- Anesthesia and Pain Management
- Pain Management and Opioid Use
- Musculoskeletal pain and rehabilitation
- Pain Mechanisms and Treatments
- Pediatric Pain Management Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Nausea and vomiting management
- Spine and Intervertebral Disc Pathology
- Airway Management and Intubation Techniques
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Cardiac Arrest and Resuscitation
- Anesthesia and Sedative Agents
- Myofascial pain diagnosis and treatment
- Palliative Care and End-of-Life Issues
- Shoulder Injury and Treatment
- Opioid Use Disorder Treatment
- Tracheal and airway disorders
- COVID-19 Clinical Research Studies
- Gastrointestinal motility and disorders
- Trauma Management and Diagnosis
- Disaster Response and Management
- Gastroesophageal reflux and treatments
- Intensive Care Unit Cognitive Disorders
- SARS-CoV-2 and COVID-19 Research
- Pharmacological Effects and Toxicity Studies
University of L'Aquila
2016-2025
San Salvatore Hospital
2017-2024
Istituto Superiore di Sanità
2023
University of Padua
2023
University of Siena
2023
Agenzia Sanitaria Regionale Abruzzo
2023
University of Teramo
2014-2021
Fondazione Roma
2012
Italian Association for Cancer Research
2012
Università Campus Bio-Medico
1999-2000
Efficacy of epidural local anesthetics plus steroids for the treatment cervicobrachial pain is uncertain.A prospective study randomized 160 patients with resistant to conventional therapy. Patients were divided into 4 groups on basis time between onset and initiation: group A, 40 15 30 days; B, from 31 60 C, patients, 61 180 D, >180 days. each receive an block bupivacaine methylprednisolone at intervals 5 days (Single injection) or continuous every 6, 12, 24 hours (Continuos epidural). The...
Tailoring effective strategies for cancer pain management requires a careful analysis of multiple factors that influence phenomena and, ultimately, guide the therapy. While there is wealth research on automatic assessment (APA), its integration with clinical data remains inadequately explored. This study aimed to address potential correlations between subjective and APA-derived objectives variables in cohort patients. A multidimensional statistical approach was employed. Demographic,...
The treatment of acute pain in the prehospital emergency setting remains a significant problem. We evaluated incidence, site, and possible cause period also current state management by evaluating analgesic availability vehicles Italy.First aid volunteers documented presence, intensity, site questionnaire for over 3 months. Emergency service operations completed on ambulances helicopters.Pain symptoms were present two-thirds patients (n = 383) ranked as moderate to unbearable 41.75%. Results...
Abstract Introduction On 6 April 2009, at 03:32 local time, an Mw 6.3 earthquake hit the Abruzzi region of central Italy causing widespread damage in City L Aquila and its nearby villages. The caused 308 casualties over 1,500 injuries, displaced more than 25,000 people induced significant to 10,000 buildings L'Aquila region. Objectives This observational retrospective study evaluated prevalence drug treatment pain five weeks following (April 6, 2009). Methods 958 triage documents were...
Aim: Pain represents the most frequent cause for patient admission to emergency departments (EDs). Oligoanalgesia is a common problem in this field. The aims of study were assess prevalence and intensity pain patients who visited second-level urban ED evaluate efficacy pharmacological treatment administered subsequent variations intensity. Methods: A 4-week prospective observational was carried out on 2,838 ED. evaluated using Numeric Rating Scale at moment triage. prescribed analgesic...
At the end of 2019, Health Committee Wuhan alerted World Organization (WHO) about a cluster patients with pneumonia unknown etiology.1 The etiology turned out to be novel variant Coronaviridae family viruses, which includes viruses responsible for severe acute respiratory syndrome (SARS) and Middle East (MERS). Because this new coronavirus (CoV) genetically approximates virus SARS outbreak (severe [SARS-CoV]), International on Taxonomy Viruses termed 2 (SARS-CoV-2) its associated human...
Current available therapeutic options for Coronavirus Disease-2019 (COVID-19) are primarily focused on treating hospitalized patients, and there is a lack of oral to treat mild moderate outpatient COVID-19 prevent clinical progression. Raloxifene was found as promising molecule due its activity modulate the replication severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) act an immunomodulator decrease proinflammatory cytokines.This phase 2 multicenter, randomized, placebo-controlled...
ABSTRACT Background Cancellation of pediatric day and ambulatory surgeries on the procedure poses a significant challenge, impacting hospital resources patient care. In Italy, surgery is defined as surgical/diagnostic without hospitalization, with daytime hospitalization. Aims To measure rate causes cancellations in tertiary Italy. Methods We collected data retrospectively from electronic health record between January 2020 March 2022 at Ospedale Pediatrico Bambino Gesù Rome, The number case...
We assessed the relative morphine consumption in a combined analgesic regimen (on-demand plus nonopioids propacetamol or ketorolac) after gynecologic surgery. Two hundred women randomly received two IV doses of 2 g ketorolac 30 mg double-blinded, double-dummy trial. Patients were monitored for 12 h, and following efficacy variables assessed; total dose morphine, pain intensity, global efficacy. Safety tolerability evaluated by occurrence adverse events, especially presence intensity...
The aim of this double‐blind randomized study was to evaluate the optimal intravenous dose Clonidine administrated during peri‐operative period, after lumbar hemilaminectomy for herniated disk repair. ‘optimal dose’ defined as that providing minimal analgesic request, stable haemodynamic profile and a sedation score 12 h extubation. Eighty adult patients, ASA physical status I–II, undergoing (L 4 ‐L 5 , L ‐S 1 ) were included in study. All patients randomly assigned one four groups (A, B, C,...
BackgroundAlthough preventive strategies have been proposed against catheter-associated urinary tract infections (CAUTIs) in intensive care units (ICUs), more efforts are needed to control the incidence rate.AimTo distinguish patients according their characteristics at ICU admission, and identify clusters of higher risk for CAUTIs.MethodsA two-step cluster analysis was conducted on 9656 from Italian Nosocomial Infections Surveillance Intensive Care Units project.FindingsThree were...
Abstract Background In 2016, we performed a one-day investigation to analyze the prevalence of pain, pain intensity, and therapy in Departments Surgery Onco-Hematology Ospedale Pediatrico Bambino Gesù. To improve knowledge gap highlighted previous study, refresher courses even personalized audits have been carried out during these years. The purpose this study is evaluate if, after 5 years, there improvements management pain. Methods was conducted on 25 January 2020. Pain assessment,...
We assessed the relative morphine consumption in a combined analgesic regimen (on-demand plus nonopioids propacetamol or ketorolac) after gynecologic surgery. Two hundred women randomly received two IV doses of 2 g ketorolac 30 mg double-blinded, double-dummy trial. Patients were monitored for 12 h, and following efficacy variables assessed; total dose morphine, pain intensity, global efficacy. Safety tolerability evaluated by occurrence adverse events, especially presence intensity...