A5102733902- Cardiac Structural Anomalies and Repair
- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Cardiovascular Effects of Exercise
- Coronary Artery Anomalies
- Congenital Heart Disease Studies
- Cardiac Arrhythmias and Treatments
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Takotsubo Cardiomyopathy and Associated Phenomena
- Cardiac electrophysiology and arrhythmias
- Aortic Disease and Treatment Approaches
- Heart Failure Treatment and Management
- Cardiac pacing and defibrillation studies
- Cardiac Arrest and Resuscitation
- Pericarditis and Cardiac Tamponade
- Lysosomal Storage Disorders Research
- Viral Infections and Immunology Research
- Cardiac tumors and thrombi
- Kawasaki Disease and Coronary Complications
- Vascular anomalies and interventions
- Pulmonary Hypertension Research and Treatments
- Parathyroid Disorders and Treatments
- Congenital heart defects research
- Trypanosoma species research and implications
Universidade do Porto
2012-2025
Administração Regional de Saúde de Lisboa e Vale do Tejo
2025
Hospital de São João
2012-2023
Centro Hospitalar do Porto
2017
Sociedad Española de Cardiología
2016
Centro Cardiologico Monzino
2012
Guilan University of Medical Sciences
2012
Faculty (United Kingdom)
2012
Oslo University Hospital
2012
Marmara University
2012
In order to further characterize oestrogen production and metabolism during bovine pregnancy, free (f) conjugated (c) estrone (El), total oestrogens (tfcOe) (tfOe) were determined as marker in blood plasma respectively urine feces of 10 pregnant cows. For the determination individual blood, samples days 240, 200, 160, 100, 60, 30, 5 prior parturition pooled free, sulfo (sc)- glucuconjugated (gc) forms El, 17β-estradiol (E2β) 17α-estradiol (E2α) obtained following differential enzyme...
Cardiac remodeling is manifested as changes in size, shape and function of the heart. We studied prevalence, prognosis predictors left ventricular reverse (LVRR) idiopathic dilated cardiomyopathy (IDCM) after optimized medical therapy.A total 113 IDCM patients were followed for 7.1±5.6 years. LVRR was defined an increase 10 units ejection fraction (EF) decrease diastolic diameter (LVDD), absence resynchronization therapy.Baseline EF 27±8% LVDD index 37.1±6.3 mm/m(2). occurred 34.5% within...
Fabry disease is a rare X-linked lysosomal storage disorder caused by mutations in the alpha-galactosidase gene. The most frequent cardiac presentation of cardiomyopathy characterized left ventricular (LV) hypertrophy, usually concentric. Heart affected females tends to be clinically recognized later than males and complications are frequently reported cause death with disease. There few data regarding association between LV noncompaction. We report case 30-year-old asymptomatic woman,...
We describe the clinical characteristics, management and outcomes of patients hospitalized with acute heart failure in a south-west European cardiology department. sought to identify determinants length stay rehospitalization or death during 12-month follow-up period. This was retrospective cohort study including all admitted 2010 primary secondary diagnosis failure. Death readmission were followed through 2011. Of 924 admitted, 201 (21%) had failure, 107 (53%) whom new-onset The main...
Dilated cardiomyopathy (DCM) is a disease of the heart muscle characterized by ventricular dilatation and impaired systolic function. Familial forms account for 30-50% cases. Autosomal dominant inheritance predominant pattern transmission. Causal genetic variants have been identified in several genes molecular diagnosis has implications counseling risk stratification. We aimed to estimate frequency basis DCM Portugal. performed multicenter study unrelated patients, recruited between 2013...
Stress-induced cardiomyopathy, also known as 'broken heart syndrome' or Takotsubo is characterized by transient systolic dysfunction of the apical and/or mid segments left ventricle, in absence significant coronary artery disease. We report case a 56-year-old male patient with chronic obstructive pulmonary disease (COPD), stress-induced cardiomyopathy associated use ipratropium bromide, administered context an acute exacerbation COPD. A cardiomiopatia associada ao stress, também conhecida...
The authors present a clinical case of coronary artery spasm in 62-year-old woman undergoing elective aortic valve replacement surgery for regurgitation. On admission at ICU, the patient developed marked hemodynamic and electrical instability. Emergent angiography demonstrated pronounced distal portion right artery, apparently related to compression this vessel by chest drain tube.
A 49-year-old woman, with no relevant family history, was admitted in 1996 for arrhythmic storm polymorphic ventricular tachycardia (torsade de pointes) which degenerated into fibrillation. Iatrogenic causes were excluded, the electrocardiogram (ECG) normal and there structural heart disease. She refused cardioverter-defibrillator implantation. Treatment begun amiodarone, she took irregularly. remained asymptomatic until 2014 when a new torsade pointes, refractory to antiarrhythmic therapy...
Calcium plays a key role in heart muscle contraction and relaxation. Hypocalcemic failure is rare potentially reversible disturbance, which reflects this intrinsic relationship. The authors present the case of 35-year-old woman who developed acute during early postoperative period following total thyroidectomy. echocardiogram showed severe global left ventricular dysfunction. Laboratory tests hypocalcemia new-onset hypoparathyroidism. Cardiac catheterization angiographically normal coronary...
Calcium plays a key role in heart muscle contraction and relaxation. Hypocalcemic failure is rare potentially reversible disturbance, which reflects this intrinsic relationship. The authors present the case of 35-year-old woman who developed acute during early postoperative period following total thyroidectomy. echocardiogram showed severe global left ventricular dysfunction. Laboratory tests hypocalcemia new-onset hypoparathyroidism. Cardiac catheterization angiographically normal coronary...
Fabry disease is a rare X-linked lysosomal storage disorder caused by mutations in the alpha-galactosidase gene. The most frequent cardiac presentation of cardiomyopathy characterized left ventricular (LV) hypertrophy, usually concentric. Heart affected females tends to be clinically recognized later than males and complications are frequently reported cause death with disease. There few data regarding association between LV noncompaction. We report case 30-year-old asymptomatic woman,...
Simultaneous en bloc replacement of the ascending aorta and aortic valve by a composite graft, as first described Bentall De Bono in 1968 with later modifications, has become standard surgical technique treatment aneurysms root associated severe dysfunction. Despite good results overall, it is still considerable perioperative mortality dire complications long run. We report case giant pseudoaneurysm compressing right heart chambers communicating ventricle presenting rapidly progressing...
O ecocardiograma transtorácico é fundamental na avaliação de doentes operados a tetralogia Fallot. A dilatação da raiz aorta uma complicação descrita. Neste estudo, avaliámos sua prevalência e potenciais preditores. Estudo consecutivo adultos diâmetro interno máximo ao nível dos seios Valsalva (DAo) foi avaliado por transtorácico, em paraesternal eixo longo. Definimos dois grupos: grupo 1 com (DAo ≥ 38 mm) 2 sem < mm). Incluímos 53 (idade média 32 ± 10 anos); intervalo médio desde cirurgia...
Left ventricular noncompaction is an unusual but increasingly recognized cardiomyopathy, the etiology of which still not definitely established. Clinical presentation includes a wide spectrum scenarios, including heart failure, thromboembolism and malignant arrhythmias, with half deaths occurring suddenly. Early detection LVNC therefore essential to prevent sudden cardiac death. To our knowledge, this first report presence sympathetic nervous dysfunction, assessed by...
Transthoracic echocardiography is an important tool after tetralogy of Fallot repair, which aortic root dilatation a recognized complication. In this study we aimed to assess its prevalence and potential predictors. We consecutively assessed adult patients by transthoracic divided them into two groups based on the maximum internal diameter at sinuses Valsalva in parasternal long-axis view: group 1 with (≥38 mm) 2 without (<38 mm). A total 53 were included, mean age 32±10 years, time since...
A 36-year-old woman was referred for medical evaluation prior to non-cardiac surgery. She healthy and only complained of sporadic palpitations. The 12-lead electrocardiogram showed sinus rhythm left bundle branch block. Transthoracic echocardiography revealed a normally functioning, slightly dilated ventricle (LV), with the interventricular septum bulging toward right (RV), which elongated wrapped around LV (Figure 1; Supplementary material Videos S1 S2). papillary muscles were structurally...
Cardiac remodeling is manifested as changes in size, shape and function of the heart. We studied prevalence, prognosis predictors left ventricular reverse (LVRR) idiopathic dilated cardiomyopathy (IDCM) after optimized medical therapy. A total 113 IDCM patients were followed for 7.1±5.6 years. LVRR was defined an increase 10 units ejection fraction (EF) decrease diastolic diameter (LVDD), absence resynchronization Baseline EF 27±8% LVDD index 37.1±6.3 mm/m2. occurred 34.5% within 22.6...
Introduction: Myocarditis is usually a benign disease, but sometimes associated with early significant left ventricular (LV) systolic dysfunction. Little known about the predictors for late LV dilatation and dysfunction in these patients. Our study aimed to assess global function progress from admission follow-up patients admitted acute myocarditis describe of at one year follow-up.