A5060267238- Intensive Care Unit Cognitive Disorders
- Anesthesia and Sedative Agents
- Anesthesia and Neurotoxicity Research
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrest and Resuscitation
- Pharmacological Effects and Toxicity Studies
- Healthcare Decision-Making and Restraints
- Respiratory Support and Mechanisms
- Epilepsy research and treatment
- Sepsis Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Family and Patient Care in Intensive Care Units
- Antibiotics Pharmacokinetics and Efficacy
- Venous Thromboembolism Diagnosis and Management
- Heparin-Induced Thrombocytopenia and Thrombosis
- Antibiotic Use and Resistance
- Electrolyte and hormonal disorders
- Thermal Regulation in Medicine
- Patient Safety and Medication Errors
- Alcoholism and Thiamine Deficiency
- Opioid Use Disorder Treatment
- Non-Invasive Vital Sign Monitoring
- Pharmaceutical Practices and Patient Outcomes
- Adrenal Hormones and Disorders
- Pharmaceutical studies and practices
Tufts University
2014-2023
Maine Medical Center
2013-2022
Maine Medical Center
2002-2021
Mayo Clinic in Florida
2017
University of Saint Mary
2017
Valley Hospital Medical Center
2017
University of Pittsburgh
2016
Northeastern University
2016
McGill University
2016
Neurosciences Institute
2013
To update and expand the 2013 Clinical Practice Guidelines for Management of Pain, Agitation, Delirium in Adult Patients ICU.Thirty-two international experts, four methodologists, critical illness survivors met virtually at least monthly. All section groups gathered face-to-face annual Society Critical Care Medicine congresses; virtual connections included those unable to attend. A formal conflict interest policy was developed a priori enforced throughout process. Teleconferences electronic...
Jacobi, Judith PharmD, FCCM, BCPS; Fraser, Gilles L. FCCM; Coursin, Douglas B. MD; Riker, Richard R. Fontaine, Dorrie RN, DNSc, FAAN; Wittbrodt, Eric T. PharmD; Chalfin, Donald MD, MS, Masica, Michael F. MPH; Bjerke, H. Scott Coplin, William M. Crippen, David W. Fuchs, Barry D. Kelleher, Ruth RN; Marik, Paul E. MDBCh, Nasraway, Stanley A. Jr Murray, J. PhD, Peruzzi, Lumb, Philip MB, BS, FCCM. Author Information
Objective Subjective scales to assess agitation and sedation in adult intensive care unit (ICU) patients have rarely been tested for validity or reliability. We revised prospectively the Sedation-Agitation Scale (SAS) interrater reliability compared it with Ramsay scale Harris test construct validity. Design A convenience sample of ICU was simultaneously independently examined by pairs trained evaluators using SAS, Ramsay, Scales. Setting Multidisciplinary 34-bed a nonuniversity, academic...
Section:ChooseTop of pageAbstract <<ContentsSummary Recommendation...IntroductionMethodsResults1SummaryReferencesCITING ARTICLES
Clinical practice guidelines are published and promoted, often by professional societies, because they provide a current transparently analyzed review of relevant research written with the aim to guide clinical practice. The 2018 Pain, Agitation/sedation, Delirium, Immobility (rehabilitation/mobilization), Sleep (disruption) (PADIS) (1) first 1) builds on this mission updating 2013 PAD (2); 2) adding two inextricably related care topics (immobility sleep); 3) including patients as...
Objective To describe the level of sedation for a cohort mechanically ventilated adult intensive care unit (ICU) patients using validated subjective and objective tools. Design Prospective convenience sample. Setting Multidisciplinary 34-bed ICU at Maine Medical Center, 599-bed nonuniversity, academic medical center. Patients Sixty-three were monitored during 64 episodes ventilatory support. Measurements Main Results prospectively evaluated by one trained investigator revised...
To evaluate the safety and efficacy of continuous infusion haloperidol in treating agitated critically ill adult patients.Case series patients treated with followed to hospital discharge, during a 6-month period.A 34-bed multidisciplinary intensive care unit (ICU) 598-bed nonuniversity, tertiary teaching hospital.Consecutive sample eight requiring mechanical ventilation who had severe agitation which was refractory intermittent bolus treatment benzodiazepines, narcotics,...
Although numerous reports have described interventions designed to influence antibiotic utilization, our knowledge none been evaluated in a randomized study.Adult inpatients receiving 1 or more of 10 designated parenteral antibiotics for 3 days during 3-month period were an intervention (n = 141) and control 111) group using unblocked, computer-generated random number table. Obstetric patients those seen infectious disease consultation excluded. The received antibiotic-related suggestions...
To revise the "Clinical Practice Guidelines for Sustained Use of Sedatives and Analgesics in Critically Ill Adult" published Critical Care Medicine 2002. The American College assembled a 20-person, multidisciplinary, multi-institutional task force with expertise guideline development, pain, agitation sedation, delirium management, associated outcomes adult critically ill patients. force, divided into four subcommittees, collaborated over six years person, via teleconferences, electronic...
This clinical practice guideline addresses six questions related to liberation from mechanical ventilation in critically ill adults. It is the result of a collaborative effort between American Thoracic Society and College Chest Physicians.A multidisciplinary panel posed Population, Intervention, Comparator, Outcomes format. A comprehensive literature search evidence synthesis was performed for each question, which included appraising certainty (i.e., quality evidence) using Grading...
Study Objective. To study the frequency, duration, severity, and treatment of agitation in patients intensive care unit (ICU) to determine if elderly represent a distinct population. Design. Prospective cohort study. Setting. Tertiary care, 10‐bed, multidisciplinary ICU. Patients. All older than 18 years age admitted for longer 24 hours during 4‐month period. Interventions. None. Measurements Main Results. One hundred thirty were studied 916 patient‐days; 63 (48%) (> 65 yrs). Nurses...
<h3>Background:</h3> Although numerous reports have described interventions designed to influence antibiotic utilization, our knowledge none been evaluated in a randomized study. <h3>Methods:</h3> Adult inpatients receiving 1 or more of 10 designated parenteral antibiotics for 3 days during 3-month period were an intervention (n=141) and control (n=111) group using unblocked, computer-generated random number table. Obstetric patients those seen infectious disease consultation excluded. The...
Objective: Retrospective analyses of several trials suggest etomidate may be unsafe for intubation in patients with sepsis. We evaluated the association and mortality a large cohort septic to determine if single-dose was associated increased in-hospital mortality. Design Setting: study at Philips eICU Research Institute ICU clinical database. Interventions: None. Patients: Among 741,036 monitored from 2008 through 2010, we identified 2,014 adults intubated 4–96 hrs after admission, having...
Introduction Enteral clonidine represents a potentially less costly alternative to dexmedetomidine for sedation in intensive care unit (ICU) patients. This study describes our practice of transitioning selected adult ICU patients from with focus on efficacy, safety, and drug acquisition costs. Methods We conducted single-center prospective observational pilot January through March 2014. Consecutive 18 years older treated transitioned were followed. The transition was assessed five phases:...