A5049619836- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Sedative Agents
- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Intensive Care Unit Cognitive Disorders
- Hemodynamic Monitoring and Therapy
- Cardiovascular Issues in Pregnancy
- Cardiac Arrest and Resuscitation
- Pregnancy and preeclampsia studies
- Anesthesia and Neurotoxicity Research
- Sleep and Wakefulness Research
- Mechanical Circulatory Support Devices
- Tracheal and airway disorders
- Birth, Development, and Health
- Cardiac Structural Anomalies and Repair
- Neuroscience and Neuropharmacology Research
- Healthcare Operations and Scheduling Optimization
- Maternal and fetal healthcare
- Intraoperative Neuromonitoring and Anesthetic Effects
- Traumatic Brain Injury and Neurovascular Disturbances
- Hospital Admissions and Outcomes
- Patient Safety and Medication Errors
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Sepsis Diagnosis and Treatment
University of Chicago
2016-2025
GlaxoSmithKline (China)
2024
University of Chicago Medical Center
2014-2023
Barro Colorado Island
2016-2023
NorthShore University HealthSystem
2015-2022
American Society of Anesthesiologists
2019-2021
Committee on Publication Ethics
2021
Preeclampsia Foundation
2021
Massachusetts General Hospital
2016-2021
Harvard University
2016-2021
P RACTICE Guidelines are systematically developed rec- ommendations that assist the practitioner and patient in making decisions about health care.These recommendations may be adopted, modified, or rejected according to clinical needs constraints, not intended replace local institutional policies.In addition, Practice by American Society of Anesthesiologists (ASA) as standards absolute requirements, their use cannot guarantee any specific outcome.Practice subject revision warranted evolution...
These practice guidelines update the Practice Guidelines for Central Venous Access: A Report by American Society of Anesthesiologists Task Force on Access, adopted in 2011 and published 2012. updated are intended use anesthesiologists individuals under supervision an anesthesiologist may also serve as a resource other physicians, nurses, or healthcare providers who manage patients with central venous catheters. Supplemental Digital Content is available text.
Anesthesiologist-directed preoperative medicine clinics are used to prepare patients for the administration of anesthesia and surgery. Studies have shown that such a clinic reduces testing consults, but few studies examined impact on day The authors tested whether visit an (APMC) would reduce day-of-surgery case cancellations and/or delays.The conducted retrospective chart review all surgical cases during 6-month period at University Chicago Hospitals. Case rates first-start delay over were...
To revise the "Clinical Practice Guidelines for Sustained Use of Sedatives and Analgesics in Critically Ill Adult" published Critical Care Medicine 2002. The American College assembled a 20-person, multidisciplinary, multi-institutional task force with expertise guideline development, pain, agitation sedation, delirium management, associated outcomes adult critically ill patients. force, divided into four subcommittees, collaborated over six years person, via teleconferences, electronic...
Objective: The mechanisms leading to worse outcomes in African-American (AA) women with preeclampsia/eclampsia remain unclear. Our objective was identify racial differences maternal comorbidities, peripartum characteristics, and fetal outcomes. Methods/Results: When compared white preeclampsia/eclampsia, AA had an increased unadjusted risk of inpatient mortality (OR 3.70, 95% CI: 2.19–6.24). After adjustment for covariates, in-hospital remained higher than that 2.85, 1.38–5.53), while the...
Background Some neurophysiologic similarities between sleep and anesthesia suggest that an anesthetized state may reverse effects of deprivation. The effect on homeostasis, however, is unknown. To test the hypothesis recovery from deprivation occurs during anesthesia, authors followed 24 h in rat with a 6-h period either ad libitum or propofol compared subsequent characteristics. Methods With animal care committee approval, electroencephalographic/electromyographic electrodes intrajugular...
Abstract Background Although opioids remain the standard therapy for treatment of postoperative pain, prevalence opioid misuse is rising. The extent to which abuse or dependence affects readmission rates and healthcare utilization not fully understood. It was hypothesized that surgical patients with a history would have higher utilization. Methods A retrospective cohort analysis performed undergoing major operating room procedures in 2013 2014 using National Readmission Database. Patients...
Hypertensive disorders of pregnancy (HDP) are associated with subclinical changes in cardiac function. Although the mechanism underlying this finding is unknown, elevated levels soluble antiangiogenic proteins such as fms-like tyrosine kinase-1 (sFlt1) and endoglin (sEng) myocardial dysfunction may play a role. We hypothesized that these contribute to development HDP. prospectively studied 207 pregnant women HDP nonhypertensive controls evaluated whether global longitudinal strain (GLS)...
Since the first recognition of a cluster novel respiratory viral infections in China late December 2019, intensivists United States have watched with growing concern as severe acute syndrome coronavirus 2 (SARS-CoV-2) virus-now named disease 2019 (COVID-19)-have spread to hospitals States. Because COVID-19 is extremely transmissible and can progress form failure, potential overwhelm available critical care resources high management patients has been thrust into spotlight. arrived January...
OBJECTIVE: To test the ability of a hospital-wide, bundled quality-improvement initiative to improve postpartum maternal blood pressure control and adherence follow-up among patients with hypertensive disorders pregnancy. METHODS: This consisted bundle clinical interventions including health care professional patient education, dedicated nurse educator, protocols for pregnancy in inpatient, outpatient readmission setting. We implemented this starting January 2019 at University Chicago. The...
Background Unexpected awareness is a rare but well-described complication of general anesthesia that has received increased scientific and media attention in the past few years. Transformed electroencephalogram monitors, such as Bispectral Index monitor, have been advocated tools to prevent unexpected recall. Methods The authors conducted power analysis estimate how many patients would be needed an appropriately powered study demonstrate monitor reduces awareness, well cost assess using for...
Background Sleep and anesthesia differ physiologically but produce a similar loss of responsiveness to environmental stimuli. Recent data suggest that neuronal networks active in naturally occurring sleep also play role the anesthetized state. Changes propensity may then modify response anesthetic agents. The authors tested hypothesis sleep-deprived rats would require less than rested achieve responsiveness. Methods Rats were subjected 24-h period either deprivation or ad libitum activity....
Objective: Cardiogenic shock (CS) may occur during pregnancy and dramatically worsen peripartum outcomes. Methods: We analyzed the National Inpatient Sample from 2002 to 2013 describe incidence of, risk factors for outcomes of CS pregnancy. Results: Of 53,794,192 hospitalizations analyzed, 2044 were complicated by CS. The mortality rate in women with was 18.81% versus 0.02% without. It occurs more often postpartum (58.83%) as compared delivery (23.47%) or antepartum (17.70%)...
Awake flexible bronchoscopic intubation is guideline recommended when asleep airway management considered difficult.1 Intravenous sedatives, opioids, nerve blocks, and topical local anesthetics are often used to facilitate awake intubation. Considerable variation in the methodologies document process evident previous studies meta-analyses.2 Although dexmedetomidine may be associated with fewer desaturation episodes, no consensus anesthetic approach has emerged as clearly superior minimizing...
Hynson, James M. MD; Tung, Avery Guevara, Jason E. Katz, Jeffrey A. Glick, Shapiro, William MD Author Information
Background: Toxic epidermal necrolysis syndrome is a devastating disease, with mortality rates ranging between 20 and 60 percent. This study evaluated an alternative treatment approach using antishear wound care compared outcomes the severity of illness score for toxic (SCORTEN) system. Methods: Records 48 patients histopathologic diagnosis treated burn equivalent critical from September 1985 to April 2004 were reviewed. Observed data those expected SCORTEN, standardized ratio was...