A5031712142- Nausea and vomiting management
- Urban Transport and Accessibility
- Autoimmune Bullous Skin Diseases
- Acne and Rosacea Treatments and Effects
- Atrial Fibrillation Management and Outcomes
- Psoriasis: Treatment and Pathogenesis
- IgG4-Related and Inflammatory Diseases
- Cardiac Imaging and Diagnostics
- Business and Management Studies
- Eosinophilic Disorders and Syndromes
- Older Adults Driving Studies
- Cardiac Valve Diseases and Treatments
- Congenital Heart Disease Studies
- Neuroendocrine Tumor Research Advances
- Lipoproteins and Cardiovascular Health
- Migration, Aging, and Tourism Studies
- Cardiac Arrhythmias and Treatments
- Balance, Gait, and Falls Prevention
- Intraperitoneal and Appendiceal Malignancies
- Thyroid and Parathyroid Surgery
- University-Industry-Government Innovation Models
- Otitis Media and Relapsing Polychondritis
- Inflammatory Myopathies and Dermatomyositis
- Regional Development and Policy
- Spinal Hematomas and Complications
Hospital de São João
2014-2025
Centro Hospitalar de Trás os Montes e Alto Douro
2024
Algarve Biomedical Center
2024
Centro Hospitalar do Porto
2016-2024
Centro Hospitalar de Vila Nova de Gaia
2024
Hospital da Luz
2023
Universidade Federal do Acre
2023
Centro Hospitalar de Entre o Douro e Vouga E.P.E.
2023
University of Aveiro
2018-2021
Escola Superior de Saúde Egas Moniz
2021
Antisynthetase syndrome (ASSD) is a rare clinical condition that characterized by the occurrence of classic triad, encompassing myositis, arthritis, and interstitial lung disease (ILD), along with specific autoantibodies are addressed to different aminoacyl tRNA synthetases (ARS). Until now, it has been unknown whether presence ARS might affect presentation, evolution, outcome ASSD. In this study, we retrospectively recorded time onset, characteristics, clustering triad findings, survival...
The heterogeneous syndromes caused by germline mutations in genes belonging to the RAS/mitogen-activated protein kinase pathway are often referred as RASopathies. Abnormal activation of this plays a key role development these disorders. Pathogenic variants RASA1 gene cause an autosomal dominant syndrome called capillary malformation-arteriovenous malformation type 1 characterized broad phenotypic variability, even within same family. In syndrome, multifocal and arteriovenous malformations...
Peripheral arterial disease is a frequently underdiagnosed that can severely affect the quality of life. We present clinical case 62-year-old smoker post-menopause woman with mild stroke. Further investigation revealed severe disseminated disease. Due to multidisciplinary and timely interventions, peripheral ischemia was prevented successfully. In fact, this patient had polyvascular Despite its worst prognosis than either coronary artery disease, cerebrovascular or alone, still...
Abstract Aims Drug‐refractory electrical storm (ES) is a life‐threatening medical emergency. We describe the use of venoarterial extracorporeal membrane oxygenation (VA‐ECMO) in drug‐refractory ES without reversible trigger, for which specific guideline recommendations are still lacking. Methods and results Retrospective observational study four Iberian centres on indications, treatment, complications, outcome not associated with acute coronary syndromes, decompensated heart failure, drug...
Gastric carcinoma (GC) represents the most common cause of death in patients with variable immunodeficiency (CVID). However, a limited number cases have been characterised so far. In this study, we analysed clinical features, bacterial/viral infections, detailed morphology and immune microenvironment nine CVID GC. The study included automated digital counts CD20+, CD4+, CD8+, FOXP3+, GATA3+ CD138+ cells, as well evaluation PD-L1 expression. Twenty-one GCs from non-CVID were used control...
A fluorescent dye was decorated with water-soluble pyridinium groups in order to be applied the detection of cyclodextrins or DNA. The displays an enhancement its emission intensity when internal rotations are restricted due formation inclusion complex upon interaction In vivo, probe can stain protein aggregates a selectivity comparable widely used Proteostat®.
Aging populations pose a challenge to many policy areas. Although the importance of built environment on citizens’ mobility and quality life has been widely acknowledged in literature, research focusing elderly people is relatively recent still scarce namely Portugal. This article aims at understanding how local stakeholders perceive occupational activities targeted elderly. The focuses municipality Viseu, medium-sized city located NUTSII Centro Region Portugal, considered twice be best live...
This article analyzes the relation between location and surrounding built environment of residential care facilities for older adults their users' mobility. For this, interviews were carried out in 14 Portugal to understand degree which users leave walking, what main motivation perceived barriers are. In locu observations assess walkability map services amenities at a 400 m 800 radius also conducted. It was found that many on foot do so access specific service. These findings stress...
Background The COVID-19 pandemic brought changes in the pattern of care use. A significant increase volume emergencies was expected. However, a decrease observed worldwide. Methods An observational, analytical and cross-sectional study all records emergency episodes patients aged 18 years or older admitted to services University Porto Hospital Centre (2018–2022) were analysed. Results During pandemic, reduction episode admissions (up 40% during lockdowns), an pre-emergency services,...
Malignant peritoneal mesothelioma (MPM) is a rare neoplasm with low incidence rate worldwide but high morbidity and mortality rates. Due to its rarity, the studies are scarce. We present case of 73-year-old woman admitted internal medicine unit constitutional syndrome, abdominal pain, ascites. Throughout investigation, aspects suggestive carcinomatosis were identified. An extensive study was then carried out in an attempt identify primary tumor, which proved be unsuccessful. During two weeks...
Abstract BACKGROUND: Solid tumors are a common cause of secondary thrombocytosis, which has been identified as prognostic factor in various cancers. However, the impact thrombocytosis on prognosis gastric cancer is not yet well defined. The aim this study was to assess prevalence and value patients with cancer. METHODS: This retrospective carcinoma treated surgically, curative intent, our hospital, Centro Hospitalar Vila Nova de Gaia/Espinho, between January 2009 December 2019. Clinical...
An 11-year-old girl, with known acquired immunodeficiency syndrome, thought to be from vertical transmission of human virus (HIV), presented a pink, friable nodule on her upper lip, which had been slowly growing for 4 months (Figure 1). Her disease was stage C3 (CD4+ T cells: 40/mm3; viral load: 332000 copies/mL). She treated empirically, first topical mupirocin, and then oral flucloxacillin (25 mg/kg/day 7 days), itraconazole (5 14 days) without improvement. There no history local trauma,...
Background: Liver transplantation is a therapeutic modality in situations of advanced liver disease whose success depends on how patients deal with new and complex regimen their daily lives.Objectives: To develop flowchart to support nursing decision-making the self-management transplant patients.Methodology: Qualitative longitudinal study conducted between January December 2013 center, using retrospective content analysis records consensus meetings nurses.Results: The included following...