- Pain Management and Treatment
- Spinal Fractures and Fixation Techniques
- Botulinum Toxin and Related Neurological Disorders
- Musculoskeletal pain and rehabilitation
- Intracranial Aneurysms: Treatment and Complications
- Neurogenesis and neuroplasticity mechanisms
- Bone Tumor Diagnosis and Treatments
- Spinal Hematomas and Complications
- Mesenchymal stem cell research
- Sarcoma Diagnosis and Treatment
- Vascular Malformations Diagnosis and Treatment
- Stroke Rehabilitation and Recovery
- Temporomandibular Joint Disorders
- Glioma Diagnosis and Treatment
- Spine and Intervertebral Disc Pathology
- Vascular Malformations and Hemangiomas
- Traumatic Brain Injury Research
- Musculoskeletal synovial abnormalities and treatments
- Pain Mechanisms and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Meningioma and schwannoma management
- Pluripotent Stem Cells Research
- Cervical and Thoracic Myelopathy
- Nerve injury and regeneration
- Neurosurgical Procedures and Complications
Universidad Complutense de Madrid
2018-2025
Hospital Clínico San Carlos
2016-2024
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
2016-2018
Abstract Endogenous neurogenesis in stroke is insufficient to replace the lost brain tissue, largely due lack of a proper biological structure let new cells dwell damaged area. We hypothesized that scaffolds made hyaluronic acid (HA) biomaterials (BM) could provide suitable environment home not only neurons, but also vessels, glia and neurofilaments. Further, addition exogenous cells, such as adipose stem (ASC) increase this effect. Athymic mice were randomly assigned one four group: alone,...
The cortico‐basal ganglia and corticothalamic projections have been extensively studied in the context of neurological psychiatric disorders. Deep brain stimulation (DBS) is known to modulate many these pathways produce desired clinical effect. aim this work describe anatomy main circuits basal using tractography a surgical planning station. We used imaging studies 20 patients who underwent DBS for movement segmented putamen, caudate nucleus (CN), thalamus, subthalamic (STN), we also...
Spinal cord stimulation (SCS) is effective in treating chronic neuropathic pain. A screening trial typically conducted prior to implantation evaluate whether a patient good candidate for SCS. However, the need has been debated. We evaluated real-world clinical outcomes patients who underwent single-stage procedure receive SCS therapy (i.e., no period) (SS-SCS).
Solitary intradural plasmacytomas are extremely rare. We present a case of patient with headache and diagnosis meningiomatosis. Onset symptoms were abrupt neurological deterioration paraparesis. The underwent surgery by craniotomy tumor resection, final pathological findings solitary extramedullary plasmacytoma without evidence multiple myeloma. Of note is the great similarity this infrequent pathology meningiomas need to differentiate it from dural involvement Treatment always includes...
Brain radiation necrosis (BRN) is a side effect of radiotherapy (RT), mainly affects the white matter and can appear from few weeks to several years after RT. It's incidence 3-9% increasing as survival increases. Histopathology (HP) shows avascular damage, demyelination direct necrosis.