N=120) were into an intervention group, performing physical exercise, and control group. Participants, aged 65 years older, belonged both genders, living...