A5068464886- Heart Failure Treatment and Management
- Cardiovascular Function and Risk Factors
- Diabetes Treatment and Management
- Nutrition and Health in Aging
- Potassium and Related Disorders
- Cardiac pacing and defibrillation studies
- Electrolyte and hormonal disorders
- Venous Thromboembolism Diagnosis and Management
- Inflammatory Biomarkers in Disease Prognosis
- Lipoproteins and Cardiovascular Health
- Acute Myocardial Infarction Research
- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Medication Adherence and Compliance
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Imaging and Diagnostics
- Body Composition Measurement Techniques
- GDF15 and Related Biomarkers
- Cardiac Valve Diseases and Treatments
- Cardiac electrophysiology and arrhythmias
- Heart Rate Variability and Autonomic Control
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Sepsis Diagnosis and Treatment
- Respiratory Support and Mechanisms
- Cardiovascular and exercise physiology
Hospital de São João
2016-2025
Universidade do Porto
2015-2025
Centro de Genética Clínica
2021-2024
Empresa de Desenvolvimento Mineiro (Portugal)
2024
Centro Universitário de João Pessoa
2022
Faculdade de Medicina do ABC
2017-2018
GTx (United States)
2018
Sociedad Española de Medicina Interna
2018
Departamento de Epidemiología
2014
i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto
2013
The early identification of acute heart failure (HF) patients with type 1 cardio-renal syndrome should be the first step for developing prevention and treatment strategies these patients. This study aimed to assess performance neutrophil gelatinase-associated lipocalin (NGAL) cystatin C in detection HF.One-hundred nineteen admitted HF were studied. NGAL creatinine measured hospitalization morning; was also at least after 48 72 hours. Physicians blinded levels. Type defined as an increase...
Prealbumin is one of the best indicators nutritional status. We previously showed that prealbumin predicted in-hospital mortality in heart failure (HF) patients. evaluated if a low discharge after admission with acute HF would predict morbidity and mortality.We conducted prospective observational study. Patients admitted primary diagnosis were studied. Follow-up was up to 6 months. Endpoints analysed were: all-cause HF-death; worsening hospitalisation. ≤15.0 mg/dL those >15 compared. A...
Abstract Background: Increased levels of platelet distribution width (PDW) can predict cardiac death and infarction recurrence in acute myocardial infarction. PDW appears to be a prognosis marker heart failure (HF); however, its impact on chronic HF is still unknown. We investigated the HF. Methods: retrospectively analyzed outpatients with left ventricular systolic dysfunction (LVSD) from January 2012 May 2018. Patients no data or preserved recovered ejection fraction were excluded. The...
Abstract Background: The impact of systolic blood pressure (SBP) variation on chronic heart failure (HF) is largely unknown. We assessed the SBP in patients with HF. Methods: This a retrospective analysis adult ambulatory HF left ventricular dysfunction (LVSD). = at index visit – 1-year visit. Patients dying first year or missing data concerning were excluded. increase ≥10 mmHg during compared remaining. Determinants by binary logistic regression analysis. followed up from to 5 years....
In heart failure (HF), lower total cholesterol (TC) levels associate with poor outcomes. Whether TC variations portend prognostic implication is unknown. We aimed to evaluate the impact of variation in HF. retrospectively analyzed adult outpatients chronic HF systolic dysfunction evaluated between January/2012 and December/2020. Patients no measurement at baseline or 1-year follow-up visit were excluded. Variation during first year = [(baseline - visit)/baseline TC] × 100. followed-up until...
Adherence to medication is crucial improve clinical outcomes in patients with heart failure (HF). However, at least 1 out of 4 nonadherent his or her medication. Several studies have quantified adherence HF patients, monitoring only drug the Medication Event Monitoring System (MEMS). Some authors argued that reflects whole behavior, although there some evidence important differences distinct classes. Furthermore, characteristics could be a relevant predictor adherence, and different drugs...
Abstract Aims Growth differentiation factor (GDF)‐15 mirrors inflammation and oxidative stress in cardiovascular diseases. Brain natriuretic peptide (BNP) is associated with cardiomyocyte stretch heart failure (HF). The objective of this study was to evaluate the prognostic impact plasma GDF‐15 BNP acute HF. Methods results We studied a subgroup patients prospectively recruited an HF registry (follow‐up: 2 years; endpoint: all‐cause mortality). Cox regression multivariate models were built...
Since the Randomized Aldactone Evaluation Study (RALES), use of spironolactone is recommended in systolic heart failure (HF) patients that have been New York Heart Association (NYHA) class III or IV. There limited information on use, side effects, and withdrawal rate routine clinical practice.Side effects related to are more common than reported trials.Patients who had moderate severe left ventricular dysfunction (LVSD) under optimized medical therapy were included. We introduced those with...
The prognostic role of C-reactive protein (CRP) in acute heart failure (HF) is not fully understood, and the impact an infectious process its risk-stratification power was previously evaluated.As CRP inflammatory marker, value HF probably different patients with without concurrent infection.We recruited admitted to our hospital due from October 2006 2007. All were given treatment at discretion attending physician. Serum measured discharge 225 patients. We followed for 3 months after assess...
Background. Congenital subaortic stenosis (SAS) has a high recurrence rate after surgical correction. Aortic valve disease frequently coexists with SAS, being its occurrence and progression unpredictable. We aimed to assess predictors of SAS aortic progression. Methods. Retrospective analysis 51 patients followed in congenital heart clinic tertiary care hospital from July 1982 October 2009. Results. The mean age at diagnosis was 15 years 28 (54.9%) were men. regurgitation present 23 (45.1%)...