A5009207361- Acute Myocardial Infarction Research
- Cardiac Arrest and Resuscitation
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Cardiac Imaging and Diagnostics
- Atrial Fibrillation Management and Outcomes
- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Cardiac Health and Mental Health
- Cardiac electrophysiology and arrhythmias
- Cardiac, Anesthesia and Surgical Outcomes
- Takotsubo Cardiomyopathy and Associated Phenomena
- GDF15 and Related Biomarkers
- Cardiac Arrhythmias and Treatments
- Fatty Acid Research and Health
- Health and Lifestyle Studies
- Venous Thromboembolism Diagnosis and Management
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Valve Diseases and Treatments
- Cardiac Ischemia and Reperfusion
- Cardiovascular Effects of Exercise
- Nutrition and Health in Aging
- Trauma and Emergency Care Studies
- Neurological Disorders and Treatments
- Cardiovascular and exercise physiology
Hospital Universitari Germans Trias i Pujol
2015-2025
Universitat Autònoma de Barcelona
2017-2020
Centro de Investigación en Red en Enfermedades Cardiovasculares
2017-2020
Instituto de Salud Carlos III
2020
Centro de Investigación Biomédica en Red
2020
Institut d'Investigació en Ciències de la Salut Germans Trias i Pujol
2015
Takotsubo syndrome (TKS) usually mimics an acute coronary syndrome. However, several clinical forms have been reported. Our aim was to assess if different stressful triggers had prognostic influence on TKS, and establish a working classification.We performed analysis including patients with TKS between 2003-2013 from our prospective local database the RETAKO National Registry, fulfilling Mayo criteria. Patients were divided in two groups regarding their potential triggers: (a) none/psychic...
Abstract The IFFANIAM study (Impact of frailty and functional status in elderly patients with ST segment elevation myocardial infarction undergoing primary angioplasty) is an observational multicenter registry to assess the impact on outcomes ‐segment ( STEMI ) angioplasty. age 75 years or older angioplasty will be extensively studied during admission 4 tertiary care Hospitals Spain, assessing their baseline (Barthel index, Lawton‐Brody index), (Fried criteria, FRAIL scale [fatigue,...
Cardiogenic shock (CS) is associated with high short-term mortality and a precise CS risk stratification could guide interventions to improve patient outcome. Here, we developed circulating protein-based score predict among patients CS.Mass spectrometry analysis of 2654 proteins was used for screening in the Barcelona discovery cohort (n = 48). Targeted quantitative proteomics analyses 51 proteins) were independent CardShock 97) derive cross-validate protein classifier. The combination four...
The preferred reperfusion strategy for early ST elevation myocardial infarction (STEMI, defined as time from symptoms onset ≤120 min) in non-capable percutaneous coronary intervention (PCI) centres remains controversial. We sought to compare mortality of situ fibrinolysis vs. PCI transfer a real-life consecutive cohort STEMI.Prospective multicentre STEMI registry (Catalonia 'Codi IAM' network) all-comers centre with symptom first medical contact (FMC) <120 min. Two groups were identified:...
Abstract Background Primary ventricular fibrillation (PVF) is an ominous complication of ST elevation myocardial infarction (STEMI). However, the widespread use reperfusion therapies and post resuscitation care could have reduced prevalence PVF improved prognosis these patients in last years. Purpose The aim to analyze changes over fifteen years, since onset on STEMI Code prevalence, management, times acute phase mortality setting STEMI. Method In 2009, network was officially launched Spain....
Background Coronary artery disease remains a major cause of death despite better outcomes ST‐segment–elevation myocardial infarction (STEMI). We aimed to analyze data from the Ruti‐STEMI registry in‐hospital, 28‐day, and 1‐year events in patients with STEMI over past 3 decades Catalonia, Spain, assess trends prognosis. Methods Results Between February 1989 December 2017, total 7589 were admitted consecutively. Patients grouped into 5 periods: 1994 (period 1), 1995 1999 2), 2000 2004 3), 2005...
Dietary omega-3 eicosapentaenoic acid (EPA) has multiple cardioprotective properties. The proportion of EPA in serum phosphatidylcholine (PC) mirrors dietary intake during previous weeks. Circulating ST-segment elevation myocardial infarction (STEMI) relates to smaller infarct size and preserved long-term ventricular function.The authors investigated whether serum-PC (proxy for marine consumption) levels at the time STEMI were associated with a lower incidence major adverse cardiovascular...
Cardiogenic shock (CS) is an ominous complication of ST-elevation myocardial infarction (STEMI), despite the recent widespread use reperfusion and invasive management. The Ruti-STEMI-Shock registry analysed prevalence 30-day 1-year mortality rates in (STEMI) complicated by CS (STEMI-CS) over last three decades.From February 1989 to December 2018, 493 STEMI-CS patients were consecutively admitted a well-defined geographical area ~850,000 inhabitants. Patients classified into six five-year...
Cardiogenic shock (CS) is a severe complication of acute myocardial infarction (AMI). In AMI-CS, the ST segment deviation on ECG may be elevated (STEMI-CS) or non-elevated (NSTEMI-CS), which influence prognosis. Our aim was to analyze clinical profile, acute-phase prognosis, and long-term outcomes CS relative pattern admission. prospective registry 4647 AMI patients admitted intensive cardiac care unit university hospital between 2010 2019, we compared characteristics, 30-days case fatality,...
The aim of the present study was to evaluate prognostic value Stanniocalcin-2/PAPP-A/IGFBP-4 axis in patients with ST-segment elevation myocardial infarction (STEMI). Observational cohort performed 1085 consecutive STEMI treated early reperfusion between February 2011 and August 2014. Stanniocalcin-2, PAPP-A, IGFBP-4 were measured using state-of-the art immunoassays. primary outcome composite endpoint all-cause mortality readmission due heart failure (HF). Median follow-up 3.3 years (IQR...
In ST-segment-elevation myocardial infarction (STEMI), troponins are not needed for diagnosis: symptoms and ECG data sufficient to activate percutaneous coronary intervention. This study explored the prognostic value of new-generation in a real-life cohort contemporarily treated STEMI.
Abstract Background Growth differentiation factor 15 (GDF-15) in ST-elevation myocardial infarction (STEMI) is prognostic first-generation radioimmunoassays. We examined GDF-15 temporal dynamics STEMI and its predictive value using a first fully automated electrochemiluminescence assay. Methods In this prospective study, circulating concentration was measured at admission (0 h), 12 h 24 1026 consecutive patients treated between February 2011 May 2016 with primary percutaneous coronary...
ABSTRACT Background and objectives Mortality in cardiogenic shock (CS) remains elevated, with the potential for CS causes to impact prognosis risk stratification. The aim was investigate in-hospital mortality patients according aetiology. We also assessed prognostic accuracy of CardShock IABP-SHOCK II scores. Methods Shock-CAT study a multicentre, prospective, observational conducted from December 2018-November 2019 eight University hospitals Catalonia, including non-selected consecutive...
Mortality in cardiogenic shock (CS) remains elevated, with the potential for CS causes to impact prognosis and risk stratification. The aim was investigate in-hospital mortality patients according aetiology. We also assessed prognostic accuracy of CardShock IABP-SHOCK II scores.
Growth differentiation factor 15 (GDF-15) is an inflammatory cytokine released in response to tissue injury. It has prognostic value cardiovascular diseases and other acute chronic conditions. Here, we explored the of GDF-15 as early predictor neurologic outcome after out-of-hospital cardiac arrest (OHCA).Prospective registry study patients coma OHCA, admitted intensive care unit from a single university center. Serum levels were measured on admission. Neurologic status was evaluated...
Abstract Background Coronary care units were established in the 1960s to reduce acute-phase mortality acute coronary syndrome. In 21st century, original unit concept has evolved into an intensive cardiovascular unit. The aim of this study was analyse trend changes characteristics and patients admitted a over past three decades. Method Between February 1989 December 2017, total 18,334 consecutively university hospital Barcelona. Data analysed five time frames: 1989–1994, 1995–1999, 2000–2004,...