A5085133954- Cardiac Imaging and Diagnostics
- Takotsubo Cardiomyopathy and Associated Phenomena
- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Cardiac Valve Diseases and Treatments
- Coronary Interventions and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Issues in Pregnancy
- Sepsis Diagnosis and Treatment
- Pericarditis and Cardiac Tamponade
- Venous Thromboembolism Diagnosis and Management
- Cardiac pacing and defibrillation studies
- Erythropoietin and Anemia Treatment
- Intensive Care Unit Cognitive Disorders
- Aortic Disease and Treatment Approaches
- Cardiac electrophysiology and arrhythmias
- Cardiac Fibrosis and Remodeling
- Cardiovascular and Diving-Related Complications
- Cardiac Health and Mental Health
- Blood Coagulation and Thrombosis Mechanisms
Universitat Autònoma de Barcelona
2016-2025
Corporació Sanitària Parc Taulí
2022-2025
Institute of Research and Innovation Parc Tauli
2025
Hospital de Sant Pau
2014-2022
Centro de Investigación en Red en Enfermedades Cardiovasculares
2018-2022
MedStar Washington Hospital Center
2021-2022
Centro de Investigación Biomédica en Red
2021
Hospital Universitari Joan XXIII de Tarragona
2008
The clinical CardShock risk score, including baseline lactate levels, was recently shown to facilitate stratification in patients with cardiogenic shock (CS). As based on parameters, however, it may not reflect the change mortality response initial therapies. Adrenomedullin is a prognostic biomarker several cardiovascular diseases and associate hemodynamic instability septic shock. aim of our study evaluate value association parameters bioactive adrenomedullin (bio-ADM) CS. prospective,...
The impact of pulmonary artery catheterization (PAC) on survival in patients with cardiogenic shock (CS) is not well established. This study aimed to assess whether Swan-Ganz catheter monitoring related short- and long-term mortality CS.One hundred twenty-nine consecutive a first admission for CS were prospectively enrolled single-center registry between December 2005 May 2009, subsequently followed up over 5.3 years.PAC was used 64% all mean age 68 years (65% men). After adjustment age,...
Abstract Background Mortality from cardiogenic shock remains high and early recognition risk stratification are mandatory for optimal patient allocation to guide treatment strategy. The CardShock the Intra-Aortic Balloon Counterpulsation in Acute Myocardial Infarction Complicated by Cardiogenic Shock (IABP-SHOCK II) scores have shown good results predicting short-term mortality shock. However, date, they not been compared a large cohort of ischaemic non-ischaemic real-world patients. Methods...
MAC is commonly found in patients affected with MR, and it associated high morbidity, mortality worse cardiac surgical outcomes. Transcatheter edge-to-edge repair could be an alternative treatment, although there little evidence this population.The aim of study was to analyse the safety, efficacy durability MitraClip implantation mitral regurgitation (MR) annulus calcification (MAC).We analysed outcomes 61 suitable severe MR moderate or (the "MAC" group) 791 no mild "NoMAC" treated...
Physical activity has benefits on health. However, there is a small risk of effort‐related adverse events. The aim this study to describe exercise‐related severe cardiovascular events and relate them with the type sport performed. We performed ten‐year retrospective in eight Spanish cardiac intensive care units. Adverse were defined as acute myocardial infarction, arrest or syncope related physical activity. From 117 patients included, 109 male (93.2%), mean age was 51.6 ± 12.3 years; 56...
Background: Cardiogenic shock (CS) is the most life-threatening manifestation of acute heart failure. Its complexity and high in-hospital mortality may justify need for invasive monitoring with a pulmonary artery catheter (PAC). Methods: Patients CS included in CardShock Study, an observational, prospective, multicenter, European registry, were analyzed, aiming to describe real-world use PAC, evaluate its impact on 30-day mortality, ability different hemodynamic parameters predict outcomes....
This study aimed to assess the utility of contemporary clinical risk scores and explore ability two biomarkers [growth differentiation factor-15 (GDF-15) soluble ST2 (sST2)] improve prediction in elderly patients with cardiogenic shock. Patients (n = 219) from multicentre CardShock were grouped according age (elderly ≥75 years younger). Characteristics, management, outcome between groups compared. The score IABP-SHOCK II predict in-hospital mortality additional value GDF-15 sST2 was...
Coronary microvascular dysfunction (CMD) has been proposed as a key mechanism in Takotsubo syndrome (TTS). The non-hyperaemic angiography-derived index of microcirculatory resistance (NH-IMRangio) validated pressure-wire-free tool for the assessment coronary microvasculature. We aimed to study presence CMD TTS patients and its association with levels cardiac biomarkers systolic patterns. recruited 181 consecutive admitted who underwent angiography at tertiary center from January 2014 2021....
Although the lungs are potentially highly susceptible to post-cardiac arrest syndrome injury, issue of acute respiratory failure after out-of-hospital cardiac has not been investigated. The objectives this analysis were determine prevalence arrest, its association with inflammatory response and clarify importance for early mortality.The Post-Cardiac Arrest Syndrome (PCAS) pilot study was a prospective, observational, six-centre project (Poland 2, Denmark 1, Spain Italy UK 1), studying...
Using proteomics, we previously found that serum levels of glycosylated (Glyc) forms apolipoprotein J (ApoJ), a cytoprotective and anti-oxidant protein, decrease in the early phase acute myocardial infarction (AMI). We aimed to investigate: (i) ApoJ-Glyc intracellular distribution secretion during ischaemia; (ii) changes circulating AMI; (iii) associations between residual ischaemic risk post-AMI.Glycosylated was investigated in: cells from different organ/tissue origin; pig model de novo...
Cardiogenic shock (CS) is a severe myocardial dysfunction secondary to various cardiac conditions including ST-segment elevation acute infarction (STEMI) and associated with high risk of death. Little known on epigenetic determinants in CS. Here, we investigated plasma miRNAs relation CS stratification STEMI-patients.
Abstract Objectives The aim was to assess the extent of coronary artery disease and revascularization using baseline SYNTAX Score (bSS) residual (rSS) in patients with cardiogenic shock (CS) secondary ST‐segment elevation myocardial infarction (STEMI). prognostic impact (SS) evaluated assessed for additive value over clinical risk scores. Background bSS rSS have been proven be useful stratification stable as well acute syndromes, but they not studied STEMI related CS. Methods Patients from a...
Little information exists about the role of anemia in patients with acute coronary syndromes (ACS) admitted to Intensive Cardiac Care Units (ICCU). The aim this study was assess prevalence and its impact on management outcomes clinical setting.All consecutive eight different ICCUs diagnosis non-ST segment elevation ACS (NSTEACS) were prospectively included. Anemia defined as hemoglobin < 130 g/L men 120 women. association between mortality or readmission at six months assessed by Cox...
Summary The role of erythrocytes in thrombus formation has been often neglected, but some studies have highlighted their active thrombotic events. Free-haemoglobin (Hb) shown to induce oxidative-stress damage. Herein we investigated the coordinated changes heme-related proteins patients with acute-coronary-syndromes (ACS), association ongoing thrombosis and impact on patients’ prognosis. serum proteome STEMI-patients (N=27) within first 6h after event-onset 3d were compared controls (N=60)....