Ana Lebreiro

ORCID: 0000-0001-7827-4042
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About
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Research Areas
  • Cardiac Arrhythmias and Treatments
  • Cardiac Valve Diseases and Treatments
  • Atrial Fibrillation Management and Outcomes
  • Congenital Heart Disease Studies
  • Cardiac pacing and defibrillation studies
  • Cardiac electrophysiology and arrhythmias
  • Aortic Disease and Treatment Approaches
  • Connective tissue disorders research
  • Cardiovascular Effects of Exercise
  • Coronary Artery Anomalies
  • Cardiovascular Function and Risk Factors
  • Cardiomyopathy and Myosin Studies
  • Cardiovascular Syncope and Autonomic Disorders
  • Cardiac Imaging and Diagnostics
  • Pulmonary Hypertension Research and Treatments
  • Cardiac Structural Anomalies and Repair
  • Cardiovascular and Diving-Related Complications
  • Antimicrobial Resistance in Staphylococcus
  • Streptococcal Infections and Treatments
  • Cardiovascular Issues in Pregnancy
  • Lipoproteins and Cardiovascular Health
  • Infective Endocarditis Diagnosis and Management
  • Alcoholism and Thiamine Deficiency
  • BRCA gene mutations in cancer
  • Omental and Epiploic Conditions

Hospital de São João
2012-2024

Universidade do Porto
2011-2014

Centro Hospitalar do Porto
2014

Pulmonary vein isolation (PVI) guided by the Ablation Index (AI) has shown high acute and mid-term efficacy in treatment of paroxysmal atrial fibrillation (AF). Previous data before AI-era had suggested that wide-area circumferential ablation (WACA) was preferable to ostial ablation. However, with use AI, we hypothesize is non-inferior WACA can improve outcomes AF.Prospective, multicentre, non-randomized, non-inferiority study consecutive patients were referred for AF from January 2020...

10.1093/europace/euad160 article EN cc-by-nc EP Europace 2023-06-01

Since the widespread availability of contact-force sensing catheters, need for a waiting period after pulmonary vein isolation (PVI) has not been reassessed. We aim to evaluate whether is still necessary PVI guided by ablation Index (AI).Prospective, multicenter, randomized study consecutive patients referred paroxysmal atrial fibrillation (AF) from May 2019 February 2020. Patients were in 1:1 ratio with versus without 20 min. Acute (PV) reconnection adenosine challenge was primary endpoint....

10.1111/jce.15568 article EN Journal of Cardiovascular Electrophysiology 2022-05-31

Abstract Aims Drug‐refractory electrical storm (ES) is a life‐threatening medical emergency. We describe the use of venoarterial extracorporeal membrane oxygenation (VA‐ECMO) in drug‐refractory ES without reversible trigger, for which specific guideline recommendations are still lacking. Methods and results Retrospective observational study four Iberian centres on indications, treatment, complications, outcome not associated with acute coronary syndromes, decompensated heart failure, drug...

10.1002/ehf2.14756 article EN cc-by-nc-nd ESC Heart Failure 2024-04-11

Resumo Fundamento: O software ablation index (AI) permitiu melhorar os resultados da ablação de fibrilação atrial (FA), mas as taxas recorrência permanecem significativas. Biomarcadores séricos específicos têm sido associados a essa recorrência. Objetivos: Avaliar se certos biomarcadores podem ser utilizados (individualmente ou combinados) para predizer FA pós guiada pelo AI. Métodos: Estudo multicêntrico, observacional, prospectivo pacientes consecutivos, encaminhados janeiro 2018 março...

10.36660/abc.20230544 article PT cc-by Arquivos Brasileiros de Cardiologia 2024-01-01

Abstract Aims We aimed to assess the acute and midterm efficacy of premature ventricular contraction (PVC) ablation guided by multielectrode point-by-point (PbP) mapping. Methods results This is a retrospective, international multicentre study consecutive patients referred for PVC in 10 hospital centres from January 2017 December 2021. Based on mapping approach, two cohorts were identified: ‘Multipolar group’, where dedicated high-density catheter was employed, ‘PbP performed with catheter....

10.1093/europace/euae148 article EN cc-by EP Europace 2024-05-29

Despite successful repair of aortic coarctation (AC), systemic hypertension (HTN) can persist in a significant percentage patients. Exercise-induced HTN is also common these patients, although its clinical significance still unclear. In this study we aimed to assess the prevalence exercise-induced adult patients with repaired AC.We retrospectively reviewed records aged >18 years AC followed at an congenital heart disease outpatient clinic tertiary care center. Demographic and data including...

10.1016/j.repc.2013.02.018 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2013-11-01

Background: There are currently several electrocardiographic algorithms to locate the accessory pathway (AP) in patients with Wolff-Parkinson-White (WPW) syndrome. Objective: To compare ability of identifying location AP WPW pattern referred for ablation. Methods: Observational, cross-sectional, retrospective study 111 syndrome The electrocardiogram (ECG) obtained prior ablation was analyzed by an experienced observer who consecutively applied seven identify non-invasively AP. We then...

10.5935/abc.20160132 article EN cc-by-nc Arquivos Brasileiros de Cardiologia 2016-01-01

Background: Low cholesterol levels are associated with a worse outcome in patients heart failure (HF). Use of statins HF remains controversial. We aimed to assess whether the prognosis intrinsically low differed from that those pharmacologically induced cholesterol. Materials and Methods: conducted retrospective cohort study on 464 ambulatory attending specialized clinic. Patients were cross-classified according statin therapy admission total level (low <150 mg/dL ≥150 mg/dL): (1)...

10.1177/1074248411429967 article EN Journal of Cardiovascular Pharmacology and Therapeutics 2011-12-14

Despite successful repair of aortic coarctation (AC), systemic hypertension (HTN) can persist in a significant percentage patients. Exercise-induced HTN is also common these patients, although its clinical significance still unclear. In this study we aimed to assess the prevalence exercise-induced adult patients with repaired AC. We retrospectively reviewed records aged >18 years AC followed at an congenital heart disease outpatient clinic tertiary care center. Demographic and data including...

10.1016/j.repce.2013.02.020 article PT cc-by-nc-nd Revista Portuguesa de Cardiologia (English Edition) 2013-11-01

Aortocardiac fistulas are rare, especially if they develop after an aortic valve replacement surgery. We report the case of a 54-year-old male submitted to and implantation ascending prosthetic graft, complaining exertional dyspnea, who was found have significant shunt between root right ventricle (RV), de novo moderate pulmonary hypertension. At catheterization laboratory, left-to-right confirmed (Qp:Qs = 1.9:1). Contrast angiography aorta showed flow into ventricular cavity, fistulous...

10.1002/ccd.23222 article EN Catheterization and Cardiovascular Interventions 2011-07-06

Wolff-Parkinson-White (WPW) syndrome is the most common manifestation of ventricular pre-excitation and mostly found in individuals with no structural heart disease. Although risk malignant arrhythmias low, sudden cardiac death (SCD) as first clinical WPW well documented, atrial fibrillation (AF) a rapid response main mechanism involved. Unfortunately, signs are sometimes under-diagnosed under-treated. We describe case 31-year-old man who was admitted an irregular wide complex tachycardia...

10.1016/j.repc.2019.06.008 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2022-09-14

Abstract Background Supraventricular tachycardia (SVT) are common cardiac arrhythmias, and catheter ablation has proven to be a very effective treatment, but exposes patients healthcare providers radiation. "Near Zero Fluoroscopy" (NZF) techniques, utilizing advanced imaging, aim reduce radiation exposure while maintaining efficacy. Purpose To present an analysis of near-zero fluoroscopy in SVT procedures, tertiary center, since its implementation. Methods We prospectively enrolled 446...

10.1093/europace/euae102.777 article EN cc-by-nc EP Europace 2024-05-01

Background: Hypertrophic Cardiomyopathy (HCM) is a common genetic disorder with wide variability in anatomic and clinical expression. However, data on Papillary Muscles (PMs) are scarce. Therefore, we aimed to analyze PMs characteristics by magnetic resonance imaging HCM population. Methods: We retrospectively evaluated 50 patients (pts) who performed Cardiac Magnetic Resonance (CMR) our institution, between 2008 2012. All pts had preserved Left Ventricular Ejection Fraction (LVEF) were...

10.1093/eurheartj/eht309.p2921 article EN European Heart Journal 2013-08-02

O ecocardiograma transtorácico é fundamental na avaliação de doentes operados a tetralogia Fallot. A dilatação da raiz aorta uma complicação descrita. Neste estudo, avaliámos sua prevalência e potenciais preditores. Estudo consecutivo adultos diâmetro interno máximo ao nível dos seios Valsalva (DAo) foi avaliado por transtorácico, em paraesternal eixo longo. Definimos dois grupos: grupo 1 com (DAo ≥ 38 mm) 2 sem < mm). Incluímos 53 (idade média 32 ± 10 anos); intervalo médio desde cirurgia...

10.1016/j.repc.2012.10.010 article PT cc-by-nc-nd Revista Portuguesa de Cardiologia 2013-06-01

Infective endocarditis is a well-known clinical entity. However, despite improved diagnostic techniques and advances in treatment options, left-sided native valve infective remains serious disease with high morbidity mortality, especially cases caused by Staphylococcus aureus. The heterogeneity of sometimes prevents rapid recognition, correct diagnosis timely treatment, which are essential to reduce the mortality associated this disease. We report case 62-year-old man, admitted for atrial...

10.1016/j.repc.2012.04.015 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2012-11-20

Abstract Tall stature is a common feature of both Marfan syndrome and XYY syndrome. Differential diagnosis between these entities has important prognostic implications. We report the case 21-year-old young man with previously known syndrome, in whom identification fibrilin-1 mutation was determinant to establish an appropriate diagnosis, medical follow-up, genetic counselling.

10.1017/s1047951111001776 article EN Cardiology in the Young 2011-11-04

Transthoracic echocardiography is an important tool after tetralogy of Fallot repair, which aortic root dilatation a recognized complication. In this study we aimed to assess its prevalence and potential predictors. We consecutively assessed adult patients by transthoracic divided them into two groups based on the maximum internal diameter at sinuses Valsalva in parasternal long-axis view: group 1 with (≥38 mm) 2 without (<38 mm). A total 53 were included, mean age 32±10 years, time since...

10.1016/j.repce.2013.06.003 article PT cc-by-nc-nd Revista Portuguesa de Cardiologia (English Edition) 2013-06-01

Idiopathic ventricular fibrillation (IVF) is diagnosed in patients who survive sudden cardiac arrest (SCA), preferably with documented (VF), without any identifiable structural or electrical abnormality. Current evidence provides limited guidance on the diagnosis and follow-up of these patients. Our aim was to assess clinical outcomes survivors an aborted SCA attributed IVF.

10.1016/j.repc.2024.04.001 article EN cc-by-nc-nd Revista Portuguesa de Cardiologia 2024-04-12

Abstract Background: Ablation Index (AI) software has allowed better atrial fibrillation (AF) ablation results, but recurrence rates remain significant. Specific serum biomarkers have been associated with this recurrence. Objectives: To evaluate whether certain could be used (either individually or combined) to predict arrhythmia after AI-guided AF ablation. Methods: Prospective multicenter observational study of consecutive patients referred for from January 2018 March 2021. Hemoglobin,...

10.36660/abc.20230544i article EN cc-by Arquivos Brasileiros de Cardiologia 2024-01-01
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