A5083175502- Pain Management and Treatment
- Pain Mechanisms and Treatments
- Pain Management and Opioid Use
- Musculoskeletal pain and rehabilitation
- Helicobacter pylori-related gastroenterology studies
- Spine and Intervertebral Disc Pathology
- Anesthesia and Pain Management
- Eosinophilic Esophagitis
- Pharmacological Effects and Toxicity Studies
- Peripheral Nerve Disorders
- Central Venous Catheters and Hemodialysis
- Transcranial Magnetic Stimulation Studies
- COVID-19 Clinical Research Studies
- Streptococcal Infections and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Dermatological and COVID-19 studies
- Shoulder Injury and Treatment
- Pediatric Pain Management Techniques
- Gastric Cancer Management and Outcomes
- Long-Term Effects of COVID-19
- Opioid Use Disorder Treatment
- Lymphoma Diagnosis and Treatment
- Oral health in cancer treatment
- Herbal Medicine Research Studies
- Music Therapy and Health
Ospedale Monaldi
2016-2025
Azienda Sanitaria Locale Roma 3
2021
Marche Polytechnic University
2017
University of Rome Tor Vergata
2015
Objective: A survey of breakthrough pain (BTP) was performed in five palliative care units (PCU), seven oncology departments (ONC), and nine clinics (OPC). Methods: standard algorithm used to confirm the diagnosis BTP patients refereed different settings. Results: 1,412 evaluable cancer were enrolled. 53.9% males mean age 63.7±13.1 years. The intensity background 2.8±0.73. Patients reported 2.4±1.1 episodes/day with a 7.37±1.28. 80.6% that had significant negative impact everyday life....
Background: The aim of this study was to identify potential variables influencing the clinical presentation breakthrough cancer pain (BTP). Methods: Cancer patients with a diagnosis BTP were enrolled. Demographic and characteristics, as well background characteristics collected. Multivariate analyses conducted assess correlation between examined. Results: Data 4016 analysed. Average daily number episodes 2.4, mean intensity 7.5, duration 43.3 min. A short onset observed in 68.9% patients. In...
Abstract The prevalence of chronic pain is between 33% to 64% and due cancer pain, but it has also been observed in non-cancer patients. Chronic associated with lower quality life higher psychological distress depressive/anxiety disorders patients without a history disorder. In this study we evaluated clinical practice the effectiveness intrathecal pump 140 who underwent therapy at our Center. These were consecutively enrolled from January 2010 July 2018. Follow-up was carried out over these...
Abstract Retroperitoneal fibrosis is a connective disease of the auto-inflammatory/auto-immune type retroperitoneum with unknown etiology and pathological mechanism. The manifestations pathology can be local or systemic. Amongst symptoms, dull constant pain in hips, back abdomen most frequent. We report here case 47-year-old woman, whose pathogenic mechanism could related to an “IgG4-related disease” disorder as suggested by increased serum level this subclass IgG positive...
Administration of rituximab, one the basic drugs for therapy B-cell lymphoproliferative diseases, during pregnancy has been suspected to cause developmental fetal events, particularly if given first trimester pregnancy. Therefore, use in is not permitted. Howe ver, several cases pregnant women being treated with rituximab are reported herein; an exception often made grave illness. We describe exceptional case a woman non-Hodgkin lymphoma mucosa-associated lymphoid tissue type where was as...
An ongoing national multicenter survey [Italian Oncologic Pain multiSetting Multicentric Survey (IOPS-MS)] is evaluating the characteristics of breakthrough cancer pain (BTP) in different clinical settings. Preliminary data from first 1500 patients with BTP enrolled this study are presented here. Thirty-two centers involved survey. A diagnosis was performed by a standard algorithm. Epidemiological data, Karnofsky index, stage disease, presence and sites metastases, oncologic treatment,...
PURPOSE A large proportion of patients with cancer suffer from breakthrough pain (BTcP). Several unmet clinical needs concerning BTcP treatment, such as optimal opioid dosages, are being investigated. In this analysis the hypothesis, we explore an unsupervised learning algorithm whether distinct subtypes exist and they can provide new insights into practice. METHODS Partitioning around a k-medoids on data set BTcP, previously collected by Italian Oncologic Pain Survey group, was used to...
Background: A variety of skin manifestations have been associated with COVID-19 infection. Acral lesions on hands and feet, closely resembling chilblains, reported in association COVID-19, which are nonspecific. These acro-ischemic painful described mainly asymptomatic mildly symptomatic pediatric positive patients, without a precise pathogenetic mechanism.COVID-19-induced chilblains may portend an indolent course good outcome. In young the IFN-1 response induces microangiopathic changes...
Face masks during COVID-19 pandemic lockdown and self-reported seasonal allergic rhinitis symptoms
Over the last 20 years, spinal cord stimulation (SCS) has seen development of various paresthesia-free paradigms. Recently, a novel modality emerged (Fast-Acting Sub-perception Therapy, FAST) that engages surrounding inhibition mechanism action. We evaluated long-term, real-world outcomes preferential FAST-SCS use in patients with chronic pain.
Vulvodynia is a chronic pain condition that affects the vulvar area, often resulting in significant discomfort and reduced quality of life. Current treatments for vulvodynia are limited, there need more effective therapeutic options. Acmella oleracea, known its spilanthol content, Boswellia serrata, rich boswellic acids, have been explored their potential analgesic properties management. In this study, vulvodynia-like symptoms were induced female mice using Complete Freund's adjuvant (CFA)....
Chronic lymphatic leukemia (CLL) is the most frequent type of in western countries and when association with del(11q) correlated a worse prognosis. We reported clinical case an 80-year-old patient CLL related to BMI 16.4 kg/m
In the last months of 2019, advent a new virus called SARS-CoV-2 caused spread pandemic disease, COVID-19, that has afflicted patients with chronic pain.We describe COVID-19 patient recently implanted spinal cord stimulator for FBSS, treated Tocilizumab cytokine storm complicating SARS-COV-2 infection. This developed delayed hyperimmune reaction, causing an inflammatory reaction in surgical pocket site, well total remission. The resolution this local occurred after systemic infection by...
Even patients with lymphoproliferative diseases may develop a persistent chronic pain not responsive to usual treatments due changes in antibody production and some like radiotherapy, chemotherapy the administration of monoclonal antibodies, which further impair immune defense induce inflammatory phenomena acting as substrate for pain. Five indolent were treated severe nonresponsive other pain-reliever SCS applied an All One Shot (OS) procedure. For all estimated survival time was 5 years or...
Objective: Osteoarthritis (OA) is the most common cause of chronic knee pain, often a debilitating condition that can significant reduction in functional capacity. Radiofrequency form neuromodulation modulates pain signal transmission and has become progressively more as treatment for pain. This retrospective study aims to evaluate efficacy intraarticular radiofrequency patients with OA Materials Methods: In this study, we included 129 undergoing pulsed using Poisson curve energy...
Spinal cord stimulation (SCS) is effective in treating chronic neuropathic pain. A screening trial typically conducted prior to implantation evaluate whether a patient good candidate for SCS. However, the need has been debated. We evaluated real-world clinical outcomes patients who underwent single-stage procedure receive SCS therapy (i.e., no period) (SS-SCS).