Donald B. Chalfin

ORCID: 0000-0002-4196-3095
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Sepsis Diagnosis and Treatment
  • Healthcare Policy and Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Health Systems, Economic Evaluations, Quality of Life
  • Global Health Care Issues
  • Hemodynamic Monitoring and Therapy
  • Emergency and Acute Care Studies
  • Healthcare cost, quality, practices
  • Trauma and Emergency Care Studies
  • Intensive Care Unit Cognitive Disorders
  • Primary Care and Health Outcomes
  • Machine Learning in Healthcare
  • Disaster Response and Management
  • Palliative Care and End-of-Life Issues
  • Healthcare Operations and Scheduling Optimization
  • Liver Disease Diagnosis and Treatment
  • Respiratory Support and Mechanisms
  • Family and Patient Care in Intensive Care Units
  • Nursing Diagnosis and Documentation
  • Esophageal and GI Pathology
  • Ethics in medical practice
  • COVID-19 diagnosis using AI
  • Liver Disease and Transplantation
  • Economic and Financial Impacts of Cancer
  • Trauma, Hemostasis, Coagulopathy, Resuscitation

Siemens Healthcare (United States)
2020-2025

Jefferson College
2016-2025

Thomas Jefferson University
2016-2025

Jefferson College of Health Sciences
2016-2022

Engineering Associates (United States)
2018

Astute Medical (United States)
2018

University of North Carolina Hospitals
2018

Université Libre de Bruxelles
2015

St. Luke's-Roosevelt Hospital Center
2014

Abbott Fund
2010-2013

Jacobi, Judith PharmD, FCCM, BCPS; Fraser, Gilles L. FCCM; Coursin, Douglas B. MD; Riker, Richard R. Fontaine, Dorrie RN, DNSc, FAAN; Wittbrodt, Eric T. PharmD; Chalfin, Donald MD, MS, Masica, Michael F. MPH; Bjerke, H. Scott Coplin, William M. Crippen, David W. Fuchs, Barry D. Kelleher, Ruth RN; Marik, Paul E. MDBCh, Nasraway, Stanley A. Jr Murray, J. PhD, Peruzzi, Lumb, Philip MB, BS, FCCM. Author Information

10.1097/00003246-200201000-00020 article EN Critical Care Medicine 2002-01-01

Numerous factors can cause delays in transfer to an intensive care unit for critically ill emergency department patients. The impact of is unknown. We aimed determine the association between "boarding" (holding admitted patients pending transfer) and outcomes patients.This was a cross-sectional analytical study using Project IMPACT database (a multicenter U.S. patients). Patients from (2000-2003) were included divided into two groups: boarding >or=6 hrs (delayed) vs. <6 (nondelayed)....

10.1097/01.ccm.0000266585.74905.5a article EN Critical Care Medicine 2007-04-17

Objective: Early identification of causative microorganism(s) in patients with severe infection is crucial to optimize antimicrobial use and patient survival. However, current culture-based pathogen slow unreliable such that broad-spectrum antibiotics are often used insure coverage all potential organisms, carrying risks overtreatment, toxicity, selection multidrug-resistant bacteria. We compared the results obtained using a novel, culture-independent polymerase chain reaction/electrospray...

10.1097/ccm.0000000000001249 article EN cc-by-nc-nd Critical Care Medicine 2015-09-01

We hypothesized that a "closed" intensive care unit (ICU) was more efficient an "open" one. ICU admissions were retrospectively analyzed before and after closure at one hospital; prospective analysis in with open nearby done. Illness severity gauged by the Mortality Prediction Model (MPM0). Outcomes included mortality, length of stay (LOS), hospital LOS, mechanical ventilation (MV). There no differences age, MPM0, use MV. LOS lower when (ICU LOS: 6.1 versus 12.6 d, p < 0.0001; retrospective...

10.1164/ajrccm.157.5.9708039 article EN American Journal of Respiratory and Critical Care Medicine 1998-05-01

Background: Critically ill patients admitted to intensive care units (ICUs) are thought gain an added survival benefit from management by critical physicians, but evidence of this is scant. Objective: To examine the association between hospital mortality in critically and physicians. Design: Retrospective analysis a large, prospectively collected database patients. Setting: 123 ICUs 100 U.S. hospitals. Patients: 101 832 adults. Measurements: Through use random-effects logistic regression,...

10.7326/0003-4819-148-11-200806030-00002 article EN cc-by Annals of Internal Medicine 2008-06-03

Adult critical care services are a large, expensive part of U.S. health care. The current agenda for response to workforce shortages and rising costs has largely been determined by members the profession without input from other stakeholders. We sought elicit perceived problems solutions delivery broad set stakeholders.A consensus process involving purposive sampling identified stakeholders, preconference Web-based survey, 2-day conference.Participants represented healthcare providers,...

10.1097/01.ccm.0000259535.06205.b4 article EN Critical Care Medicine 2007-02-23

The demand for medical services such as critical care is likely to often exceed supply. In the setting of these constraining conditions, institutions and individual providers must use some moral framework distributing available resources efficiently equitably. Guidelines are therefore provided triage critically ill patients. There several general principles that should guide decision making: advocate patients; members provider team collaborate; be restricted in an equitable system; decisions...

10.1001/jama.271.15.1200 article EN JAMA 1994-04-20

<h3>Objective.</h3> —To evaluate the fiscal impact and cost-effectiveness of monoclonal antibodies against gram-negative endotoxin (MAbGNE) in treatment presumed sepsis. <h3>Design.</h3> —A decision analysis model was developed from (1) data two phase III trials that studied E5 or HA-1A MAbGNE, (2) financial 1405 septic patients who required intensive care at a large tertiary hospital. <h3>Setting.</h3> —Intensive unit (ICU) with <h3>Patients.</h3> —The trial evaluated 468 patients, study...

10.1001/jama.1993.03500020083037 article EN JAMA 1993-01-13

Abstract Background Global metabolic dysfunction-associated steatotic liver disease (MASLD) prevalence is estimated at 30% and projected to reach 55.7% by 2040. In the Veterans Affairs (VA) healthcare system, an 1.8 million veterans have steatohepatitis (MASH). Methods Adult patients risk for MASLD in a VA system underwent Fibrosis-4 (FIB-4) Enhanced Liver Fibrosis (ELF®) testing. Referral rates cost savings were compared among 6 noninvasive testing (NIT) strategies using these 2 tests...

10.1093/jalm/jfae154 article EN The Journal of Applied Laboratory Medicine 2025-01-15

Objective To examine and describe the relation between age disposition in patients undergoing tracheostomy. Design Retrospective analysis of a statewide database. Setting All acute care hospitals New York state. Patients (n = 6,353) >or=to18 yrs who were discharged from hospital during 1993 with final diagnosis-related groups code 483. Interventions None. Measurements Main Results The disposition, according to six codes (other facility, residential healthcare other home, home services,...

10.1097/00003246-199706000-00015 article EN Critical Care Medicine 1997-06-01

Older patients, patients with malignancies, and those admitted to ICUs utilize a disproportionate amount of hospital resources. To evaluate the combined impact age diagnosis malignancy on ICU utilization outcome, we reviewed care provided all 1,212 medical/surgical in specializing treatment cancer between January 1, 1986 December 31, 1987. Patients 19 64 yr (young) were compared 65 74 (young-old) greater than or equal 75 (old-old) respect nutritional support (total parenteral nutrition...

10.1097/00003246-199007000-00002 article EN Critical Care Medicine 1990-07-01

The SARS-CoV-2 virus has caused tremendous healthcare burden worldwide. Our focus was to develop a practical and easy-to-deploy system predict the severe manifestation of disease in patients with COVID-19 an aim assist clinicians triage treatment decisions. proposed predictive algorithm is trained artificial intelligence-based network using 8,427 patient records from four systems. model provides severity risk score along likelihoods various clinical outcomes, namely ventilator use mortality....

10.1016/j.isci.2021.103523 article EN cc-by iScience 2021-11-27

Background: The demand for critical care services in the United States is likely to increase as a result of aging population and standards from Leapfrog Group intensivist physician staffing. However, physicians, nurses, other health professionals will significantly outpace supply because severe shortages. Participants: This article summarizes recommendations Framing Options Critical Care (FOCCUS) Task Force, group comprised representatives Society Medicine, American Association Critical-Care...

10.1097/01.ccm.0000126403.89958.80 article EN Critical Care Medicine 2004-04-28

Abstract Objectives Central line–associated bloodstream infection ( CLABSI ) is a preventable nosocomial infection. Simulation‐based training in sterile technique during central venous catheter CVC placement for emergency medicine EM residents, and its effect on changing the medical intensive care unit MICU practice of routine replacement s placed under department ED ), has not been evaluated. Methods Emergency residents received simulation‐based between May 2008 September 2010. Between June...

10.1111/acem.12551 article EN Academic Emergency Medicine 2014-12-31

Cancer accounts for approximately 13% of all deaths worldwide, and in 2010 the estimated total cost cancer USA was more than US$263 billion. Biomarker use screening, monitoring, diagnosis treatment optimization has potential to improve patient outcomes reduce costs associated with inappropriate (or suboptimal) therapeutic regimens. Since a new technology may have additional initial cost, policy question arises regarding whether improvement is attained at 'reasonable' compared existing...

10.2217/pme.12.87 article EN Personalized Medicine 2012-11-01

AbstractPurpose: The US Food and Drug Administration recently approved the first 4th-generation HIV test. This study evaluated cost-effectiveness of assay versus a 3rd-generation test in screening for infections United States. Methods: An exploratory microsimulation model was developed that follows hypothetical individuals simulates course HIV/AIDS, treatment with highly active antiretroviral therapy, transmissions. Results: With 1% prevalence, 1.5 million 4th- resulted detection 266...

10.1310/hct1301-11 article EN HIV Clinical Trials 2012-02-01
Coming Soon ...