- Intensive Care Unit Cognitive Disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Anesthesia and Sedative Agents
- Anesthesia and Neurotoxicity Research
- Emergency and Acute Care Studies
- Homelessness and Social Issues
- Smoking Behavior and Cessation
- Alcohol Consumption and Health Effects
- Substance Abuse Treatment and Outcomes
- Patient-Provider Communication in Healthcare
- Alcoholism and Thiamine Deficiency
- Health, psychology, and well-being
- Frailty in Older Adults
- Hemophilia Treatment and Research
- Family and Disability Support Research
- Trauma and Emergency Care Studies
- Patient Satisfaction in Healthcare
- Health and Medical Studies
- Childhood Cancer Survivors' Quality of Life
- Venous Thromboembolism Diagnosis and Management
- Hip and Femur Fractures
- Cardiac Imaging and Diagnostics
- Retinal Imaging and Analysis
- Retinal Diseases and Treatments
- Cardiovascular Disease and Adiposity
Charité - Universitätsmedizin Berlin
2015-2024
Humboldt-Universität zu Berlin
2017-2023
Freie Universität Berlin
1996-2023
University Medical Center Utrecht
2017
St Helens Hospital
2017
University of Münster
2010-2015
Zero to Three
2015
Klinik für Schlafmedizin
2010
University Hospital Münster
2010
Robert Koch Institute
2009
Postoperative delirium (POD) remains a common, dangerous and resource-consuming adverse event but is often preventable. The whole peri-operative team can play key role in its management. This update to the 2017 ESAIC Guideline on prevention of POD evidence-based consensus-based considers literature between 01 April 2015, 28 February 2022. search terms broad were identical those used first version guideline published 2017. was defined accordance with DSM-5 criteria. had be measured validated...
Background: One-third of injured patients treated in the emergency department (ED) have an alcohol use disorder (AUD). Few are screened and receive counseling because ED staff little time for additional tasks. We hypothesized that computer technology can screen provide intervention reduces at-risk drinking (British Medical Association criteria) patients. Methods: In all, 3,026 subcritically admitted to were AUD using a laptop administered Identification Test (AUDIT) assessed motivation...
There is little knowledge as to whether the chronicity of a disease affects patients' desire for participation.To study participation preferences vary according type disease. DESIGN, PARTICIPANTS AND METHODS: Data 1,393 patients from six trials with different medical conditions (hypertension, depression, breast cancer, schizophrenia, multiple sclerosis, minor traumas) were pooled and analysed, using regression analysis controlling socio-demographic variables.Younger age, better education...
Abstract Background Frailty is a frequent and underdiagnosed functional syndrome involving reduced physiological reserves an increased vulnerability against stressors, with severe individual socioeconomic consequences. A routine frailty assessment was implemented at our preoperative anaesthesia clinic to identify patients risk. Objective This study examines the relationship between status incidence of in-hospital postoperative complications in elderly surgical across several disciplines....
Purpose This randomized controlled, clinical prospective interventional trial was aimed at exploring the effect of patient empowerment on short- and long-term outcomes after major oncologic surgery in elderly cancer patients. Methods performed from February 2011 to January 2014 two tertiary medical centers Germany. The study included patients aged 65 years older undergoing elective for gastro-intestinal, genitourinary, thoracic cancer. were randomly assigned intervention group, i.e. through...
Objective: The Alcohol Use Disorder Identification Test (AUDIT) has been recommended as a screening tool to detect patients who are appropriate candidates for brief, preventive alcohol interventions. Lower AUDIT cutoff scores have proposed women; however, the value remains unknown. primary purpose of this study was determine optimal cutpoint detecting problems in subcritically injured male and female treated emergency department (ED). An additional whether computerized is feasible setting....
Abstract Objective: Limited data are available on health‐related quality of life (HR‐QoL) in pediatric stroke survivors. The aim the present study was to assess HR‐QoL by self‐assessment and parent/proxy‐assessment children adolescents who survived a first episode. Methods: We investigated survivors (71 preschool [G1] 62 school children/adolescents [G2]) 169 healthy controls. assessed patients parents/proxies with generic KINDL‐R questionnaire exploring overall well‐being 6 subdimensions...
A low ankle-brachial blood pressure index (ABI) is an established risk marker for cardiovascular disease and mortality in the general population, but little known about its prognostic value individuals with acute ischemic stroke or transient attack (TIA).An inception cohort of 204 patients TIA was followed up a mean 2.3 years. At baseline, underwent ABI measurement were assessed factors, comorbidities, cervical intracranial artery stenosis. The association between (</=0.9) composite outcome...
Aim: This emergency department (ED) study compared the value of plasma ethyl glucuronide (EtG) testing with information about alcohol consumption obtained using standard biomarkers gamma-glutamyltransferase (GGT) and carbohydrate-deficient transferring (CDT) AUDIT questionnaire. Methods: Minimally injured clinically non-intoxicated male patients (n = 81) admitted to an ED were screened regarding their consumption, computerized questionnaire a paper-and-pencil assessment including type,...
Sense of coherence (SOC) is a resource for health and quality life (QoL) in adults. The aim this investigation was to prospectively evaluate the association between SOC QoL adolescents with congenital heart defects (CHDs).This an observational study among 770 aged 14 17 years from national CHD register. measured at baseline SOC-L9 questionnaire. follow-up 12 months later. For this, we used KINDL-R (revidierter KINDer Lebensqualitätsfragebogen) questionnaire overall well-being 6 subscales...
Post-operative delirium and post-operative cognitive dysfunction (POCD) are both common but it has not been clarified how closely they associated. We aimed to assess the possible relationship in a secondary analysis of data from 'Surgery Depth anaesthesia Cognitive outcome'- study.We included patients aged ≥ 60 years undergoing non-cardiac surgery planned for longer than min. Delirium was assessed according Diagnostic Statistical Manual Mental Disorders IV criteria post-anaesthesia care unit...
Telomere length (TL) is considered a marker of biological aging and has been associated with the presence various coronary risk factors in patients. Much less known about relationships between TL classic other populations. We measured peripheral blood leukocytes 343 middle-aged donors (mean age 40.2 ± 12.4 years; 201 men, 142 women) using quantitative polymerase chain reaction. Median was 0.86 (range: 0.48-1.85) relative units. In linear regression analyses natural log-transformed T to S...
Alcohol screening and brief interventions have been shown to reduce alcohol-related morbidity in injured patients. Use of self-report questionnaires such as the Disorder Identification Test (AUDIT) is recommended optimum method. We hypothesized that accuracy enhanced by combined use AUDIT biomarkers alcohol patients.The study was conducted emergency department a large, urban, university hospital. Patients were evaluated with AUDIT, blood sampled determine carbohydrate-deficient transferrin,...
Anliegen: Untersuchung des Zusammenhangs zwischen Migrationsstatus und depressiven Symptomen in der älteren Bevölkerung Deutschland. Methode: In einer Querschnittstudie mit repräsentativen Stichprobe ab 50-jährigen deutschen (n = 2890) wurden depressive Symptome EURO-D-Skala erfasst. Ergebnisse: Migranten (definiert als Personen eigener Migrationserfahrung) wiesen eine höhere Prävalenz depressiver (EURO-D ≥ 4 Punkte) auf (28 %) Nichtmigranten (19 %). Nach Adjustierung für relevante...
Background: There is some evidence that patients’ outcomes improve if they are involved in shared decision making (SDM). A chronic pain clinic or premedication visit could be adequate settings for the implementation of SDM. So far, preference involvement and their desire information have not been tested anesthesiological settings. Methods: group patients was compared with a respect to SDM, perceived care. The autonomy index (API, measuring information) care scale (PICS, perception easier by...
Objective Aim of this study was to evaluate the association between preoperative health-related quality life (HRQoL) and mortality in a cohort elderly patients (>65 years) with gastrointestinal, gynecological genitourinary carcinomas. Design Prospective pilot study. Setting Tertiary university hospital Germany. Patients Between June 2008 July 2010 after ethical committee approval written informed consent, 126 scheduled for onco-surgery were included. Prior surgery as well 3 12 months...