Alessandro Belletti
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrest and Resuscitation
- Hemodynamic Monitoring and Therapy
- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Sepsis Diagnosis and Treatment
- Mechanical Circulatory Support Devices
- Pneumothorax, Barotrauma, Emphysema
- Anesthesia and Sedative Agents
- Pleural and Pulmonary Diseases
- COVID-19 Clinical Research Studies
- Heart Failure Treatment and Management
- Acute Kidney Injury Research
- Long-Term Effects of COVID-19
- Anesthesia and Neurotoxicity Research
- Vitamin C and Antioxidants Research
- Cardiac Structural Anomalies and Repair
- Electrolyte and hormonal disorders
- Venous Thromboembolism Diagnosis and Management
- Aortic aneurysm repair treatments
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Trauma Management and Diagnosis
- Cardiac Valve Diseases and Treatments
- Renal function and acid-base balance
- Cardiac Ischemia and Reperfusion
Vita-Salute San Raffaele University
2016-2025
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2016-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2025
Austin Hospital
2019-2023
The University of Melbourne
2021
IRCCS Ospedale San Raffaele
2021
Sapienza University of Rome
2016
Epatocentro Ticino
2016
Hospital de Santa Marta
2016
Società Italiana di Medicina Generale
1988
Acute left ventricular dysfunction is a major complication of cardiac surgery and associated with increased mortality. Meta-analyses small trials suggest that levosimendan may result in higher rate survival among patients undergoing surgery.
Describe characteristics, daily care and outcomes of patients with coronavirus disease 2019 (COVID-19) acute respiratory distress syndrome (ARDS).Case series 73 patients.Large tertiary hospital in Milan.Mechanically ventilated confirmed COVID-19 admitted to the intensive unit (ICU) between 20 February 2 April 2020.Demographic clinical data were collected identify predictors early mortality.Of included study, most male (83.6%), median age was 61 years (interquartile range [IQR], 54-69 years),...
At the end of 2019, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak spread from China all around world, causing thousands deaths. In Italy, hardest hit region was Lombardy, with first reported case on 20 February 2020. San Raffaele Scientific Institute — a large tertiary hospital and research centre in Milan, Italy immediately involved management public health emergency. Since beginning outbreak, elective surgical activity rapidly reduced areas were simultaneously...
Volatile (inhaled) anesthetic agents have cardioprotective effects, which might improve clinical outcomes in patients undergoing coronary-artery bypass grafting (CABG).We conducted a pragmatic, multicenter, single-blind, controlled trial at 36 centers 13 countries. Patients scheduled to undergo elective CABG were randomly assigned an intraoperative regimen that included volatile (desflurane, isoflurane, or sevoflurane) total intravenous anesthesia. The primary outcome was death from any...
Meropenem is a widely prescribed β-lactam antibiotic. exhibits maximum pharmacodynamic efficacy when given by continuous infusion to deliver constant drug levels above the minimal inhibitory concentration. Compared with intermittent administration, administration of meropenem may improve clinical outcomes.To determine whether reduces composite mortality and emergence pandrug-resistant or extensively drug-resistant bacteria compared in critically ill patients sepsis.A double-blind, randomized...
Acute kidney injury (AKI) is a serious and common complication of cardiac surgery, for which reduced perfusion key contributing factor. Intravenous amino acids increase recruit renal functional reserve. However, the efficacy in reducing occurrence AKI after surgery uncertain.
In patients undergoing cardiac surgery, a reduced preoperative left ventricular ejection fraction (LVEF) is common and associated with worse outcome. Available outcome data for these address specific surgical procedures, mainly coronary artery bypass graft (CABG). Aim of our study was to investigate perioperative surgery on low pre-operative LVEF broad range procedures. Data from ≤40 % at university hospital were reviewed analyzed. A subgroup analysis ≤30 also performed. total 7313 underwent...
Background: There is no information on acute kidney injury (AKI) and continuous renal replacement therapy (CRRT) among invasively ventilated coronavirus disease 2019 (COVID-19) patients in Western healthcare systems. Objective: To study the prevalence, characteristics, risk factors outcome of AKI CRRT COVID-19 patients. Methods: Observational a tertiary care hospital Milan, Italy. Results: Among 99 patients, 72 (75.0%) developed 17 (17.7%) received CRRT. Most stage 1 (33 [45.8%]), while 15...