A5007157416- Liver Disease Diagnosis and Treatment
- Vaccine Coverage and Hesitancy
- vaccines and immunoinformatics approaches
- SARS-CoV-2 and COVID-19 Research
- Health Systems, Economic Evaluations, Quality of Life
- Acute Ischemic Stroke Management
- Hepatocellular Carcinoma Treatment and Prognosis
- Stroke Rehabilitation and Recovery
- COVID-19 Pandemic Impacts
- Liver Diseases and Immunity
- Peripheral Artery Disease Management
- Liver Disease and Transplantation
- COVID-19 epidemiological studies
- Cardiac Imaging and Diagnostics
- Clinical practice guidelines implementation
- Global Health Care Issues
- Vascular Malformations Diagnosis and Treatment
- Systemic Sclerosis and Related Diseases
- Biological Research and Disease Studies
- Tuberculosis Research and Epidemiology
- Advanced Database Systems and Queries
- Nutrition and Health in Aging
- Efficiency Analysis Using DEA
- Dementia and Cognitive Impairment Research
- Agricultural risk and resilience
Siemens Healthcare (United States)
2021-2025
Health Innovations (United States)
2022-2023
Feinstein Institute for Medical Research
2022-2023
National Academy of Sciences
2014-2015
National Academy of Medicine
2015
NAFLD is a common cause of liver disease. To determine the optimal testing strategy for patients with advanced fibrosis, several factors such as diagnostic accuracy, failure rates, costs examinations, and potential treatment options need to be considered. The purpose this study was cost-effectiveness combination involving vibration-controlled transient elastography (VCTE) versus magnetic resonance (MRE) frontline imaging fibrosis.A Markov model developed from US perspective. base-case...
Hepatocellular carcinoma (HCC) surveillance is currently performed using a one-size-fits-all strategy with ultrasound plus AFP (US + AFP). There increasing interest in risk-stratified and precision strategies incorporating individual risk variance test performance; however, the cost-effectiveness of these approaches has not been evaluated.
We measure the benefit to society created by preventing COVID-19 deaths through a marginal increase in early social distancing. exploit county-level rainfall on last weekend before statewide lockdown phase of pandemic. After controlling for historical rainfall, temperature, and state fixed-effects, current is plausibly exogenous instrument A one percent decrease population leaving home creates an average 132 dollars per county resident within 2 weeks. The impacts earlier distancing compound...
Abstract Background Global metabolic dysfunction-associated steatotic liver disease (MASLD) prevalence is estimated at 30% and projected to reach 55.7% by 2040. In the Veterans Affairs (VA) healthcare system, an 1.8 million veterans have steatohepatitis (MASH). Methods Adult patients risk for MASLD in a VA system underwent Fibrosis-4 (FIB-4) Enhanced Liver Fibrosis (ELF®) testing. Referral rates cost savings were compared among 6 noninvasive testing (NIT) strategies using these 2 tests...
We measure the benefit to society created by preventing COVID-19 deaths through a marginal increase in early social distancing. exploit county-level rainfall on last weekend before statewide lockdown phase of pandemic. After controlling for historical rainfall, temperature, and state fixed-effects, current is plausibly exogenous instrument A one percent decrease population leaving home creates an average 132 dollars per county resident within 2 weeks. The impacts earlier distancing compound...
Evidence has shown that endovascular thrombectomy (EVT) treatment improves clinical outcomes. Yet, its benefit remains uncertain in patients with large established infarcts as defined by ASPECTS (Alberta Stroke Program Early CT Score) <6. This study evaluates the cost-effectiveness of EVT, compared standard care (SC), acute ischemic stroke (AIS) 3-5.
Clinical outcomes following endovascular thrombectomy (EVT) for acute ischemic stroke (AIS) treatment are highly time sensitive. Remote robotic (RR)-EVT systems may be capable of mitigating delays in patient transfer from a primary center (PSC) to comprehensive/thrombectomy-capable center. However, health economic evidence is needed assess the costs and benefits an RR-EVT system. Therefore, authors this study aimed determine whether performing suspected AIS patients at PSC as opposed...
Policy and investment decisions regarding new health technologies are often complex. They require a careful balancing of multiple perspectives differing objectives. On some occasions, policymakers or analysts approaching these have access to cost-effectiveness cost-benefit analyses help guide their decisions, but almost invariably such inadequate.
Background Rapid time to reperfusion is essential minimize morbidity and mortality in acute ischemic stroke due large vessel occlusion (LVO). We aimed evaluate the workflow times when utilizing a direct-to-angiography suite (DTAS) pathway for patients with suspected presenting at comprehensive center compared conventional CT pathway. Methods developed discrete-event simulation (DES) model DTAS timelines pathway, varying admission NIHSS score treatment eligibility criteria. Model parameters...
Introduction: Stroke thrombectomy (ST) is cost-effective for acute ischemic stroke (AIS) patients with large-vessel occlusion and low Alberta Program Early CT Score (ASPECTS <6) compared non-endovascular standard care (SC). However, previous cost-effectiveness analyses (CA) were based on data that not specific to ASPECTS or had limited generalizability (e.g., Japanese 3-5). As new results from two 2023 clinical trials included <6 emerged Western countries China, we aim update the of ST...
We appreciate Dr. Tapper's remarks on our paper1. As mentioned, due to the lack of longitudinal studies with MRE, modeling is a potent approach connect disease progression early detection and diagnosis. In addition, by raising questions objections model, you allow us opportunity clarify elaborate upon several points that deserve further attention. While average age patient in model 50 years old, life span modeled based CDC, National Vital Statistics Reports tables for US population. The...