- Respiratory Support and Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Airway Management and Intubation Techniques
- Cardiac Arrest and Resuscitation
- Intensive Care Unit Cognitive Disorders
- Tracheal and airway disorders
- Anesthesia and Sedative Agents
- Sepsis Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Family and Patient Care in Intensive Care Units
- Patient Safety and Medication Errors
- Emergency and Acute Care Studies
- Acute Kidney Injury Research
- Mechanical Circulatory Support Devices
- Anesthesia and Neurotoxicity Research
- Delphi Technique in Research
- Trauma Management and Diagnosis
- Heart Failure Treatment and Management
- Ultrasound in Clinical Applications
- Neonatal Respiratory Health Research
- Aortic Disease and Treatment Approaches
- Medical Malpractice and Liability Issues
- Disaster Response and Management
- Enhanced Recovery After Surgery
- Nosocomial Infections in ICU
University of Insubria
2002-2024
Ospedale di Circolo e Fondazione Macchi
2020-2024
Aziende Socio Sanitarie Territoriale dei Sette Laghi
2022-2023
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2009-2020
Vita-Salute San Raffaele University
2011-2020
Istituti di Ricovero e Cura a Carattere Scientifico
1989-2020
Guangzhou Medical University
2019
IRCCS Ospedale San Raffaele
1998-2019
Monash University
2018-2019
First Affiliated Hospital of Guangzhou Medical University
2019
Mechanical ventilation contributes to diaphragmatic atrophy and dysfunction, few techniques exist assess function: the purpose of this study was quantify diaphragm in a population critically ill mechanically ventilated patients with ultrasound identify risk factors that can worsen activity.Prospective observational study.ICU 1,200-bed university hospital.Newly intubated adult patients.Diaphragm thickness zone apposition measured daily ultrasound, from first day mechanical till discharge main...
There is no consensus on which drugs/techniques/strategies can affect mortality in the perioperative period of cardiac surgery. With aim identifying these measures, and suggesting measures for prioritized future investigation we performed first international conference this topic.The was a continuous internet-based process with final meeting June 28th 2010 Milan at Vita-Salute University. Participants included 340 anesthesiologists, surgeons cardiologists from 65 countries all over world. A...
Objectives: We aimed to identify all treatments that affect mortality in adult critically ill patients multicenter randomized controlled trials. also evaluated the methodological aspects of these studies, and we surveyed clinicians' opinion usual practice for selected interventions. Data Sources: MEDLINE/PubMed, Scopus, Embase were searched. Further articles suggested inclusion from experts cross-check references. Study Selection: fulfilled following criteria: publication a peer-reviewed...
Intubation is frequently required for patients in the intensive care unit (ICU) but associated with high morbidity and mortality mainly emergency procedures presence of severe organ failures. Improving intubation procedure a major goal all ICU physicians worldwide, videolaryngoscopy may play relevant role.Videolaryngoscopes are heterogeneous entity, including Macintosh blade-shaped optical laryngoscopes, anatomically shaped blade without tube guide guide, which might have theoretical...
The COVID‐19 outbreak poses continued struggles due to the unprecedented number of patients admitted intensive care units and overwhelming need for mechanical ventilation. We report a preliminary case series 32 with who underwent elective tracheostomies after mean intubation period 15 days (range, 9‐21 days). procedure was performed percutaneous (10 cases) open (22 surgical techniques. Neither procedure‐related complications nor viral transmission health workers observed. Our experience...
Support measures currently represent the mainstay of treatment for fulminant myocarditis, while effective and safe anti-inflammatory therapies remain an unmet clinical need. However, experimental evidence indicates that inhibition pro-inflammatory cytokine interleukin 1 (IL-1) is against both myocardial inflammation contractile dysfunction. We thus evaluated with IL-1 receptor antagonist anakinra in a case heart failure secondary to myocarditis. A 65-year-old man T cell lymphoma developed...
Use of noninvasive ventilation (NIV) for the treatment patients with acute respiratory failure (ARF) has greatly increased in last decades. In contrast, increasing knowledge its effectiveness and physician confidence managing this technique have been accompanied by a declining number available ICU beds. As consequence, application NIV outside reported as growing phenomenon. Previously published surveys highlighted great heterogeneity use, clinical indications, settings, efficacy. Moreover,...
The efficacy and safety of continuous positive airway pressure respiratory physiotherapy outside the Intensive Care Unit during a pandemic.In this cohort study performed in February-May 2020 large teaching hospital Milan, COVID-19 patients with adult distress syndrome receiving (positive end-expiratory =10 cm H<inf>2</inf>O, FiO<inf>2</inf>=0.6, daily treatment duration: 4×3h-cycles) including pronation were followed-up.Of 90 acute (ARDS) treated (45/90, 50% pronated at least once) median...