- Pain Management and Opioid Use
- Palliative Care and End-of-Life Issues
- Pediatric Pain Management Techniques
- Cancer survivorship and care
- Pharmacological Effects and Toxicity Studies
- Childhood Cancer Survivors' Quality of Life
- Pain Mechanisms and Treatments
- Anesthesia and Pain Management
- Intensive Care Unit Cognitive Disorders
- Cancer Diagnosis and Treatment
- Oral health in cancer treatment
- Management of metastatic bone disease
- Patient Dignity and Privacy
- Opioid Use Disorder Treatment
- Nausea and vomiting management
- Pain Management and Placebo Effect
- Sleep and related disorders
- Head and Neck Cancer Studies
- Pathogenesis and Treatment of Hiccups
- Frailty in Older Adults
- Family and Patient Care in Intensive Care Units
- Grief, Bereavement, and Mental Health
- Restless Legs Syndrome Research
- Gastroesophageal reflux and treatments
- Sympathectomy and Hyperhidrosis Treatments
University of Teramo
2019-2022
Ospedale San Giuseppe
2019-2021
University of L'Aquila
2011-2020
IRCCS Policlinico San Donato
2020
Ca' Foncello Hospital
2015
San Salvatore Hospital
2010-2014
La Maddalena
2006-2010
University of Palermo
2006-2008
Pain is common in cancer patients, particularly the advanced stage of disease when prevalence estimated to be more than 70% [1.Portenoy R.K. Treatment pain.Lancet. 2011; 377: 2236-2247Abstract Full Text PDF PubMed Scopus (308) Google Scholar], contributing poor physical and emotional well-being. The most comprehensive systematic review indicates pain ranging from 33% patients after curative treatment, 59% on anticancer treatment 64% with metastatic, or terminal [2.van den Beuken-van...
The aim of this study was to compare the analgesic and adverse effects, doses, as well cost opioid drugs, supportive drug therapy other drugs in patients treated with oral sustained-release morphine, transdermal fentanyl, methadone.One hundred eight cancer patients, no longer responsive opioids for moderate pain, were selected randomly receive initial daily doses 60 mg 15 methadone, or 0.6 (25 microg/h) fentanyl. Oral morphine used breakthrough pain medication during titration. Opioid...
An important goal for cancer patients is to improve the quality of life (QOL) by maximising functions affected disease and its therapy. Preliminary research suggests that exercise may be an effective intervention enhancing QOL in survivors. Research has provided preliminary evidence safety, feasibility, efficacy training breast The aim this study was assess association between physical a population female survivors, followed up from diagnosis off-treatment time period, investigated about...
The aim of this prospective, open-label study was to evaluate the efficacy and tolerability tapentadol (TP) in management cancer pain.A 4 weeks' prospective carried out 50 opioid-naive patients with moderate-severe pain. Each patient initially received twice-daily doses slow-release TP mg. Doses were then managed maintain adequate relief or dose-limiting toxicity, on basis clinical response. following parameters recorded at weekly intervals for weeks: pain opioid-related adverse effects,...
Background: The aim of this study was to identify potential variables influencing the clinical presentation breakthrough cancer pain (BTP). Methods: Cancer patients with a diagnosis BTP were enrolled. Demographic and characteristics, as well background characteristics collected. Multivariate analyses conducted assess correlation between examined. Results: Data 4016 analysed. Average daily number episodes 2.4, mean intensity 7.5, duration 43.3 min. A short onset observed in 68.9% patients. In...
To evaluate safety and efficacy of gabapentin in the treatment severe chronic hiccups patients with advanced cancer.Charts all observed palliative care unit a 4-bed hospital at home by our Home Care Service were reviewed retrospectively.The presence was routinely assessed. Patients treated (300 mg t.i.d.). Doses titrated based on response to treatment.Gabapentin-related adverse effects recorded.Thirty-seven (3.9%) 944 in-hospital 6 (4.5%) 134 presented hiccups.We registered an improvement...
Objectives:The aim of this study was to compare the efficacy and safety doses fentanyl buccal tablet (FBT) proportional opioids used for background analgesia versus dose titration starting with minimal management breakthrough cancer pain (BTcP).Methods:A total 82 patients BTcP who were receiving strong in at least 60 mg oral morphine equivalents having acceptable analgesia, selected a multicenter unblinded study. Forty-one randomized receive FBT daily opioid four consecutive episodes (group...
The aim of this exploratory study was to assess the conversion ratios between tapentadol and other opioids in patients requiring an opioid switching.A prospective carried out a convenience sample consecutive admitted acute palliative care unit home for period 1 year. Patients who were switched from/to selected. initial ratio opioids, expressed as oral morphine equivalents 1:3.3. subsequent doses flexible changed fit patients' needs. Pain intensity distress score recorded until stable. In...