Michele Sofia

ORCID: 0000-0001-9397-5306
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About
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Research Areas
  • Pain Management and Opioid Use
  • Palliative Care and End-of-Life Issues
  • Cancer survivorship and care
  • Pharmacological Effects and Toxicity Studies
  • Childhood Cancer Survivors' Quality of Life
  • Pediatric Pain Management Techniques
  • Colorectal Cancer Screening and Detection
  • Cancer Treatment and Pharmacology
  • Pain Management and Placebo Effect
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Musculoskeletal pain and rehabilitation
  • Myofascial pain diagnosis and treatment
  • Pain Mechanisms and Treatments
  • Psychiatric care and mental health services
  • Botulinum Toxin and Related Neurological Disorders
  • Gut microbiota and health
  • Gastric Cancer Management and Outcomes
  • Healthcare Systems and Practices
  • Pain Management and Treatment
  • Oral health in cancer treatment
  • Opioid Use Disorder Treatment
  • Respiratory Support and Mechanisms
  • Nerve Injury and Rehabilitation
  • Interprofessional Education and Collaboration
  • Frailty in Older Adults

Aziende Socio Sanitaria Territoriale Rhodense
2018-2022

ATS Sardegna (Italy)
2021

Background: The aim of this study was to identify potential variables influencing the clinical presentation breakthrough cancer pain (BTP). Methods: Cancer patients with a diagnosis BTP were enrolled. Demographic and characteristics, as well background characteristics collected. Multivariate analyses conducted assess correlation between examined. Results: Data 4016 analysed. Average daily number episodes 2.4, mean intensity 7.5, duration 43.3 min. A short onset observed in 68.9% patients. In...

10.3390/cancers10060175 article EN Cancers 2018-06-01

<sec> <title>BACKGROUND</title> the gut microbiota is attracting increasing interest as an initiator of colorectal cancer. It has been observed that microbial imbalance in and cancer tissue facilitated by a Western type diet, rich meat, sugars, refined grains, while Mediterranean low saturated fat fibers, promotes eubiosis, results reduced risk developing </sec> <title>OBJECTIVE</title> to analyze compare patients with metastatic undergoing first-line chemotherapy +/- biological agent...

10.2196/preprints.72950 preprint EN cc-by 2025-02-21

There is an increasing requirement to assess outcomes, but few measures have been tested for advanced medical illness. We aimed test the validity, reliability and responsiveness of Palliative care Outcome Scale (POS), analyse predictors change after transition palliative care. Phase 1: multicentre, mixed method study comprising cognitive qualitative interviews with patients staff, cultural refinement adaption. 2: consecutive cancer on admission 8 inpatient hospices 7 home-based teams were...

10.1186/s12904-016-0095-6 article EN cc-by BMC Palliative Care 2016-02-26

An ongoing national multicenter survey [Italian Oncologic Pain multiSetting Multicentric Survey (IOPS-MS)] is evaluating the characteristics of breakthrough cancer pain (BTP) in different clinical settings. Preliminary data from first 1500 patients with BTP enrolled this study are presented here. Thirty-two centers involved survey. A diagnosis was performed by a standard algorithm. Epidemiological data, Karnofsky index, stage disease, presence and sites metastases, oncologic treatment,...

10.1007/s12325-016-0440-4 article EN cc-by-nc Advances in Therapy 2016-11-21

PURPOSE A large proportion of patients with cancer suffer from breakthrough pain (BTcP). Several unmet clinical needs concerning BTcP treatment, such as optimal opioid dosages, are being investigated. In this analysis the hypothesis, we explore an unsupervised learning algorithm whether distinct subtypes exist and they can provide new insights into practice. METHODS Partitioning around a k-medoids on data set BTcP, previously collected by Italian Oncologic Pain Survey group, was used to...

10.1200/po.20.00158 article EN cc-by JCO Precision Oncology 2020-11-01

Patients with irreversible malignant and non-malignant diseases have comparable mortality rates, symptom burdens, quality of life issues; however, non-cancer patients seldom receive palliative care (PC) or it late in their disease trajectory. To explore the characteristics receiving PC northern Italy, as well features outcomes care, we retrospectively analyzed charts all initiating regimens during 2019 three publicly funded departments Italy’s populous Lombardy region. We recorded baseline...

10.3390/healthcare10061031 article EN Healthcare 2022-06-02

The aim of the present work was to evaluate knowledge and prescriptive habits clinicians involved in management chronic non cancer pain (CNCP), with a special focus on use opioids.A Delphi method used. A Board specialists elaborated discussed series statements, based available literature personal clinical expertise, about particularly controversial topics pathophysiology treatment. Panel experts field management, selected by Board, invited vote proposed indicating level agreement 5-point...

10.2147/jpr.s314206 article EN cc-by-nc Journal of Pain Research 2021-10-01

. A model of continuity care for not residents through medical-nursing teleconsultation in a Hub & Spoke network.The Seasonal Continuity Care (CAS) is service the Bergamo Health Protection Agency that provides medical and healthcare services, guaranteeing outpatient or home to Italian foreign tourists seasonal workers during months July August. The Covid-19 pandemic shortage doctors made it impossible provide 2021 as previous summer seasons.To activate CAS with involvement nurses.A...

10.1702/3974.39536 article EN PubMed 2023-06-07

Background: Despite the extensive literature, Breakthrough cancer Pain (BTcP) is still under-diagnosed and under-treated.Although pain affects quality of life, primary care physicians do not seem to play a role in management patients with BTcP.Objectives: Point out clinical characteristics that can help general practitioner identify patient early particular BTcP. Methods:We studied data base 4,016 enrolled IOPS-MS study order which parameters BTP be detected by physicians. Results:The...

10.29011/2577-2228.100056 article EN Journal of Community Medicine & Public Health 2019-07-18

Dyspnea can be assessed using self-rating scales but, as death approaches, self-reporting becomes difficult. The validated Respiratory Distress Observation Scale measures dyspnea distress. aim of this study was to develop the Italian version and examine its psychometric properties. This a cross-sectional study, analyzing cultural linguistic validation, content validity, Eighty-nine palliative care subjects were enrolled validate Scale. Patients had an average age 74.5 (SD, 11.6) years, 52%...

10.1097/njh.0000000000000736 article EN Journal of Hospice and Palliative Nursing 2021-02-08
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